TMEM16A (ANO1) (NM_018043) Human 3' UTR Clone
CAT#: SC215210
3' UTR clone of anoctamin 1 calcium activated chloride channel (ANO1) for miRNA target validation
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CNY 5,795.00
货期*
3周
规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | TMEM16A (ANO1) (NM_018043) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | DOG1; ORAOV2; TAOS2; TMEM16A |
ACCN | NM_018043 |
Insert Size | 1556 bp |
Sequence Data |
>SC215210 3’UTR clone of NM_018043
The sequence shown below is from the reference sequence of NM_018043. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCCATGCCTACCACGGGGGCGTCCTGTAGCTATGCCAGCGGGGCTGGGCAGGCCAGCCGGGCATCCTG ACCGATGGGCACCCTCTCCCAGGGCAGGCGGCTTCCCGCTCCCACCAGGGCCCGGTGGGTCCTGGGTTT TCTGCAAACATGGAGGACCACTTTCTGATAGGACATTTTCCTTTCTTCTTTCTGTTTTCTTTCCCTTGT TTTTGCACAAAGCCATTATGCAGGGAATATTTTTTAATCTGTAGTATTCAAGATGAATCAAAATGATGG CTGGTAATACGGCAATAAGGTAGCAAAGGCAGGTGCTTTGCAGAAAGAATGCTTGGAAACTTGAGTCTC CCTAGAGGTGAAAAGTGAGCAGAGGCCCGTAGAAACCCTCCTCTGAATCCTCCTAATTCCTTAAGATAG ATGCAAAATGGTAAGCCGAGGCATCGCGCAAAAGCTGGTGCGATGCTTCAGGGAAAATGGAAAACCCAC GCAAGAATAATGATTGATTCCGGTTCCAAAAGGTGTCACCTACCTGTTTCAGAAAAGTTAGACTTTCCA TCGCCTTTTCCTTCCATCAGTTGAGTGGCTGAGAGAGAAGTGCCTCATCCCTGAGCCACACAGGGGGCG TGGGAGCATCCCAGTTATCCCTGGAAAGCTAGAAGGGGACAGAGGTGTCCCTGATTAAGCAGGAAACAG CACCCTTGGCGTCCCCAGCAGGCTCCCCACTGTCAGCCACACACCTGCCCCCATCACACCAAGCCGACC TCAGAGTTGTTCATCTTCCTTATGGGACAAAACCGGTTGACCAGAAAATGGGCAGAGAGAGATGACCTC GGAAGCATTTCCACAGATGGTGTCAGGGTTTCAAGAAGTCTTAGGGCTTCCAGGGGTCCCCTGGAAGCT TTAGAATATTTATGGGTTTTTTTTCAAATATCAATTATATGGTAGATTGAGGATTTTTTTTCTGTAGCT CAAAGGTGGAGGGAGTTTATTAGTTAACCAAATATCGTTGAGAGGAATTTAAAATACTGTTACTACCAA AGATTTTTATTAATAAAGGCTTATATTTTGGTAACACTTCTCTATATTTTTACTCACAGGAATGTCACT GTTGGACAATTATTTTAAAAGTGTATAAAACCAAGTCTCATAAATGATATGAGTGATCTAAATTTGCAG CAATGATACTAAACAACTCTCTGAAATTTCTCAAGCACCAAGAGAAACATCATTTTAGCAAAGGCCAGG AGGAAAAATAGAAATAAATTTGTCTTGAAGATCTCATTGATGTGATGTTACATTCCCTTTAATCTGCCA ACTGTGGTCAAAGTTCATAGGTGTCGTACATTTCCATTATTTGCTAAAATCATGCAATCTGATGCTTCT CTTTTCTCTTGTACAGTAAGTAGTTTGAAGTGGGTTTTGTATATAAATACTGTATTAAAAATTAGGCAA TTACCAAAAATCCTTTTATGGAAACCATTTTTTTAAAAAGTGAATGTACACAAATCCACAGAGGACTGT GGCTGGACATTCATCTAAATAAATTTGAATATACGACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_018043.7 |
Synonyms | DOG1; ORAOV2; TAOS2; TMEM16A |
Summary | Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.[UniProtKB/Swiss-Prot Function] |
Locus ID | 55107 |
MW | 59.9 |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology
,Sonneville, F;Ruffin, M;Coraux, C;Rousselet, N;Le Rouzic, P;Blouquit-Laye, S;Corvol, H;Tabary, O;,
Nat Commun
,PubMed ID 28955034
[TMEM16A]
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