FBXW7 (NM_018315) Human 3' UTR Clone

CAT#: SC215767

3' UTR clone of F-box and WD repeat domain containing 7 (FBXW7) transcript variant 2 for miRNA target validation



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CNY 5,795.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name FBXW7 (NM_018315) Human 3' UTR Clone
Vector pMirTarget
Synonyms AGO; CDC4; FBW6; FBW7; FBX30; FBXO30; FBXW6; hAgo; hCdc4; SEL-10; SEL10
ACCN NM_018315
Insert Size 2000 bp
Sequence Data
>SC215767 3’UTR clone of NM_018315
The sequence shown below is from the reference sequence of NM_018315. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
GTGCTGGACTTTGATGTGGACATGAAGTGAAGAGCAGAAAAGATGAATTTGTCCAATTGTGTAGACGAT
ATACTCCCTGCCCTTCCCCCTGCAAAAAGAAAAAAAGAAAAGAAAAAGAAAAAAATCCCTTGTTCTCAG
TGGTGCAGGATGTTGGCTTGGGGCAACAGATTGAAAAGACCTACAGACTAAGAAGGAAAAGAAGAAGAG
ATGACAAACCATAACTGACAAGAGAGGCGTCTGCTGTCTCATCACATAAAAGGCTTCACTTTTGACTGA
GGGCAGCTTTGCAAAATGAGACTTTCTAAATCAAACCAGGTGCAATTATTTCTTTATTTTCTTCTCCAG
TGGTCATTGGGCAGTGTTAATGCTGAAACATCATTACAGATTCTGCTAGCCTGTTCTTTTACCACTGAC
AGCTAGACACCTAGAAAGGAACTGCAATAATATCAAAACAAGTACTGGTTGACTTTCTAATTAGAGAGC
ATCTGCAACAAAAAGTCATTTTTCTGGAGTGGAAAAGCTTAAAAAAATTACTGTGAATTGTTTTTGTAC
AGTTATCATGAAAAGCTTTTTTTTTTTTTTTTTTGCCAACCATTGCCAATGTCAATCAATCACAGTATT
AGCCTCTGTTAATCTATTTACTGTTGCTTCCATATACATTCTTCAATGCATATGTTGCTCAAAGGTGGC
AAGTTGTCCTGGGTTCTGTGAGTCCTGAGATGGATTTAATTCTTGATGCTGGTGCTAGAAGTAGGTCTT
CAAATATGGGATTGTTGTCCCAACCCTGTACTGTACTCCCAGTGGCCAAACTTATTTATGCTGCTAAAT
GAAAGAAAGAAAAAAGCAAATTATTTTTTTTTATTTTTTTTCTGCTGTGACGTTTTAGTCCCAGACTGA
ATTCCAAATTTGCTCTAGTTTGGTTATGGAAAAAAGACTTTTTGCCACTGAAACTTGAGCCATCTGTGC
CTCTAAGAGGCTGAGAATGGAAGAGTTTCAGATAATAAAGAGTGAAGTTTGCCTGCAAGTAAAGAATTG
AGAGTGTGTGCAAAGCTTATTTTCTTTTATCTGGGCAAAAATTAAAACACATTCCTTGGAACAGAGCTA
TTACTTGCCTGTTCTGTGGAGAAACTTTTCTTTTTGAGGGCTGTGGTGAATGGATGAACGTACATCGTA
AAACTGACAAAATATTTTAAAAATATATAAAACACAAAATTAAAATAAAGTTGCTGGTCAGTCTTAGTG
TTTTACAGTATTTGGGAAAACAACTGTTACAGTTTTATTGCTCTGAGTAACTGACAAAGCAGAAACTAT
TCAGTTTTTGTAGTAAAGGCGTCACATGCAAACAAACAAAATGAATGAAACAGTCAAATGGTTTGCCTC
ATTCTCCAAGAGCCACAACTCAAGCTGAACTGTGAAAGTGGTTTAACACTGTATCCTAGGCGATCTTTT
TTCCTCCTTCTGTTTATTTTTTTGTTTGTTTTATTTATAGTCTGATTTAAAACAATCAGATTCAAGTTG
GTTAATTTTAGTTATGTAACAACCTGACATGATGGAGGAAAACAACCTTTAAAGGGATTGTGTCTATGG
TTTGATTCACTTAGAAATTTTATTTTCTTATAACTTAAGTGCAATAAAATGTGTTTTTTCATGTTAGTA
TGCCTGTTTCTTCCACTGAAGTAATAATCCTTCATTATAAGTATTTAGGATTTGTCTATAATATTTAAA
TAAGCAAAATCTTGGTTTCTTTGCATCCTGCTGTGTGACATAGAAATCAATACTTCAAGCCTGTTTTAT
ACCGCGAAAGTAAGGATAATGTGCTGCAACTGCAAATTTTATTTCTCTCCTAGACTATGAAGGAGGACA
CTCCACTGTGCTCATCTCTGTAGATTGCATTGGGGTGTATAAATATGAAATCTGGTTCCCTCAAAGAAT
CCACAAAACTTTTGTGATAATTACAACTAGAAGCCTTATAAATAACAAATTCATTTTGAAATTTTGAC
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_018315.5
Synonyms AGO; CDC4; FBW6; FBW7; FBX30; FBXO30; FBXW6; hAgo; hCdc4; SEL-10; SEL10
Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Locus ID 55294
MW 78.4
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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