PANK2 (NM_153638) Human 3' UTR Clone

Specifications

Product Data
Product Name	PANK2 (NM_153638) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	C20orf48; HARP; HSS; NBIA1; PKAN
ACCN	NM_153638
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC207515 3’UTR clone of NM_153638 The sequence shown below is from the reference sequence of NM_153638. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCACTCCTTGAGCTGTTGAAGATCCCGTGATCATTACCTGGGGAGGGGTTCCTGAAACCTTCCACAATG GGATCTGTGGACTTTCATTTTTTTAAGAGACTTACTCAATTTCATGACTGTACTACCTGAAACAAAGTG AGAAAGGACAGGTGTATTTTTCTAAGTCATCAAGATAAATCCTTAAGAATTCAGTCTAAATTAGCAACC AGGAAGGAAAAATATATTAAAAACAACAAAAAAGTGGCACATGTCCAGGCAGTGTGAGGATTTGCTGTA TATAAGTTGCCTGCTTTGTATTTTTGAAATCTCTGCATCACTCATTGGAAGTGCTTCTGAAGAGAGCTG CTCTGTGTTCAGTTGACTGGTTTTGTGTCCTGTTTGAACTTGCTGAATGTAAGGCAGGCTACTATGCGT TATAATCTAATCACAATTTGTCAATATGGTCTTGGCAATCATCTGTGCATTACTCTGGTTTGCATTAAG CCTGTGTGTGAACTTACTGTAAAACATGTTTTATTTCAAGGTTCTGCAAAATTAATTGGGCAGGTTAAT TGTGTACCTGAAACTTAACAAGCAGTTTTTGGAAGGGCAGTTCCACGTTACTTTACACTAAATCCTGGG AATGAATGTCTGGAGAGACAGGGCTTCTTTTCTTGGCAGAATTTCCTTGGGTAGTGGGCGGACTGTTCT GATGCAAGTGGGTACACTGGCAGAAGCAGCACAATCTGGAGGACTAACATGAGTCAGCAGGGCCACTAG AATTGACACCCCCTCAGGGGATCAGGGAGAATCTGGTTTTTCTTTCAGGCTAAGTAGAAAAGGAAGAAC TGAAGTGTCTGTCAAAGAACTCATGGGGAGTGGGGGGTCCTTCAGGGCACTGTGGCACTTGGGAGGTGA GTCTCAGAAGACTGCCTGAGGAGAGTGCCAGGCTGCAGGTGCTCTTGGTAGGGGCTGAAGCTTTTCTTT CTGCTTTGCAGAATAATTTCAAAAGCCTTTCCCAAGGAGAGAATGCACCTTTTATATCTGAGGTCTTAA GTGGTGCCCATATTGCTGTTGAAGGCAAGGATGGGCCTGTACAAAGCAGCCTTGGACCAGGAGGGAAAA CCCCAAGGCTCTGCAGCCTCCCTGCTCCCCTCCGTTTAAGGCTGTGGTCAGGGAGGGATGGGCAGGGTG CCAGCCGCATGGAGGCAGCAGAGACACCCGTGTTCCAGCTGGGGCAAGGGGAACTGATATGTGGGCTGT GGGCTGTTCCACTAGGCGTGGCCACCTCTGCACATGGGCCTTGGCACTTAGGAAATATGGGTGCTGCTG CATTGGGACCTTGTGTGGGTGCAGAGCAGGATGGCTGCTGCGTGGAGGGTAATTTTGTCCCCTGGAGAG TGATTGGTGACCCTCTTCCCTGCTGCTGCTGTTTGCAGGCTCCTGGCCTATACTACCTCTGACGCCCTG ATCCTGAGTTCCTCTGCCCTCCTCTGCTGCCAGCAGCGCTGTTGGTGGCCTCACCCTCCTCCAGTACCC AGGCACCAAAGATGGCACCACCATCCTCCTGCTTGTACCACAGGGTGCTGCTCCCTGGGCCAACTCCTG TGAACTTGCTCACTTCCCATGGAGACCGAGGCCAGGGCCTGCCCCTCTGAGGCCCCTGTTTTGTGGTCC TGCTGCCTCTGCTGTGCTGCGTTCAGGAGGTTGTCCACTGCTCGACGTGGGTCACCATGCAGCCCTTGC TGTTCCCACAATTTAACAGAAAAGGAAACTGAACGGATGAGTAAGGCTGCCCAGGGTCACTCAGCTGGA AAAGAGTAGAGCTGGACTCAAACCCGGGACTGTCTGTCTCTGGTGCCTGAGTTGGGAAGACGCTGTTGA TGTCCCCTTCTGCCTCGCTTTGAGCTTCCTCCTCCGTGGGCCCTCCCCCTACTCTAGAGAAACTAGTCC ATTCCCTCATGTTCCACCTTGTGCTCAGTAAACCCTGTCACTCCACAGCAGGGTTTTTGAGACAGTCT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_153638.4
Synonyms	C20orf48; HARP; HSS; NBIA1; PKAN
Summary	This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
Locus ID	80025
MW	74.8

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