KCTD6 (NM_001128214) Human 3' UTR Clone

CAT#: SC209376

3' UTR clone of potassium channel tetramerisation domain containing 6 (KCTD6) transcript variant 2 for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name KCTD6 (NM_001128214) Human 3' UTR Clone
Vector pMirTarget
Synonyms KCASH3
ACCN NM_001128214
Insert Size 754 bp
Sequence Data
>SC209376 3’UTR clone of NM_001128214
The sequence shown below is from the reference sequence of NM_001128214. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
TGTAGGCTAGCCCGGAAGACAGACGACTGATCTCCGACCCTGCCACAGGTTCCTGGAAAGACTCTCCAG
GAAATGGAAGATACTGATTTTTTTTTTTAAATCACAGTGTGAGATATTTTTTTTCTTTTAAATAGTTGT
ATTTATTTGAAGGCAGTGAGGACCAGAAGGAAGTTTTGTGCTTTGGCAGACTCCTCCATGTTTTGTTCC
CTTCCCCCTGAGTATGCATGTGCCTGTTCAGAGTCTCCAGATACCTTTTTTATAAAAAGAAGTCTGAAA
ATCATTATGGTATATAATCTACCCTTAACAGAGCTTTTCTTATTACAGTGCTAAAATGATTTCTGATAA
AATGGTCCCTAACTCAACTAGAAGGCTAAAAATACAAGAATGAAAGAATAAGCAGAGTACTCATGATGC
CTTTGAGAAAAATCAAAACATCATGTAGGGTGACCTAGTTTCCAAACCAATAAATAAGTAGTATTGTAA
TATTAAAGGAAAACTGTTCCAATCATTTAAAAGTACTTATTAAGTACTGCTTTTTACAGTTATGACAAC
TGTTTCTTTCTATGCATATAAATCAAGGAACCAAATATCTGTAGCCATGGAAATGTCTGACTAGAAATA
TTTATATTGAATTCTGAATACAAAATGTCCCTGTGGTAGAAAACTTACTCTTTATGCCTGGTGCAGTAT
AATTCCCAAGTGTACTGTCTACCAGAAAAAAAAAACAAAACTAATAAAAAATGAAATATGAAAA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_001128214.2
Synonyms KCASH3
Summary Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887).[UniProtKB/Swiss-Prot Function]
Locus ID 200845
MW 29.2
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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