SH2D1A (NM_001114937) Human 3' UTR Clone
CAT#: SC216406
3' UTR clone of SH2 domain protein 1A (SH2D1A) transcript variant 2 for miRNA target validation
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CNY 5,795.00
货期*
3周
规格
Product images
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经常一起买 (2)
Specifications
Product Data | |
Product Name | SH2D1A (NM_001114937) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | DSHP; EBVS; IMD5; LYP; MTCP1; SAP; SAP/SH2D1A; XLP; XLPD; XLPD1 |
ACCN | NM_001114937 |
Insert Size | 1799 bp |
Sequence Data |
>SC216406 3’UTR clone of NM_001114937
The sequence shown below is from the reference sequence of NM_001114937. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GATCCTGATGTCTGCCTGAAAGCCCCATGAAGAAAAATAAAACACCTTGTACTTTATTTTCTATAATTT AAATATATGCTAAGTCTTATATATTGTAGATAATACAGTTCGGTGAGCTACAAATGCATTTCTAAAGCC ATTGTAGTCCTGTAATGGAAGCATCTAGCATGTCGTCAAAGCTGAAATGGACTTTTGTACATAGTGAGG AGCTTTGAAACGAGGATTGGGAAAAAGTAATTCCGTAGGTTATTTTCAGTTATTATATTTACAAATGGG AAACAAAAGGATAATGAATACTTTATAAAGGATTAATGTCAATTCTTGCCAAATATAAATAAAAATAAT CCTCAGTTTTTGTGAAAAGCTCCATTTTTAGTGAAATATTATTTTATAGCTACTAATTTTAAAATGTCT TGCTTGATTGTATGGTGGGAAGTTGGCTGGTGTCCCTTGTCTTTGCCAAGTTCTCCACTAGCTATGGTG TCATAGGCTCTTTTGGGATTTTTGAAGCTGTATACTGTGTGCTAAAACAAGCACTAAACAAAGAGTGAA GGATTTATGTTTAATTCTGAAAGCAACCTTCTTGCCTAGTGTTCTGATATTGGACAGTAAAATCCACAG ACCAACCTGGAGTTGAAAATCTTATAATTTAAAATATGCTCTAAACATGTTTATCGTATTTGATGCTAC AGGATTTGAAATTGTATTACAAATCCAATGAAATGAGTTTTTCTTTTCATTTACCTCTGCCCCAGTTGT TTCTACTACATGGAAGACCTCATTTTGAAGGGAAATTTCAGCAGCTGCAGCTCATGAGTAACTGATTTG TAACAAGCCTCCTTTTAAAGTAACCCTACAAAACCACTGGAAAGTTTATGGTTGTATTATTTTTTAAAA AAATTCCAAGTGATTGAAACCTACACGAGATACAGAATTTTATGCGGCATTTTCTTCTCACATTTATAT TTTTGTGATTTTGTGATTGATTATATGTCACTTTGCTACAGGGCTCACAGAATTCATTCACTCAACAAA CATAATAGGGCGCTGAGGGCATAGAAGTAAAAACACCTGGTCCCTGCTCTCAGTTCACTGTCTTGTTGG ACGAGAAAACAATAACGATAAAAGACAGTGAAAGAAAATAACGATAAAAGACAGTGAAAGAAAATAACA ATAAAAGACAAGGAAAAAATAACAATGAAAGTTGATAAGTACATGATAAGCGAGGTTCCCCGTGTGTAG GTAGATCTGGTCTTTAGAGGCAGATAGATAGGTCAGTGCAAATACTCTGGTCCATGGGCCATATGAAAA GGCTAAGCTTCACTGTAAAATAATAACTGGGAATTCTGGATTGTGTATGGGTGTTGGTGAACTTGGTTT TAATTAGTGAACTGCTGAGAGACAGAGCTATTCTCCATGTACTGGCAAGACCTGATTTCTGAGCATTTA ATATGGATGCCGTGGGAGTACAAAAGTGGAGTGTGGCCTGAGTAATGCATTATGGGTGGTTTACCATTT CTTGAGGTAAAAGCATCACATGAACTTGTAAAGGAATTTAAAAATCCTACTTTCATAATAAGTTGCATA GGTTTAATAATTTTTAATTATATGGCTTGAGTTTAAATTGTAATAGGCGTAACTAATTTTAACTCTATA ATGTGTTCATTCTGGAATAATCCTAAACATATGAATTATGTTTGCATGTTCACTTCCAAGAGCCTTTTT TTGAAAAAAAGCTTTTTTTGAATCATCAAGTCTTTCACATTTAAATAAAGTGTTTGAAAGCTTTATTTA CCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001114937.3 |
Synonyms | DSHP; EBVS; IMD5; LYP; MTCP1; SAP; SAP/SH2D1A; XLP; XLPD; XLPD1 |
Summary | This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Locus ID | 4068 |
MW | 70.7 |
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