PCBP1 (NM_006196) Human 3' UTR Clone

Specifications

Product Data
Product Name	PCBP1 (NM_006196) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HEL-S-85; hnRNP-E1; hnRNP-X; HNRPE1; HNRPX
ACCN	NM_006196
Insert Size	419 bp
Sequence Data	Insert Sequence (showhide) >SC205517 3’UTR clone of NM_006196 The sequence shown below is from the reference sequence of NM_006196. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCCTCTGAGAAGGGCATGGGGTGCAGCTAGAACAGTGTAGGTTCCCTCAATAACCCCTTTCTGCTGTTC TCCCATGATCCAACTGTGTAATTTCTGGTCAGTGATTCCAGGTTTTAAATAATTTGTAAGTGTTCAGTT TCTACACAACTTTATCATCCGCTAAGAATTTAAAAATCACATTCTCTGTTCAGCTGTTAATGCTGGGAT CCATATTTAGTTTTATAAGCTTTTCCCTGTTTTTAGTTTTGTTTTGGGTTTTTTGGCTCATGAATTTTA TTTCTGTTTGTCGATAAGAAATGTAAGAGTGGAATGTTAATAAATTTCAGTTTAGTTCTGTAATGTCAA GAATTTAAGAATTAAAAAACGGATTGGTTAAAAAATGCTTCATATTTGAAAAAGCTGGGAATTGCTGTC TTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006196.4
Synonyms	HEL-S-85; hnRNP-E1; hnRNP-X; HNRPE1; HNRPX
Summary	This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq, Jul 2008]
Locus ID	5093
MW	15.8

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