ASK1 (MAP3K5) (NM_005923) Human 3' UTR Clone

CAT#: SC209333

3' UTR clone of mitogen-activated protein kinase kinase kinase 5 (MAP3K5) for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name ASK1 (MAP3K5) (NM_005923) Human 3' UTR Clone
Vector pMirTarget
Synonyms ASK1; MAPKKK5; MEKK5
ACCN NM_005923
Insert Size 742 bp
Sequence Data
>SC209333 3’UTR clone of NM_005923
The sequence shown below is from the reference sequence of NM_005923. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
ATCATTGACTTTCGAAACAAACAGACTTGACTGTTGCTCAATCTAATCTTCGATGGAAATTCTAAAAAT
TAATACAGAGCTGATCTTCTTGGGGGTGGGAAAATCGAAGGGAGAGGAGAAAGGCGCTGCACTTTAAAT
CCAGTATTTGTTTACTCATGTTAAAAAAAAAAAAAACAGACAAAACACACTGAAATTTCCTAACTACAT
CTATTTCTATAATTTTTAAGGACTCTTCATAAGGACTCTTAAAATAATCCTGAACATTAGAACCCTAAT
GTTCAGGAAGATTTTAATCTAAGCATTTTTATGGAAATATTTTTAATGCAGCAGCTATTGCACTTCAGC
CAAATGTTTATTTCACACAAAACGGATGTAACATTTCATGTGATCGTGCACCACTGGAACAAAACCAAA
ATGTGACCATAACTGTTTAGGCTTCTGTGTGTTTGTAATATGCTCTAATAATCTGAGTAGAAATGCGTA
ATTTCAATTACTGTATAAAGTTTATGTTTTTTTAAGTGTGCAGAATCTGAGAGCAATGGTTTTTACTTC
TCTGTGTTAATTGTAATATTGACTCTATTTTGTAACTTAAGTTTCTGACCTGTCGTACATTTGTTTGAG
TCGTTTATGTACTACTGAACTGTACCAGTTGCACATGCTTGAACTGTAGTAATGTTAGCTTGTTCTAAA
GCTATCCATTGTGTCATATTTACTCTAAAAATTAAAGAGACTCTCAACATAC
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_005923.4
Synonyms ASK1; MAPKKK5; MEKK5
Summary Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008]
Locus ID 4217
MW 28.7
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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