CD16 (FCGR3A) (NM_001127596) Human 3' UTR Clone

CAT#: SC213695

3' UTR clone of Fc fragment of IgG low affinity IIIa receptor (CD16a) (FCGR3A) transcript variant 5 for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name CD16 (FCGR3A) (NM_001127596) Human 3' UTR Clone
Vector pMirTarget
Synonyms CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20
ACCN NM_001127596
Insert Size 1283 bp
Sequence Data
>SC213695 3’UTR clone of NM_001127596
The sequence shown below is from the reference sequence of NM_001127596. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
AAATGGAGAAAGGACCCTCAAGACAAATGACCCCCATCCCATGGGGGTAATAAGAGCAGTAGCAGCAGC
ATCTCTGAACATTTCTCTGGATTTGCAACCCCATCATCCTCAGGCCTCTCTACAAGCAGCAGGAAACAT
AGAACTCAGAGCCAGATCCCTTATCCAACTCTCGACTTTTCCTTGGTCTCCAGTGGAAGGGAAAAGCCC
ATGATCTTCAAGCAGGGAAGCCCCAGTGAGTAGCTGCATTCCTAGAAATTGAAGTTTCAGAGCTACACA
AACACTTTTTCTGTCCCAACCGTTCCCTCACAGCAAAGCAACAATACAGGCTAGGGATGGTAATCCTTT
AAACATACAAAAATTGCTCGTGTTATAAATTACCCAGTTTAGAGGGGAAAAAAAAACAATTATTCCTAA
ATAAATGGATAAGTAGAATTAATGGTTGAGGCAGGACCATACAGAGTGTGGGAACTGCTGGGGATCTAG
GGAATTCAGTGGGACCAATGAAAGCATGGCTGAGAAATAGCAGGTAGTCCAGGATAGTCTAAGGGAGGT
GTTCCCATCTGAGCCCAGAGATAAGGGTGTCTTCCTAGAACATTAGCCGTAGTGGAATTAACAGGAAAT
CATGAGGGTGACGTAGAATTGAGTCTTCCAGGGGACTCTATCAGAACTGGACCATCTCCAAGTATATAA
CGATGAGTCCTCTTAATGCTAGGAGTAGAAAATGGTCCTAGGAAGGGGACTGAGGATTGCGGTGGGGGG
TGGGGTGGAAAAGAAAGTACAGAACAAACCCTGTGTCACTGTCCCAAGTTGCTAAGTGAACAGAACTAT
CTCAGCATCAGAATGAGAAAGCCTGAGAAGAAAGAACCAACCACAAGCACACAGGAAGGAAAGCGCAGG
AGGTGAAAATGCTTTCTTGGCCAGGGTAGTAAGAATTAGAGGTTAATGCAGGGACTGTAAAACCACCTT
TTCTGCTTCAATATCTAATTCCTGTGTAGCTTTGTTCATTGCATTTATTAAACAAATGTTGTATAACCA
ATACTAAATGTACTACTGAGCTTCGCTGAGTTAAGTTATGAAACTTTCAAATCCTTCATCATGTCAGTT
CCAATGAGGTGGGGATGGAGAAGACAATTGTTGCTTATGAAAGAAAGCTTTAGCTGTCTCTGTTTTGTA
AGCTTTAAGCGCAACATTTCTTGGTTCCAATAAAGCATTTTACAAGATCTTGCATGCTACTCTTAGATA
GAAGATGGGAAAACCATGGTAATAAAATATGAATGATAAAA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_001127596.2
Synonyms CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20
Summary This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
Locus ID 2214
MW 47.8
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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