Unc93b1 (NM_001161428) Mouse Untagged Clone
CAT#: MC209978
Unc93b1 (untagged) - Mouse unc-93 homolog B1 (C. elegans) (Unc93b1), transcript variant 2, (10ug)
CNY 3,990.00
Product images
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Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | Unc-93B1; Unc93b |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC209978 representing NM_001161428
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGGAAGTCCCAACCAGCTGCTGGTGCCCAGAACTGCAAGCCCTTGATCTGGATCTGGTCATGGAGG TGGAGCCTCCGCTCTACCCTGTGGCCGGGGCCGCGGGTCCTCAAGGGGATGAAGACCGGCACGGAGTTCC TGATGGGCCAGAGGCTCCCTTGGACGAACTCGTGGGTGCGTACCCCAACTACAATGAGGAGGAGGAAGAG CGCCGCTACTACCGCCGCAAGCGCCTCGGAGTGGTCAAGAACGTGCTGGCGGCCAGCACGGGTGTCACCC TTACTTACGGCGTCTACCTGGGCCTCCTGCAGATGCAACTGATCCTGCACTATGATGAGACCTACAGAGA GGTGAAGTATGGCAACATGGGGCTGCCGGACATCGATAGCAAGATGCTGATGGGTATCAACGTGACGCCT ATCGCTGCCCTGCTCTACACACCTGTGCTCATCAGGTTTTTTGGTACCAAGTGGATGATGTTCTTGGCTG TGGGCATCTATGCCCTCTTTGTCTCTACCAACTACTGGGAACGCTACTACACGCTGGTGCCCTCTGCTGT GGCTCTGGGCATGGCCATTGTGCCTCTGTGGGCCTCCATGGGCAACTATATCACCAGGATGTCCCAGAAG TACTATGAATACTCCCACTACAAGGAGCAAGATGAGCAGGGACCTCAGCAGCGCCCACCACGAGGTTCCC ACGCACCCTATCTCCTGGTTTTCCAGGCCATCTTCTATAGCTTCTTCCACTTGAGCTTCGCGTGTGCCCA GCTGCCCATGATTTACTTCCTCAACAACTACCTGTATGACCTGAACCACACACTGATCAACGTGCAGAGC TGCGGTACTAAGAGCCAAGGCATTCTGAATGGCTTCAACAAGACGGTCCTTCGGACGCTGCCGCGCAGCA AAAACCTTATTGTTGTAGAGAGCGTGCTCATGGCGGTGGCCTTCTTGGCCATGCTGATGGTGCTGGGCCT GTGTGGAGCCGCTTACCGGCCCACGGAAGAGATCGACCTGCGCAGCGTGGGCTGGGGCAACATCTTCCAG CTGCCCTTCAAACACGTGCGTGACTTTCGCTTACGCCATCTGGTGCCCTTCTTTATCTACAGTGGCTTTG AGGTGCTCTTTGCCTGCACTGGTTTTGCCCTGCACTCCTGGGCATCCTATATGAAGACAAAGAGAGGCAG GACTTCATCTTCACCATCTATCACTGGTGGCAGGCCGTGGCCATCTTTGTTGTGTACCTGGGCTCCAGCT TGCCCATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001161428 |
Insert Size | 1269 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001161428.1, NP_001154900.1 |
RefSeq Size | 2003 bp |
RefSeq ORF | 1269 bp |
Locus ID | 54445 |
UniProt ID | Q8VCW4 |
Gene Summary | Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (b) is shorter and has a distinct C-terminus, compared to isoform a. |
Documents
Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG224858 | Unc93b1 (tGFP-tagged) - Mouse unc-93 homolog B1 (C. elegans) (Unc93b1) transcript variant 2, (10ug) |
CNY 7,456.00 |
|
MR224858 | Unc93b1 (Myc-DDK-tagged) - Mouse unc-93 homolog B1 (C. elegans) (Unc93b1), transcript variant 2 |
CNY 4,180.00 |
|
MR224858L3 | Lenti ORF clone of Unc93b1 (Myc-DDK-tagged) - Mouse unc-93 homolog B1 (C. elegans) (Unc93b1), transcript variant 2 |
CNY 6,080.00 |
|
MR224858L4 | Lenti ORF clone of Unc93b1 (mGFP-tagged) - Mouse unc-93 homolog B1 (C. elegans) (Unc93b1), transcript variant 2 |
CNY 6,080.00 |
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