MMP2 (NM_001127891) Human 3' UTR Clone

CAT#: SC213497

3' UTR clone of matrix metallopeptidase 2 (gelatinase A 72kDa gelatinase 72kDa type IV collagenase) (MMP2) transcript variant 2 for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Cited in 1 publication.

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经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name MMP2 (NM_001127891) Human 3' UTR Clone
Vector pMirTarget
Synonyms CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1
ACCN NM_001127891
Insert Size 1279 bp
Sequence Data
>SC213497 3’UTR clone of NM_001127891
The sequence shown below is from the reference sequence of NM_001127891. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
AGCATCAAATCCGACTGGCTAGGCTGCTGAGCTGGCCCTGGCTCCCACAGGCCCTTCCTCTCCACTGCC
TTCGATACACCGGGCCTGGAGAACTAGAGAAGGACCCGGAGGGGCCTGGCAGCCGTGCCTTCAGCTCTA
CAGCTAATCAGCATTCTCACTCCTACCTGGTAATTTAAGATTCCAGAGAGTGGCTCCTCCCGGTGCCCA
AGAATAGATGCTGACTGTACTCCTCCCAGGCGCCCCTTCCCCCTCCAATCCCACCAACCCTCAGAGCCA
CCCCTAAAGAGATACTTTGATATTTTCAACGCAGCCCTGCTTTGGGCTGCCCTGGTGCTGCCACACTTC
AGGCTCTTCTCCTTTCACAACCTTCTGTGGCTCACAGAACCCTTGGAGCCAATGGAGACTGTCTCAAGA
GGGCACTGGTGGCCCGACAGCCTGGCACAGGGCAGTGGGACAGGGCATGGCCAGGTGGCCACTCCAGAC
CCCTGGCTTTTCACTGCTGGCTGCCTTAGAACCTTTCTTACATTAGCAGTTTGCTTTGTATGCACTTTG
TTTTTTTCTTTGGGTCTTGTTTTTTTTTTCCACTTAGAAATTGCATTTCCTGACAGAAGGACTCAGGTT
GTCTGAAGTCACTGCACAGTGCATCTCAGCCCACATAGTGATGGTTCCCCTGTTCACTCTACTTAGCAT
GTCCCTACCGAGTCTCTTCTCCACTGGATGGAGGAAAACCAAGCCGTGGCTTCCCGCTCAGCCCTCCCT
GCCCCTCCCTTCAACCATTCCCCATGGGAAATGTCAACAAGTATGAATAAAGACACCTACTGAGTGGCC
GTGTTTGCCATCTGTTTTAGCAGAGCCTAGACAAGGGCCACAGACCCAGCCAGAAGCGGAAACTTAAAA
AGTCCGAATCTCTGCTCCCTGCAGGGCACAGGTGATGGTGTCTGCTGGAAAGGTCAGAGCTTCCAAAGT
AAACAGCAAGAGAACCTCAGGGAGAGTAAGCTCTAGTCCCTCTGTCCTGTAGAAAGAGCCCTGAAGAAT
CAGCAATTTTGTTGCTTTATTGTGGCATCTGTTCGAGGTTTGCTTCCTCTTTAAGTCTGTTTCTTCATT
AGCAATCATATCAGTTTTAATGCTACTACTAACAATGAACAGTAACAATAATATCCCCCTCAATTAATA
GAGTGCTTTCTATGTGCAAGGCACTTTTCACGTGTCACCTATTTTAACCTTTCCAACCACATAAATAAA
AAAGGCCATTATTAGTTGAATCTTATTGATGAAGAGA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_001127891.3
Synonyms CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1
Summary This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Locus ID 4313
MW 47.9
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Citations (1)

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