EPM2A (NM_001018041) Human 3' UTR Clone

Specifications

Product Data
Product Name	EPM2A (NM_001018041) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	EPM2; MELF
ACCN	NM_001018041
Insert Size	420 bp
Sequence Data	Insert Sequence (showhide) >SC205379 3’UTR clone of NM_001018041 The sequence shown below is from the reference sequence of NM_001018041. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCAGCTAGCCAGGACACATTTCCACTATAATTTTACAAAGTTAAATTTATAAGCTAGCATTAAGTAAAG TGAAGTCCAGCTCCCTTGCTAAAAATAACTAGAGGTAATAATTGGTATTCAGGTAACTCATTTACAGTC ATAATGTGTTGTGAAAATTTAATCTTAAAAATTAAATTTTTAAACTATGTGGGTCTGTGAATTTCTTTA ATGTCTAAGAAATCCAGCTTCATAATTTCCATGATACAAAGATCTTTTTTCAGGTGGATTTTTACCTTT GTTCCTTTTGCTCTGATAGACAAAATCAGTTTAGGACTATTAAAGAATGTTTTGGAATAAACTGTCTTT TTCCTCAATGAATGGGATGTCTAATGTATTTCAAAATCACCCAAAACTTTTGGCAAATAAAAGCATTTA AAAAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001018041.2
Synonyms	EPM2; MELF
Summary	This gene encodes a dual-specificity phosphatase and may be involved in the regulation of glycogen metabolism. The protein acts on complex carbohydrates to prevent glycogen hyperphosphorylation, thus avoiding the formation of insoluble aggregates. Loss-of-function mutations in this gene have been associated with Lafora disease, a rare, adult-onset recessive neurodegenerative disease, which results in myoclonus epilepsy and usually results in death several years after the onset of symptoms. The disease is characterized by the accumulation of insoluble particles called Lafora bodies, which are derived from glycogen. [provided by RefSeq, Jan 2018]
Locus ID	7957
MW	16.2

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