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Vrk1 (NM_001029843) Mouse Untagged Clone
CAT＃: MC209644
Vrk1 (untagged) - Mouse vaccinia related kinase 1 (Vrk1), transcript variant 2, (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 51PK |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC209644 representing NM_001029843
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCCCGTGTAAAAGCAGCTCAGGCTGGAAGACCCGGACCTGCGAAGAGGCGCCTCGCAGAGCAGTTTG CCGCTGGAGAGGTCCTAACCGACATGTCTAGGAAGGAGTGGAAACTAGGATTGCCCATTGGCCAAGGTGG CTTTGGCTGCATCTATCTGGCGGACACAAATTCTTCCAAACCGGTTGGCAGTGACGCGCCCTGTGTTGTG AAAGTGGAACCCAGTGACAATGGACCTCTTTTCACGGAATTAAAGTTCTACCAGAGGGCTGCTAAACCAG AGCAAATTCAGAAATGGATTCGTACACATAAATTGAAGTACCTTGGTGTTCCTAAGTATTGGGGATCTGG TCTACATGATAAAAATGGAAAAAGTTACAGGTTTATGATAATGGACCGCTTTGGGAGTGACCTTCAGAAA ATATATGAAGCAAATGCCAAAAGGTTTTCTCGGAAAACTGTATTGCAGCTAAGCTTAAGAATTCTGGATA TCCTGGAGTACATCCATGAGCATGAGTACGTGCACGGGGACATCAAGGCCTCCAACCTGCTCCTGAGTCA CAAGAACCCTGACCAGGTATATTTGGTAGACTATGGCCTTGCTTATCGGTACTGCCCAGATGGAGTTCAT AAAGAGTACAAGGAAGATCCCAAAAGGTGCCATGACGGCACCCTGGAGTTCACCAGCATCGACGCTCACA AAGGCGTGGCCCCATCAAGACGTGGTGATTTGGAAATACTTGGTTATTGCATGATCCAGTGGCTCAGCGG CTGTCTTCCTTGGGAAGATAACTTGAAAGATCCTAACTACGTTAGGGATTCCAAAATTAGATACAGAGAC AACGTCGCAGCTTTGATGGAGAAATGCTTTCCTGAGAAAAATAAGCCAGGTGAGATCGCTAAGTACATGG AGTCTGTGAAACTACTGGAATACACCGAAAAACCTCTCTATCAAAACCTACGTGATATCCTTTTACAAGG ACTAAAAGCTATAGGAAGTAAAGACGACGGCAAACTGGATTTTAGTGCTGTGGAGAACGGAAGTGTGAAG ACAAGACCAGCCTCAAAGAAGCGGAAGAAAGAAGCAGAAGAAAGCGCGGTGTGCGCTGTGGAGGACATGG AGTGCTCAGACACACAGGTGCAAGAGGCCGCACAGACCCGTTCCAGGAGGCAGCAGCATTTGGGATTGGA ACAAGACATGCTAAGGCTAGACCGTAGGGGTTCACGAACCAGAAAGAAAGCCCAGAAGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001029843 |
| Insert Size | 1251 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001029843.1, NP_001025014.1 |
| RefSeq Size | 3724 bp |
| RefSeq ORF | 1251 bp |
| Locus ID | 22367 |
| UniProt ID | Q80X41 |
| Gene Summary | Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (b) lacks an internal segment, compared to isoform a. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG224531 | Vrk1 (tGFP-tagged) - Mouse vaccinia related kinase 1 (Vrk1) transcript variant 2, (10ug) |
CNY 4,560.00 |
|
| MR224531 | Vrk1 (Myc-DDK-tagged) - Mouse vaccinia related kinase 1 (Vrk1), transcript variant 2 |
CNY 4,180.00 |
|
| MR224531L3 | Lenti ORF clone of Vrk1 (Myc-DDK-tagged) - Mouse vaccinia related kinase 1 (Vrk1), transcript variant 2 |
CNY 6,080.00 |
|
| MR224531L4 | Lenti ORF clone of Vrk1 (mGFP-tagged) - Mouse vaccinia related kinase 1 (Vrk1), transcript variant 2 |
CNY 6,080.00 |
