26S proteasome non ATPase regulatory subunit 12 (PSMD12) (NM_174871) Human 3' UTR Clone

Specifications

Product Data
Product Name	26S proteasome non ATPase regulatory subunit 12 (PSMD12) (NM_174871) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	p55; Rpn5; STISS
ACCN	NM_174871
Insert Size	364 bp
Sequence Data	Insert Sequence (showhide) >SC204540 3' UTR clone of NM_174871 The sequence shown below is from the reference sequence of NM_174871. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CGCATCTCATAGCCAAAGAGGAGATGATACATAATCTACAATAAGGGTCTTAGTGCTTTAGAAAAAAGTT AAAATTGGAAGTCATTAAAAAAAGACTGTTATAATGGTGTATATGTTGGGGTTTTTTTTCTAAGCTTCTT TGTCTTAAATTTTAAAATAGTGAATATGTTTGAGACTCCCTTTGACCTTTCAGTTCCCCAAGTTCATTGT TAACTTTGCATTTGCAATTGGTGCAAAAATACAGATTTCTGTCGTCTGAATACACAAAAAGTTGTGTCAT AACTTACCCAGATATGTTTTTCTATCATTTGAAACCTTTTTAGCTACTGTTTGTTTTCATTCAACTAACA AACATATTCCAATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_174871.2
Synonyms	p55; Rpn5; STISS
Summary	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Locus ID	5718

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