CD162 (SELPLG) (NM_003006) Human 3' UTR Clone

Specifications

Product Data
Product Name	CD162 (SELPLG) (NM_003006) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD162; CLA; PSGL-1; PSGL1
ACCN	NM_003006
Insert Size	1204 bp
Sequence Data	Insert Sequence (showhide) >SC212994 3’UTR clone of NM_003006 The sequence shown below is from the reference sequence of NM_003006. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACCTCACCCTGCACAGCTTCCTCCCTTAGCTCACTCTGCCATCTGTTTTGGCAAGACCCCACCTCCAC GGGCTCTCCTGGGCCACCCCTGAGTGCCCAGACCCCATTCCACAGCTCTGGGCTTCCTCGGAGACCCCT GGGGATGGGGATCTTCAGGGAAGGAACTCTGGCCACCCAAACAGGACAAGAGCAGCCTGGGGCCAAGCA GACGGGCAAGTGGAGCCACCTCTTTCCTCCCTCCGCGGATGAAGCCCAGCCACATTTCAGCCGAGGTCC AAGGCAGGAGGCCATTTACTTGAGACAGATTCTCTCCTTTTTCCTGTCCCCCATCTTCTCTGGGTCCCT CTAACATCTCCCATGGCTCTCCCCGCTTCTCCTGGTCACTGGAGTCTCCTCCCCATGTACCCAAGGAAG ATGGAGCTCCCCCATCCCACACGCACTGCACTGCCATTGTCTTTTGGTTGCCATGGTCACCAAACAGGA AGTGGACATTCTAAGGGAGGAGTACTGAAGAGTGACGGACTTCTGAGGCTGTTTCCTGCTGCTCCTCTG ACTTGGGGCAGCTTGGGTCTTCTTGGGCACCTCTCTGGGAAAACCCAGGGTGAGGTTCAGCCTGTGAGG GCTGGGATGGGTTTCGTGGGCCCAAGGGCAGACCTTTCTTTGGGACTGTGTGGACCAAGGAGCTTCCAT CTAGTGACAAGTGACCCCCAGCTATCGCCTCTTGCCTTCCCCTGTGGCCACTTTCCAGGGTGGACTCTG TCTTGTTCACTGCAGTATCCCAACTGCAGGTCCAGTGCAGGCAATAAATATGTGATGGACAAACGATAG CGGAATCCTTCAAGGTTTCAAGGCTGTCTCCTTCAGGCAGCCTTCCCGGAATTCTCCATCCCTCAGTGC AGGATGGGGGCTGGTCCTCAGCTGTCTGCCCTCAGCCCCTGGCCCCCCAGGAAGCCTCTTTCATGGGCT GTTAGGTTGACTTCAGTTTTGCCTCTTGGACAACAGGGGGTCTTGTACATCCTTGGGTGACCAGGAAAA GTTCAGGCTATGGGGGGCCAAAGGGAGGGCTGCCCCTTCCCCACCAGTGACCACTTTATTCCACTTCCT CCATTACCCAGTTTTGGCCCACAGAGTTTGGTCCCCCCCAAACCTCGGACCAATATCCCTCTAAACATC AATCTATCCTCCTGTTAAAGAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003006.4
Synonyms	CD162; CLA; PSGL-1; PSGL1
Summary	This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
Locus ID	6404
MW	43.1

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