FADD (NM_003824) Human 3' UTR Clone
CAT#: SC211184
3' UTR clone of Fas (TNFRSF6)-associated via death domain (FADD) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | FADD (NM_003824) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | GIG3; MORT1 |
ACCN | NM_003824 |
Insert Size | 947 bp |
Sequence Data |
>SC211184 3’UTR clone of NM_003824
The sequence shown below is from the reference sequence of NM_003824. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCAGACGCATCTACCTCCGAAGCGTCCTGATGGGCCGCTGCTTTGCGCTGGTGGACCACAGGCATCTAC ACAGCCTGGACTTTGGTTCTCTCCAGGAAGGTAGCCCAGCACTGTGAAGACCCAGCAGGAAGCCAGGCT GAGTGAGCCACAGACCACCTGCTTCTGAACTCAAGCTGCGTTTATTAATGCCTCTCCCGCACCAGGCCG GGCTTGGGCCCTGCACAGATATTTCCATTTCTTCCTCACTATGACACTGAGCAAGATCTTGTCTCCACT AAATGAGCTCCTGCGGGAGTAGTTGGAAAGTTGGAACCGTGTCCAGCACAGAAGGAATCTGTGCAGATG AGCAGTCACACTGTTACTCCACAGCGGAGGAGACCAGCTCAGAGGCCCAGGAATCGGAGCGAAGCAGAG AGGTGGAGAACTGGGATTTGAACCCCCGCCATCCTTCACCAGAGCCCATGCTCAACCACTGTGGCGTTC TGCTGCCCCTGCAGTTGGCAGAAAGGATGTTTTGTCCCATTTCCTTGGAGGCCACCGGGACAGACCTGG ACACTAGGGTCAGGCGGGGTGCTGTGGTGGGGAGAGGCATGGCTGGGGTGGGGGTGGGGAGACCTGGTT GGCCGTGGTCCAGCTCTTGGCCCCTGTGTGAGTTGAGTCTCCTCTCTGAGACTGCTAAGTAGGGGCAGT GATGGTTGCCAGGACGAATTGAGATAATATCTGTGAGGTGCTGATGAGTGATTGACACACAGCACTCTC TAAATCTTCCTTGTGAGGATTATGGGTCCTGCAATTCTACAGTTTCTTACTGTTTTGTATCAAAATCAC TATCTTTCTGATAACAGAATTGCCAAGGCAGCGGGATCTCGTATCTTTAAAAAGCAGTCCTCTTATTCC TAAGGTAATCCTATTAAAACACAGCTTTACAACTTCCATACTACAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_003824.4 |
Synonyms | GIG3; MORT1 |
Summary | The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008] |
Locus ID | 8772 |
MW | 34.9 |
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