Methionine Aminopeptidase 2 (METAP2) (NM_006838) Human 3' UTR Clone

Specifications

Product Data
Product Name	Methionine Aminopeptidase 2 (METAP2) (NM_006838) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MAP2; MNPEP; p67eIF2
ACCN	NM_006838
Insert Size	1965 bp
Sequence Data	Insert Sequence (showhide) >SC217097 3’UTR clone of NM_006838 The sequence shown below is from the reference sequence of NM_006838. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAGTTGTCAGCAGAGGAGATGACTATTAAACTTAGTCCAAAGCCACCTCAACACCTTTATTTTCTGAG CTTTGTTGGAAAACATGATACCAGAATTAATTTGCCACATGTTGTCTGTTTTAACAGTGGACCCATGTA ATACTTTTATCCATGTTTAAAAAAGAAGGAATTTGGACAAAGGCAAACCGTCTAATGTAATTAACCAAC GAAAAAGCTTTCCGGACTTTTAAATGCTAACTGTTTTTCCCCTTCCTGTCTAGGAAAATGCTATAAAGC TCAAATTAGTTAGGAATGACTTATACGTTTTGTTTTGAATACCTAAGAGATACTTTTTGGATATTTATA TTGCCATATTCTTACTTGAATGCTTTGAATGACTACATCCAGTTCTGCACCTATACCCTCTGGTGTTGC TTTTTAACCTTCCTGGAATCCATTTTCTAAAAAATAAAGACATTTTCAGATCTGAGAGCTACATCTCAA TGTCTGTGGTTATAATTCTGGACAGGATAAATAGCTAAACTTAATGTAGGCAAATGCAGAGACATTTAT CTGAAATGTAGACCTCTACACTGAGACTTTTCTGGCATAGTGGCTAAAACAAGATCTACACATGCATAA AAAGGGACAATCACCTTTTCTTCATAAATATACAGCTTTAGGAATATTTCACCATTCTTTGTAGGACAT AGTAGTCCTTGTCTTTTTTTCTCCTGACATTGGAAAGATGTGCTAATTGAAACTTGACTTAGTAGGAAC ATTGTGCCAACTCAAAACCTTGATTTAGTAAAAATCTCAATGTTTAGATCCTTTGTCCAGTGGTGGTGT TTATCAGGGAATGTATTCAGCTTGCTCAGAAAACCAAAAGGGTATTAAAGCCACAAAAGCAAAGAAGAA AAAAAAAAACTTCCCATGTTTGGATCTTGTTCTAGTTAGAAAAATTAAGTTGAAATTCTTGGACTTTTT CATTCATGAGGCAAATGCTGTAATACCTTCCCCTTTGACAGGTTTGGATTCTTAACATTACTAGTGGTA TTTCAGGAAGTGACGTTACAGTTACTTTCCTTATAGCGGCTAAGTGTATTAAGTTGAATGTAACGATGG TAATATTAATTTGTTTGAACTGAGGCCCACTACTGATTCTTTGACAAATTGAATTCTTATATTTAAATA ATTTTATGGGAATGTTCCATCATAATTTCTAAATCATTTATATATCAAGGTAGCCTTAATTTGTATATG TTTCAGTACAATGAGATTTTATTGCCTCTGGGATGCTGTTTAGTTTGTATTTTGTTGAACGTTTTTATC CTAGGAAGAGAAACCTATGACTTGTGTACCTAGATCATCTGTTACATTAAAAAGCTGCTCTTTCAGCAT TAGAGCTATAAATGAATGTTACCTTGTCGGGAAACAATCTAGGTTTTAGCTGTATGAGCTATGTTTATT ATGGTGCTAATGTTCAGTAGCCACATTTGACTAATGTCTCCATTCTCTGTGATGCTGTGGCTAGCAGCA GAGCTCGCCAGTTCATGCCTGGACATACTGTCAGGGCTGGGCCCTCCAGCTAGCTCCTTTGGGGTTGAG TCCGTATCTTTTTGATGTGGAAGTATAAAGCAAGTATCTTGATTTCTAAACCCAGCAATTTTAGAATTG ACCTTTATGAGTGAAGACTTTTGGAGCTTTTAAAGACCTTGGCAGTCATGATCTCAAACCAATTAGGAG CTCCAAGCTCCCTTCCCAGGTAACTGTTGGGAGCAATGGCATCACTGTATGCCCTTGTAATGGCTGGAA GGGACATGATCTTGTAAGTAGGAAAGCTGTAACTAAAAATTGTATTGTTTGCTTATTAGCCATGTATCT CTTAAAATTTTGTTATGTTTACAACGATGTACCTTATTGGCAACAAGTTATTAGTTTGATGTTTAACAA TAGTGCCTTTAGTAAATTATTTTACAACTAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006838.4
Synonyms	MAP2; MNPEP; p67eIF2
Summary	The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Locus ID	10988
MW	76.2

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