TAP2 (NM_018833) Human 3' UTR Clone

Specifications

Product Data
Product Name	TAP2 (NM_018833) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ABC18; ABCB3; APT2; D6S217E; PSF-2; PSF2; RING11
ACCN	NM_018833
Insert Size	488 bp
Sequence Data	Insert Sequence (showhide) >SC206148 3’UTR clone of NM_018833 The sequence shown below is from the reference sequence of NM_018833. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAAACCCTTTGGAAGTTCATGATATTTTGAATTTCAATGGATATTTCCTGGGAATAATGAGTTCAAATG AACGAATATGTGGAACAAAGCATCACCAACATTTATTTTTTCAGGATGAGGTGATGGACAAAACCATCA CAGGGAAATTGAGGCAAATAGTACATGTAAAACAATACTTCGGGTGAGTCCACCTATCCCAAAGTCGTA TCAAAGAAGTGGCTGCAGATTGGAGCCCAAAGCCTTTGGTTCCTCAGTTTCCAAATGGATTCTCACTAG GTGGGATCATGAGTTTGCTTTGGACACCCCAAATTCTAACTATTTCTTTTGTTTCTTACATCCTTTCCC TCTTCCCCAGCCCCTTCCCCTCATGTTACACCTCTTGCTGGTTTGAGACGTCAATCACCACTGAGAAAG AATTAAACCAGTATTTTGAGCTGGCAAAATTCTTAGCCTAGTACAATTCCTTCAATTAAACTGTAGCTC AACAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_018833.3
Synonyms	ABC18; ABCB3; APT2; D6S217E; PSF-2; PSF2; RING11
Summary	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]
Locus ID	6891
MW	18.7

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