CDC42 (NM_044472) Human 3' UTR Clone

Specifications

Product Data
Product Name	CDC42 (NM_044472) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CDC42Hs; G25K; TKS
ACCN	NM_044472
Insert Size	805 bp
Sequence Data	Insert Sequence (showhide) >SC209889 3’UTR clone of NM_044472 The sequence shown below is from the reference sequence of NM_044472. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAACCCAAAAGGAAGTGCTGTATATTCTAAACTGTTTTCTCCTTCCCTTCTTTGCTGCTGCTTCCTGTC CCACTACTGTAGAAAGATCGTTTAAAAACAAAGGAATAAAACCATCCTGTTTGAAAGCCTCTGCGTCTT TTTACTCACCACCTTAGAGCAACCTCTGTATTAGTTTTTGATCAAGAATGCAATATCATATAAATTTTT TGTGATCAGTAGTCAAGTTGGACTTGTTTTAACGTTCTGCTGCTTGAGTTGCCTGATGCTCAGAGCTTT TTGGTTTGGATTACTATTGCAAAAGGGAACTTGGTCTGGCTTTAAGAATGTCCTCTTGGAGAAAATAAC AAGAGTTTTAACACTTCTAGATCTTAGTTCTAGATGGAGAAAGTAACACAAACATCATTTTACTCTTAT GATCAATTGTTAATTGTAATTGCATGACAAACCTTATGGAAAAGGGGTGACCTAGTAGAGTGTAATGGG GAAGGGAGGATTCTTTTCTGGTTTTCCTTTGTGCGGTGAAACTTTGTGTTGCTGTTGCTTTGGCTGTCT GTGCTGTAGTGGAGTATTTGTCAGTCTGGGGTGGGGAAGATATTGATGTATCTGCTACTGCTTTATGAG TTCATTTGTTACATTATCTTTTAAGAATAACATCCATTTAAACAGTTGACTTACAGTTTGTTAATGCTG AGATGTAAAGCTGCCACCTTTATATTTTCCTGCTTCTGATTTTATTGTGAGGGAAATATACAATTGTGG TTACCTTCAAATTTTGAAATTAAAAATATACAACCGTTTGTATAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_044472.3
Synonyms	CDC42Hs; G25K; TKS
Summary	The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Locus ID	998
MW	31.4

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