TLR7 (NM_016562) Human 3' UTR Clone

Specifications

Product Data
Product Name	TLR7 (NM_016562) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	IMD74; TLR7-like
ACCN	NM_016562
Insert Size	1733 bp
Sequence Data	Insert Sequence (showhide) >SC216098 3’UTR clone of NM_016562 The sequence shown below is from the reference sequence of NM_016562. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TATAGTCAGGTGTTCAAGGAAACGGTCTAGCCCTTCTTTGCAAAACACAACTGCCTAGTTTACCAAGGA GAGGCCTGGCTGTTTAAATTGTTTTCATATATATCACACCAAAAGCGTGTTTTGAAATTCTTCAAGAAA TGAGATTGCCCATATTTCAGGGGAGCCACCAACGTCTGTCACAGGAGTTGGAAAGATGGGGTTTATATA ATGCATCAAGTCTTCTTTCTTATCTCTCTGTGTCTCTATTTGCACTTGAGTCTCTCACCTCAGCTCCTG TAAAAGAGTGGCAAGTAAAAAACATGGGGCTCTGATTCTCCTGTAATTGTGATAATTAAATATACACAC AATCATGACATTGAGAAGAACTGCATTTCTACCCTTAAAAAGTACTGGTATATACAGAAATAGGGTTAA AAAAAACTCAAGCTCTCTCTATATGAGACCAAAATGTACTAGAGTTAGTTTAGTGAAATAAAAAACCAG TCAGCTGGCCGGGCATGGTGGCTCATGCTTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCA CGAGGTCAGGAGTTTGAGACCAGTCTGGCCAACATGGTGAAACCCCGTCTGTACTAAAAATACAAAAAT TAGCTGGGCGTGGTGGTGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGA ACCCGGGAGGTGGAGGTGGCAGTGAGCCGAGATCACGCCACTGCAATGCAGCCCGGGCAACAGAGCTAG ACTGTCTCAAAAGAACAAAAAAAAAAAAACACAAAAAAACTCAGTCAGCTTCTTAACCAATTGCTTCCG TGTCATCCAGGGCCCCATTCTGTGCAGATTGAGTGTGGGCACCACACAGGTGGTTGCTGCTTCAGTGCT TCCTGCTCTTTTTCCTTGGGCCTGCTTCTGGGTTCCATAGGGAAACAGTAAGAAAGAAAGACACATCCT TACCATAAATGCATATGGTCCACCTACAAATAGAAAAATATTTAAATGATCTGCCTTTATACAAAGTGA TATTCTCTACCTTTGATAATTTACCTGCTTAAATGTTTTTATCTGCACTGCAAAGTACTGTATCCAAAG TAAAATTTCCTCATCCAATATCTTTCAAACTGTTTTGTTAACTAATGCCATATATTTGTAAGTATCTGC ACACTTGATACAGCAACGTTAGATGGTTTTGATGGTAAACCCTAAAGGAGGACTCCAAGAGTGTGTATT TATTTATAGTTTTATCAGAGATGACAATTATTTGAATGCCAATTATATGGATTCCTTTCATTTTTTGCT GGAGGATGGGAGAAGAAACCAAAGTTTATAGACCTTCACATTGAGAAAGCTTCAGTTTTGAACTTCAGC TATCAGATTCAAAAACAACAGAAAGAACCAAGACATTCTTAAGATGCCTGTACTTTCAGCTGGGTATAA ATTCATGAGTTCAAAGATTGAAACCTGACCAATTTGCTTTATTTCATGGAAGAAGTGATCTACAAAGGT GTTTGTGCCATTTGGAAAACAGCGTGCATGTGTTCAAGCCTTAGATTGGCGATGTCGTATTTTCCTCAC GTGTGGCAATGCCAAAGGCTTTACTTTACCTGTGAGTACACACTATATGAATTATTTCCAACGTACATT TAATCAATAAGGGTCACAAATTCCCAAATCAATCTCTGGAATAAATAGAGAGGTAATTAAATTGCTGGA GCCAACTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_016562.4
Synonyms	IMD74; TLR7-like
Summary	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. The human TLR family comprises 11 members. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. For the recognition of structural components in foreign microorganisms, the various TLRs exhibit different patterns of expression as well; in this way for example, TLR-3, -7, and -8 are essential in the recognition of single-stranded RNA viruses. TLR7 senses single-stranded RNA oligonucleotides containing guanosine- and uridine-rich sequences from RNA viruses, a recognition occuring in the endosomes of plasmacytoid dendritic cells and B cells. This gene is predominantly expressed in lung, placenta, and spleen, and is phylogenetically related and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Aug 2020]
Locus ID	51284
MW	67.1

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