HB EGF (HBEGF) (NM_001945) Human 3' UTR Clone

Specifications

Product Data
Product Name	HB EGF (HBEGF) (NM_001945) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DTR; DTS; DTSF; HEGFL
ACCN	NM_001945
Insert Size	1486 bp
Sequence Data	Insert Sequence (showhide) >SC214809 3’UTR clone of NM_001945 The sequence shown below is from the reference sequence of NM_001945. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTGAAGTTGGGCATGACTAATTCCCACTGAGAGAGACTTGTGCTCAAGGAATCGGCTGGGGACTGCTAC CTCTGAGAAGACACAAGGTGATTTCAGACTGCAGAGGGGAAAGACTTCCATCTAGTCACAAAGACTCCT TCGTCCCCAGTTGCCGTCTAGGATTGGGCCTCCCATAATTGCTTTGCCAAAATACCAGAGCCTTCAAGT GCCAAACAGAGTATGTCCGATGGTATCTGGGTAAGAAGAAAGCAAAAGCAAGGGACCTTCATGCCCTTC TGATTCCCCTCCACCAAACCCCACTTCCCCTCATAAGTTTGTTTAAACACTTATCTTCTGGATTAGAAT GCCGGTTAAATTCCATATGCTCCAGGATCTTTGACTGAAAAAAAAAAAGAAGAAGAAGAAGGAGAGCAA GAAGGAAAGATTTGTGAACTGGAAGAAAGCAACAAAGATTGAGAAGCCATGTACTCAAGTACCACCAAG GGATCTGCCATTGGGACCCTCCAGTGCTGGATTTGATGAGTTAACTGTGAAATACCACAAGCCTGAGAA CTGAATTTTGGGACTTCTACCCAGATGGAAAAATAACAACTATTTTTGTTGTTGTTGTTTGTAAATGCC TCTTAAATTATATATTTATTTTATTCTATGTATGTTAATTTATTTAGTTTTTAACAATCTAACAATAAT ATTTCAAGTGCCTAGACTGTTACTTTGGCAATTTCCTGGCCCTCCACTCCTCATCCCCACAATCTGGCT TAGTGCCACCCACCTTTGCCACAAAGCTAGGATGGTTCTGTGACCCATCTGTAGTAATTTATTGTCTGT CTACATTTCTGCAGATCTTCCGTGGTCAGAGTGCCACTGCGGGAGCTCTGTATGGTCAGGATGTAGGGG TTAACTTGGTCAGAGCCACTCTATGAGTTGGACTTCAGTCTTGCCTAGGCGATTTTGTCTACCATTTGT GTTTTGAAAGCCCAAGGTGCTGATGTCAAAGTGTAACAGATATCAGTGTCTCCCCGTGTCCTCTCCCTG CCAAGTCTCAGAAGAGGTTGGGCTTCCATGCCTGTAGCTTTCCTGGTCCCTCACCCCCATGGCCCCAGG CCCACAGCGTGGGAACTCACTTTCCCTTGTGTCAAGACATTTCTCTAACTCCTGCCATTCTTCTGGTGC TACTCCATGCAGGGGTCAGTGCAGCAGAGGACAGTCTGGAGAAGGTATTAGCAAAGCAAAAGGCTGAGA AGGAACAGGGAACATTGGAGCTGACTGTTCTTGGTAACTGATTACCTGCCAATTGCTACCGAGAAGGTT GGAGGTGGGGAAGGCTTTGTATAATCCCACCCACCTCACCAAAACGATGAAGTTATGCTGTCATGGTCC TTTCTGGAAGTTTCTGGTGCCATTTCTGAACTGTTACAACTTGTATTTCCAAACCTGGTTCATATTTAT ACTTTGCAATCCAAATAAAGATAACCCTTATTCCATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001945.3
Synonyms	DTR; DTS; DTSF; HEGFL
Summary	Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB/Swiss-Prot Function]
Locus ID	1839
MW	56.1

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