KCNQ2 (NM_172107) Human 3' UTR Clone

Specifications

Product Data
Product Name	KCNQ2 (NM_172107) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BFNC; DEE7; EBN; EBN1; ENB1; HNSPC; KCNA11; KV7.2
ACCN	NM_172107
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC206138 3’UTR clone of NM_172107 The sequence shown below is from the reference sequence of NM_172107. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACGTGGGCTGGGCCGGGCCCAGGAAGTGAGGCGGCGCTGGGCCAGTGGACCCGCCCGCGGCCCTCCTC AGCACGGTGCCTCCGAGGTTTTGAGGCGGGAACCCTCTGGGGCCCTTTTCTTACAGTAACTGAGTGTGG CGGGAAGGGTGGGCCCTGGAGGGGCCCATGTGGGCTGAAGGATGGGGGCTCCTGGCAGTGACCTTTTAC AAAAGTTATTTTCCAACAGGGGCTGGAGGGCTGGGCAGGGCCCTGTGGCTCCAGGAGCAGCGTGCAGGA GCAAGGCTGCCCTGTCCACTCTGCTCAGGGCCGCGGCCGACATCAGCCCGGTGTGAGGAGGGGCGGGAG TGATGACGGGGTGTTGCCAGCGTGGCAACAGGCGGGGGGTTGTCTCAGCCGAGCCCAGGGGAGGCACAA AGGGCAGGCCTGTTCCCTGAGGACCTGCGCAAAGGGCGGGCCTGTTTGGTGAGGACCTGCGGCCTTGGG TCCCGGTGGGGTTTCCGGGCAGCTACAGGCGGGTGTGGCCGGCCGCTGTGCGTGGCCTCTGCCTTCACA CCTGACCTGCCCGGCGGGCTTTCCTGTTCCCCACCTCAGGGGCGCCCAAATACAGAGCTATTGGTTGGC GTCTTCTCCCTGTACCTTCTGGGATCTGAGGGCTCTTTCCATGGAAGCCAGCCCCGAGGTGGAGACCTT CGCCTGCAGCCGAGGAGCGGGTGGGGCCTGGGAACCAAACTGGAGCCAGAGTGGACGTCCAGCCCTCTG GTCTTGGCCTCCAGAGGGAGGGCCTGGCTCACGGTGGGGCCAGGGAGCCGGCTCCAAAGGGTCTTCAAA AAGGGGGTCCTTGGGGGCTCCAGCTGCCTCGCCCTGGCCTTTCTGTGGGTGCGTGAGAGCCAGCAGCAC CCCAGCCTTGGAGACCGGGGGGGCAGGACCCCAAGTCCTCCCCTCTCTCCTGACTGCCCTGGCCGGGTG CCGGCACTGCGAGACCCACCTGGTGAGCAGGCCTCACAGTTCTTAGCCAGGGCCCCACCTCGCCTGTGT CCCACCAGTGCCCCGACAGACCTGGGGCAGGGCTGGGCCATGATGCAGCGGGCCAGGATAGCCTCCACC GTCAGCACAGGGCCGCCCTCCCCGCCTTTCCGGAGGAAACCACTCCCACCTCAGCCCAGCTGTGCGCCC TCCCTAGCTCTCCTGCCCCCTGGAGCTGATGGCCCCTTCTCCACTGACCGATTCCTTAGCGGGGCCTCT TGGGGTCTCGGGCCTCGGGTGCACCGTCCCATGCCCGTCCTGTTGTGGGCACCGTGGCCCTTGGGGCAG GCGGCTCTAATGCGGGAGCGAGTCCCTAGCTCCAGACTTAAGAACCAGACCCCGGGAGCATCTGGCATT TGGCGTGACGGCGTCGCAGGCGGGCCTGGGCTCCCTGGAGAGTGGCCTCCCTGGGAGTGAGCAGGGCTG GGGTCGTGGGCGCAAATACTCCTGCAGAGCAAGTGCAGGGGAGTCCTGGGCCCGTTTCTCCTCCACCTG CGTTTTCAGTGCACTTGGCTTGGCTGGGAGGTCCTGAGGCCCTGAGGCCAGCAGGGGAACCAGTCCTGA GGGAGAGGACTTTGAAAGCAGCATTTGAGGGTCGTACGCCCCTGGCTGGTGGGGGTCCTGGCGCTCAGG GTGTTCGGGGAGCCATGTCTGGCGTCCATTGTGGGGAGCTGCTGCCCTGGCCTCTCTGCCTACCCCCAG CCCGGCCAGGGCACTCCCAGGCCCTGTCGCCATTGAGGTGCCTCCGCTGGGCTGTCTCCTCACCCCTCC CTGTGCTGGAGCCTGTCCCAAAAAGGTGCCAACTGGGAGGCCTCGGAAGCCACTGTCCAGGCTCCCACT GCCTGTCTGCTCTGTTCCCAAAGGCAGCGTGTGTGGCCTCGGGCCCTGCGGTGGCATGAAGCATCCCTT CTGGTGTGGGCATCGCTACGTGTTTTGGGGGCAGCGTTTCACGGCGGTGCCCTTGCTGTCTCCCTTGG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_172107.4
Synonyms	BFNC; DEE7; EBN; EBN1; ENB1; HNSPC; KCNA11; KV7.2
Summary	The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Locus ID	3785
MW	70.6

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