Factor XI (F11) (NM_000128) Human 3' UTR Clone

Specifications

Product Data
Product Name	Factor XI (F11) (NM_000128) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	FXI; PTA
ACCN	NM_000128
Insert Size	1097 bp
Sequence Data	Insert Sequence (showhide) >SC212199 3’UTR clone of NM_000128 The sequence shown below is from the reference sequence of NM_000128. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TGGATTCTGGAGAAAACTCAAGCAGTGTGAATGGGTTCCCAGGGGCCATTGGAGTCCCTGAAGGACCCA GGATTTGCTGGGAGAGGGTGTTGAGTTCACTGTGCCAGCATGCTTCCTCCACAGTAACACGCTGAAGGG GCTTGGTGTTTGTAAGAAAATGCTAGAAGAAAACAAACTGTCACAAGTTGTTATGTCCAAAACTCCCGT TCTATGATCGTTGTAGTTTGTTTGAGCATTCAGTCTCTTTGTTTTTGATCACGCTTCTATGGAGTCCAA GAATTACCATAAGGCAATATTTCTGAAGATTACTATATAGGCAGATATAGCAGAAAATAACCAAGTAGT GGCAGTGGGGATCAGGCAGAAGAACTGGTAAAAGAAGCCACCATAAATAGATTTGTTCGATGAAAGATG AAAACTGGAAGAAAGGAGAACAAAGACAGTCTTCACCATTTTGCAGGAATCTACACTCTGCCTATGTGA ACACATTTCTTTTGTAAAGAAAGAAATTGATTGCATTTAATGGCAGATTTTCAGAATAGTCAGGAATTC TTGTCATTTCCATTTTAAAATATATATTAAAAAAAATCAGTTCGAGTAGACACGAGCTAAGAGTGAATG TGAAGATAACAGAATTTCTGTGTGGAAGAGGATTACAAGCAGCAATTTACCTGGAAGTGATACCTTAGG GGCAATCTTGAAGATACACTTTCCTGAAAAATGATTTGTGATGGATTGTATATTTATTTAAAATATCTT GGGAGGGGAGGCTGATGGAGATAGGGAGCATGCTCAAACCTCCCTAAGACAAGCTGCTGCTGTGACTAT GGGCTCCCAAAGAGCTAGATCGTATATTTATTTGACAAAAATCACCATAGACTGCATCCATACTACAGA GAAAAAACAATTAGGGCGCAAATGGATAGTTACAGTAAAGTCTTCAGCAAGCAGCTGCCTGTATTCTAA GCACTGGGATTTTCTGTTTCGTGCAAATATTTATCTCATTATTGTTGTGATCTAGTTCAATAACCTAGA ATTTGAATTGTCACCACATAGCTTTCAATCTGTGCCAACAACTATACAATTCATCAAGTGTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000128.4
Synonyms	FXI; PTA
Summary	This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008]
Locus ID	2160
MW	42.1

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