Nicastrin (NCSTN) (NM_015331) Human 3' UTR Clone
CAT#: SC208960
3' UTR clone of nicastrin (NCSTN) for miRNA target validation
Need custom modification / cloning service?
Get a free quote
CNY 4,845.00
货期*
3周
规格
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (2)
Specifications
Product Data | |
Product Name | Nicastrin (NCSTN) (NM_015331) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | ATAG1874 |
ACCN | NM_015331 |
Insert Size | 708 bp |
Sequence Data |
>SC208960 3’UTR clone of NM_015331
The sequence shown below is from the reference sequence of NM_015331. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCCGGGAGCCAGGAGCTGTGTCATACTGAGGAGGACCCCAGCTTTTCTTGCCAGCTCAGCAGTTCACT TCCTAGAGCATCTGTCCCACTGGGACACAACCACTAATTTGTCACTGGAACCTCCCTGGGCCTGTCTCA GATTGGGATTAACATAAAAGAGTGGAACTATCCAAAAGAGACAGGGAGAAATAAATAAATTGCCTCCCT TCCTCCGCTCCCCTTTCCCATCACCCCTTCCCCATTTCCTCTTCCTTCTCTACTCATGCCAGATTTTGG GATTACAAATAGAAGCTTCTTGCTCCTGTTTAACTCCCTAGTTACCCACCCTAATTTGCCCTTCAGGAC CCTTCTACTTTTTCCTTCCTGCCCTGTACCTCTCTCTGCTCCTCACCCCCACCCCTGTACCCAGCCACC TTCCTGACTGGGAAGGACATAAAAGGTTTAATGTCAGGGTCAAACTACATTGAGCCCCTGAGGACAGGG GCATCTCTGGGCTGAGCCTACTGTCTCCTTCCCACTGTCCTTTCTCCAGGCCCTCAGATGGCACATTAG GGTGGGCGTGCTGCGGGTGGGTATCCCACCTCCAGCCCACAGTGCTCAGTTGTACTTTTTATTAAGCTG TAATATCTATTTTTGTTTTTGTCTTTTTCCTTTATTCTTTTTGTAAATATATATATAATGAGTTTCATT AAAATAGATTATCCCACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_015331.3 |
Synonyms | ATAG1874 |
Summary | This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Mutations in this gene are associated with familial acne inversa. A pseudogene of this gene is present on chromosome 21. Alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Feb 2014] |
Locus ID | 23385 |
MW | 26 |
Documents
Product Manuals |
FAQs |
Resources
Customer
Reviews
Loading...