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Sdcbp (NM_016807) Mouse Untagged Clone
CAT＃: MC203905
Sdcbp (untagged) - Mouse syndecan binding protein (Sdcbp), transcript variant 2, (10ug)
CNY 2,400.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | MDA-9; Sycl; syntenin-1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC019400
TGGAGCTGGAGCGGGCAGCAGGAGAGCGCGGTCCTCGGGGCAGAAAATATCTGCAGAAATGTCTCTTTAT CCATCTCTTGAAGATTTGAAGGTAGACAAAGTAATTCAGGCTCAAACTGCTTATTCTGCCAATCCCGCCA GCCAAGCATTTGTTCTGGTGGATGCTTCTGCTGCTCTTCCTCCAGATGGAAATCTGTATCCTAAACTGTA TCCAGAGCTCTCTCAATACATGGGACTGTCTTTAAATGAAGCTGAAATATGTGAGAGCATGCCCATGGTC TCTGGAGCACCAGCACAAGGGCAGTTGGTAGCAAGACCATCCAGTGTGAACTATATGGTAGCACCTGTGA CAGGTAACGATGCTGGAATTCGGAGAGCAGAAATTAAGCAAGGGATTCGTGAAGTTATTTTGTGTAAGGA TCAAGATGGAAAAATTGGGCTCAGACTTAAGTCAATAGATAATGGTATATTTGTTCAACTCGTCCAGGCT AATTCCCCAGCCTCCTTGGTTGGACTGAGATTTGGGGACCAGGTGCTCCAGATCAACGGTGAAAACTGTG CGGGCTGGAGCTCTGATAAGGCACACAAGGTGCTCAAGCAGGCGTTTGGAGAGAAGATCACCATGACGAT CCGTGACAGGCCCTTTGAACGGACAGTTACTATGCATAAGGACAGCAGTGGACATGTTGGCTTTATCTTT AAAAGTGGAAAAATCACATCCATAGTAAAAGATAGTTCTGCTGCCAGAAACGGCCTCCTCACTGACCACC ACATCTGTGAGATCAACGGACAGAACGTCATTGGCTTGAAGGATGCTCAGATTGCAGATATACTGTCAAC AGCTGGGACTGTGGTTACCATCACAATCATGCCTACTTTTATCTTCGAACACATTATTAAACGGATGGCT CCCAGCATTATGAAAAGCCTGATGGATCACACCATTCCTGAAGTTTAAACCCTTGTACAATGCATCACGG CTGAATGTTTCCAGTTTTCCTCTTCGGCAACTTGTCTATTTCGCACATGAAGCTTTCCCGGAGCCAGGGA GAATCTGCTGCATGGAGACCTTTCTATCTTCTCTCATAGCTGGGAACCCGCTCTATCTGATACTGGCTTC AGATTTTAAGATGGGTGTAGCCTTAGCCTGGTTTTACAGATGTGAGACTCCCAAAAGATTTACTGACTTT CCTAGACTGGGTTCTTTACTGGGAACCTGATGTTTTTATATAAGCCATTGTGATTACGATGACTGGTATA GGCTTAGCTGTGTCTGAGACCTGGTCAGCTTTCTTCTAGAACAAAGCACAGTGCTAGTCATGTGCTTCAA TTCTGTGGCATTCTTGGACTTTAGTACATCAGCATAGTACATTTAGAATGATTGCCTTTGATAGTTATTT TTTTAAGTTTTCTCTGTGTGAGTGTGTAAAATTCCAATTAATCAACACTGTTTTCATTCCACAAAAGCAT TACACAGTTGTGTGTAGGTTGCAAGAGACTGTAATGATTGTCACTAATCTTAACTACCTTCACTTAATAT GCTTCAATTGTCGCCTTAACTACAGTAAGCATTTAGAATAAAAGCCAAAATAGAATTATTGCTGCCTTCT GAAACTTGAGATGTTAGCTCTCTATTAAGCTGTTCTGTGCTAGCCCTGAGCAGCTCACTGGTAAAGCAGA GCTGCCTACTTGTATCAAGATTTTCTAGTCACTGCATAAAGGAAACGCCTAAGAGTTGCCGTATTGCTTT CTGAGAAACAAATTGCTATATATTTCATGTAAAAGTTGTTATACTAAATAGAATAAATTTTGGAGTCTCT TTTTCACTCTAGTGGGTAATATCTAATTTGGCATTTGAGTCCTAACATTATGTAACTTTAGCTAGGTTGG GGTCGTTTTAGAATGTTTCCCTAGTCATCTTAATTTGTTCCATTTTCTGACTCTGTCCTATAAACAAAAA TGGCAATGACACTTTATGATTTTTTCTTTCTTAGCTTGTGCCTATCCTATTATTTTATGTGATATTATTA AATGTATAAAAATGTGAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_016807 |
| Insert Size | 900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC019400, AAH19400 |
| RefSeq Size | 2064 bp |
| RefSeq ORF | 900 bp |
| Locus ID | 53378 |
| UniProt ID | O08992 |
| Gene Summary | Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis. Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1. In concert with SDC1/4 and PDCD6IP, regulates exosome biogenesis (By similarity). Regulates migration, growth, proliferation, and cell cycle progression in a variety of cancer types (PubMed:26539120). In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in a shorter protein (isoform 2). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG204141 | Sdcbp (tGFP-tagged) - Mouse syndecan binding protein (Sdcbp) |
CNY 2,850.00 |
|
| MG216931 | Sdcbp (tGFP-tagged) - Mouse syndecan binding protein (Sdcbp) transcript variant 2, (10ug) |
CNY 2,850.00 |
|
| MR216931 | Sdcbp (Myc-DDK-tagged) - Mouse syndecan binding protein (Sdcbp), transcript variant 2 |
CNY 2,400.00 |
|
| MR216931L3 | Lenti ORF clone of Sdcbp (Myc-DDK-tagged) - Mouse syndecan binding protein (Sdcbp), transcript variant 2 |
CNY 4,750.00 |
|
| MR216931L4 | Lenti ORF clone of Sdcbp (mGFP-tagged) - Mouse syndecan binding protein (Sdcbp), transcript variant 2 |
CNY 4,800.00 |
