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Hmgb3 (NM_008253) Mouse Untagged Clone
CAT＃: MC202547
Hmgb3 (untagged) - Mouse high mobility group box 3 (Hmgb3), (10ug)
CNY 2,400.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Hmg2a; Hmg4 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC083352 sequence for NM_008253
ATACAGTCAGGATGGCTAAAGGTGACCCCAAGAAACCAAAGGGCAAGATGTCTGCTTATGCCTTCTTTGT GCAGACATGCAGGGAAGAACATAAGAAGAAAAACCCAGAGGTTCCCGTCAATTTTGCTGAGTTCTCCAAG AAGTGCTCGGAGAGGTGGAAGACCATGTCTAGCAAAGAGAAATCAAAGTTTGATGAAATGGCAAAGGCAG ATAAAGTCCGATATGATCGGGAGATGAAAGATTATGGACCAGCTAAAGGAGGCAAGAAGAAGAAGGACCC AAATGCCCCCAAAAGACCTCCGTCTGGATTTTTCTTATTCTGCTCTGAATTCCGCCCCAAGATCAAATCC ACAAACCCTGGCATCTCCATTGGAGATGTGGCAAAAAAGCTGGGTGAGATGTGGAATAACTTAAGTGACA ATGAAAAGCAGCCTTATGTCACCAAGGCAGCAAAGCTGAAGGAGAAGTATGAGAAGGATGTTGCTGACTA TAAGTCTAAAGGGAAGTTTGATGGTGCCAAGGGTCCTGCTAAAGTTGCCCGGAAAAAGGTGGAAGAAGAG GAAGAGGAGGAGGAAGAGGAAGAAGAGGAGGAGGAAGAGGAGGAAGATGAATAAAAGCTCTGTCTCCTTG TGAATACCTTAGAGTAGGAGAGCGCTGTGATTGACACATCTCTTATTTGAGTCGTGTCTATTGCCCTTGT TAGGTTTAATTACAAAATTTGATCACGATCATATTGTAGTTTCTCAAAGTGTCAGTGGTTTACATGAAGT GGCCGTGGGTGTCCGGAGCGCCCTGAAACTGTATCAAAGTTGTACATAGCTCCAAACATTTTTAAAATGA AAAGGCACTCTCGCGTCCTCCTCACTCAGTGCACTTTGCTGTTGGTGTGACAAGGCATTTGAAGATGTTT CTGGCATTTTGTTCTCAACTCGTAAGGTAGTGTTAACTATATGGTTATTGGCTAGCAATCCTGAGTTGTC AACTGTACATATCTATAGTTTGTAAAGAGAATGAAACAACCCAGACAGATTCTTGATGCTCCTTGTTTGG CGTGGAGGCTGTGAGGGGAAGATGCCTTTTGGAGGGGGCCGTAGCTCAGGGCGTGCACTGTGAGGCTGGA CCTGTTGATACTGCGGTGGGCATCCATTTAGCTTCAGGTTGTCCTGTGTTTGTATATAGTGGCATAGCAT TCTGCTGACATTCTTAGTTGTGGAAAGGGGGGAGGGGTCGGCCGGCATGAGAAGTGTTTGGAGTTTTTTC TTTAGTTAAGTGCAGTAGGTTTGAAACTTTTTAAAGAAACTGTAGGACTCATCATTGTCAGCAAAGCAAA GAACTACTGCATCAATGGAAGTTCAAGAACCCTCTGGACCTAAACGCAATTTGCAACATTCTGTTATTTT TTGTATGTTTAGAATGCTGAAATGTTTTTGAAGTTAAATAAACAGTATTACATTTTTAAAACTGAAAAAA AAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | NM_008253 |
| Insert Size | 603 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC083352, AAH83352 |
| RefSeq Size | 1490 bp |
| RefSeq ORF | 603 bp |
| Locus ID | 15354 |
| UniProt ID | O54879 |
| Gene Summary | Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (PubMed:19890330). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (PubMed:12714519, PubMed:15358624, PubMed:16945912).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, and 4 encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG202042 | Hmgb3 (tGFP-tagged) - Mouse high mobility group box 3 (Hmgb3) |
CNY 2,850.00 |
|
| MR202042 | Hmgb3 (Myc-DDK-tagged) - Mouse high mobility group box 3 (Hmgb3) |
CNY 2,400.00 |
|
| MR202042L3 | Lenti ORF clone of Hmgb3 (Myc-DDK-tagged) - Mouse high mobility group box 3 (Hmgb3) |
CNY 4,750.00 |
|
| MR202042L4 | Lenti ORF clone of Hmgb3 (mGFP-tagged) - Mouse high mobility group box 3 (Hmgb3) |
CNY 4,750.00 |
