EXOSC6 (NM_058219) Human 3' UTR Clone

Specifications

Product Data
Product Name	EXOSC6 (NM_058219) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	EAP4; hMtr3p; MTR3; Mtr3p; p11
ACCN	NM_058219
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC210743 3’UTR clone of NM_058219 The sequence shown below is from the reference sequence of NM_058219. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGCCGCAGGGGCGCCGCCGCCCAGCCCTGAACCAGAAGCCTGAGCAACTACGGACGCAAGCCGAGGACC GTGCTGCCGCCGTCCACGAAAAGACCCGCGCCATCGGCCTCCAGTTTGCGTCGAGAATTCCTGGAAGGG CCCTGATATGACTGTGGTTGGACTGACCTGACTGCCAGATGGTGGGACTTGGTCTGGAGCAGGGACTAC TTGGAATGATAAAGGCAAAACTCAACAGCCCCTGGAGCTGCGCTTGTGGTGGAGCTGGACCCTGAAATT ACCTGGACCTTTTTTTTAGAGACAGGGTTTCTTTCTGCAGTCTCAAACTCCTAGCCTTGATTGATCCTC CTGCCTTGGCCTCCCAAAGTGCTGGGACTACAGGTGCATGCAACCACACCTGGCTAATTTTCTTTTCTT CTTTCTTTCTTTTTTTTTTTTTTTTTTTTTTGATGGAGTCTTGTTCTGTTGCCCAGGCTGGAGTGCAAT GGTGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAATCCATTCTCCTGCCTCAGCCTCCCAA GTAGCTGGGATTACAGGCACATGCCTCCATACCGGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTT CGCCATGTGGGCCAGGCTGTTCTCGAATGCCTGACCTCAGGTGATCCACCCGCCTTGGCCTCCCAAAGT GCTGGAATTACAGGTGTGAGCCACTGTGCCCAGCTGAGTAAATTTCTTGATTGCACAGAATGTACGGTG ATATTGGCGGACTTAAGGACATCGAATTGTTTATCAGGAATAAAGTATTATGTGTGTTTTCTGCGGCCC TGGATAATGCTGTAGCATTCAGGGTCGATTGAGTAAAAAAAATGTAGAGATGGTTTCCTGTTTGTTTTT GCTTCTAGTTTTCATTCATTTGCTATTTATTCTCTTCTGGCTTTGCTTGTGTATGCATATATATAAAAC CATTATTATTATTATTATTATTTTTAGTTTCTAGTGGAAGGCTTTTATTTGGTTCTGTGAATAGTCATT TTGTTTCCTAAGAACTTCCAGCAAGTTGTATTCATTCCATTCATCTAGAATTCCTAGGCTGCCTTTGTC GGGCCTGCAGGTATTAATGGAGAATAGCAGCTTTTTATTTTTTTATATTTATTTTTTGAGACAGAGTCT CACTCTGTTGCCCAGGCTGGAGTGCAATGGCGCGATCTCAGCTCACTGCAACCTCCGCCTCAGAGGTTC AAGTGATTCTCCTGCCTCAGCCTCTGGAATAGCTGGGACTACAGGCACCTGCCACCACACCCAGCTAAC TTTTTGTATTTTTAGAGAAGATGGGGTTTCATCATGTTGGCCAAGCTGGTCTCAAACTCCTGATCTCAG TGATCCATCTGCCTCAGCCTCCCAAAGTTATAAGATTTTTTTCCTCTGGTTTTTAGTAAATGTTTTTTT TGAGATTGCTTAGCACCAGAATGATTTGCAAATTTGAAAATAGGAACTCCACTAGGAATGCCGGATAGA AGAGTGCTTCACATTTGTAGAGGGAGACAAGAACTAAATATCACGACGTCTTTCTGAGCCTTTTGGTTT GCTAACGTGCCCCAAATTCTTATTCCAAACGGTATAAGATAATTATGTGTAAATGAATACCAGCTCTAC TTAGTTTTATTTCATATTTGTGTATCTGAATATATTAAAATATCTTTTTTTTTTTTTTGATGCGGAGTC TTGCTCTGTTGTCCAGCCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTT CAAGCGATTCTCCTGCCTCAGCCTCCTAAGTAGCTGGTATTACAGGAGTGTGCCATTAGCCTGGCTAAT TTTTGTATTTTTAGTAGAGATGGATTTTCATTGTGTTGGCCATGCTGGTCTTGAACTCCTGACCTCAAG TGATCCTCCTGCCTTGGCCTCCCAAAGTACTGTGATTACTATCATGAGCCACCACACCTGGCCTAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_058219.3
Synonyms	EAP4; hMtr3p; MTR3; Mtr3p; p11
Summary	This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. [provided by RefSeq, Jul 2008]
Locus ID	118460
MW	75.3

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