ALS2 (NM_020919) Human 3' UTR Clone

Specifications

Product Data
Product Name	ALS2 (NM_020919) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ALS2CR6; ALSJ; IAHSP; PLSJ
ACCN	NM_020919
Insert Size	1614 bp
Sequence Data	Insert Sequence (showhide) >SC215560 3’UTR clone of NM_020919 The sequence shown below is from the reference sequence of NM_020919. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACCAGATTCAGCGTGAGAAGCTTAACTAGGCTGCATAACAGCTTGAAAACTGGATTATCTACTACAGA GTGTTATAACACCATCTGGAGTCTTCCTGTAGTGGCAAAAAAGAACAGTGTTGAAATTGGAAAGGACTT TGTGTTATTTAGGTTGTTAGAATGAGCCTTACCAATAATAAGAGCCCTGAGCCCAGAAAAAAGGACTGT ATAGTTTAAAGGGAGGATTGAAAGGGAGGTAAAAAATCAGATTAGACCAGTTCTTGGCCTATGATAAGT TCCAAAAATACCATTTATCTACTATTTGAAAAAAGAAGAGGATATCCCTTCCTACAGTAAAGGGTATGT CAGCTACATGAAGTTGTAAGAAAAGCTTCCAGTAGAGCTTCTTATATTAAAGAAGTTGATGGATATTTT TGAATTTCTGGTTTGCCTGAATCCACCTGCAGTTACCCCGATCCGTTTGCAAGAACCAGATCGTACTTG AAACTATAGTGGCCACACTCTGCCTTCCTGAGTCCCTTCCAGTCATGTGTGCATCATGTCTCTTTGCCA AGGGAGGGGAGAAAGGAACTTTTAAACTGCAGTTTTAACTTTTTCTAAGCTGTTTCTTGATGGGAGAGG TTCTGTGCAAAACTACCACATTCTGTCCCCAAAATGTGGAATGCATCCAAATAGGAGTCTTCTGCCTCT TAACTTAAAAGAACATAGGAATTTTGTTTTTGGTTTCTTTATCATGCTACAGAGAGTGAATACACTGGA ATTCAGACACCGACTCTGAGCTGCTAGGAACCTCATTTGTCCATGTGCAAACGCTGTATTCCAAGGCCT GTGAATGGCAGCCTGAGGAAGTTTTGCATGCAGGCTGTGTTTTCGAGCAGGACTAACAACTGGGAAATA AGCAAAAAACTGCATCGATCCCCAGCCTGGTGTTGTTCTTCCCTATACTTCACACTGAACTCAGGATGG GAAGAAAAAGGAAACAAGCTTTGGCTTTTTCCATCTCAAAAGTATTGTGGCACCTCAACATTTCAGTGT TTTGCTTTTTAAAAAATGCCCTATTGTAAGTTGTTGGTTTATACTGTATAAGTAACACTAGTAGCTGTT TTGAATAACATAGGTGCTCTTCCTCATCTCATCTCCTACACCGTGGTGAGCATACAGAGTGTCCTGATT TGTGTTAAGTGACTGAGAAGATGTTAATTACTTTTGAAAAAGGATCATGGTTTTTGCTCTACTTTATAA TCAAGACAAGTGTTTATTAAAATACTGTTTTGGAATGTTGGCTGTAATGTAACAGCAATTTTCATAATA AAAGGCATTCATCTTTATGTGGTTGTTTTATGATTGTAGAAGAAATGAACAGGGCAGCCTAAAAGATGA AAGGAAACCCAGACTTAGTATTTCTTTAGCCCACATTGTAATCCATGCCTCTAAGTATTGGCCTCAAAA GTCCCTCTGGGGTTTTAGAAATCTCTGTCTTTAAAATAAACGTAAACCAATAGTTATAGCACCCTTTCT AGCAAAGAGCAAATTAACTTTCTGACCCCAATAACCCAAGGACACGGGTCTCCAAAGAAATCTATTATT TCTTTGAATAAAAAGCATATTTTGATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_020919.4
Synonyms	ALS2CR6; ALSJ; IAHSP; PLSJ
Summary	The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Locus ID	57679
MW	61.9

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.