CD45 (PTPRC) (NM_002838) Human 3' UTR Clone

Specifications

Product Data
Product Name	CD45 (PTPRC) (NM_002838) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200
ACCN	NM_002838
Insert Size	1325 bp
Sequence Data	Insert Sequence (showhide) >SC213395 3’UTR clone of NM_002838 The sequence shown below is from the reference sequence of NM_002838. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCAAGTCCAGCTTTAAATCAAGGTTCATAGGAAAAGACATAAATGAGGAAACTCCAAACCTCCTGTTAG CTGTTATTTCTATTTTTGTAGAAGTAGGAAGTGAAAATAGGTATACAGTGGATTAATTAAATGCAGCGA ACCAATATTTGTAGAAGGGTTATATTTTACTACTGTGGAAAAATATTTAAGATAGTTTTGCCAGAACAG TTTGTACAGACGTATGCTTATTTTAAAATTTTATCTCTTATTCAGTAAAAAACAACTTCTTTGTAATCG TTATGTGTGTATATGTATGTGTGTATGGGTGTGTGTTTGTGTGAGAGACAGAGAAAGAGAGAGAATTCT TTCAAGTGAATCTAAAAGCTTTTGCTTTTCCTTTGTTTTTATGAAGAAAAAATACATTTTATATTAGAA GTGTTAACTTAGCTTGAAGGATCTGTTTTTAAAAATCATAAACTGTGTGCAGACTCAATAAAATCATGT ACATTTCTGAAATGACCTCAAGATGTCCTCCTTGTTCTACTCATATATATCTATCTTATATAGTTTACT ATTTTACTTCTAGAGATAGTACATAAAGGTGGTATGTGTGTGTATGCTACTACAAAAAAGTTGTTAACT AAATTAACATTGGGAAATCTTATATTCCATATATTAGCATTTAGTCCAATGTCTTTTTAAGCTTATTTA ATTAAAAAATTTCCAGTGAGCTTATCATGCTGTCTTTACATGGGGTTTTCAATTTTGCATGCTCGATTA TTCCCTGTACAATATTTAAAATTTATTGCTTGATACTTTTGACAACAAATTAGGTTTTGTACAATTGAA CTTAAATAAATGTCATTAAAATAAATAAATGCAATATGTATTAATATTCATTGTATAAAAATAGAAGAA TACAAACATATTTGTTAAATATTTACATATGAAATTTAATATAGCTATTTTTATGGAATTTTTCATTGA TATGAAAAATATGATATTGCATATGCATAGTTCCCATGTTAAATCCCATTCATAACTTTCATTAAAGCA TTTACTTTGAATTTCTCCAATGCTTAGAATGTTTTTACCAGGAATGGATGTCGCTAATCATAATAAAAT TCAACCATTATTTTTTTCTTGTTTATAATACATTGTGTTATATGTTCAAATATGAAATGTGTATGCACC TATTGAAATATGTTTAATGCATTTATTAACATTTGCAGGACACTTTTACAGGCCCCAATTATCCAATAG TCTAATAATTGTTTAAGATCTAGAAAAAAAAAATCAAGAATAGTGGTATTTTTCATGAAGTAATAAAAA CTCGTTTTGGTGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002838.5
Synonyms	B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200
Summary	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Locus ID	5788
MW	51.8

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