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Hcar2 (NM_030701) Mouse Untagged Clone
CAT＃: MC211930
Niacr1 (untagged) - Mouse niacin receptor 1 (Niacr1), (10ug)
CNY 3,656.00
CNY 3,990.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Gpr109a; Gpr109b; HM74; mHM74b; Niacr1; PUMA-G; Pumag |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC211930 representing NM_030701
Red=Cloning site Blue=ORF TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGCAAGTCAGACCATTTTCTAGTGATAAACGGCAAGAACTGCTGTGTGTTCCGAGATGAAAACATCG CCAAGGTCTTGCCACCGGTGTTGGGGCTGGAATTTGTGTTCGGACTCCTGGGCAATGGCCTTGCCTTGTG GATTTTCTGTTTCCACCTCAAGTCCTGGAAATCCAGCCGGATTTTCTTGTTCAACTTGGCCGTGGCTGAC TTTCTCCTGATCATCTGCCTGCCGTTCCTGACGGACAACTATGTCCATAACTGGGACTGGAGGTTCGGAG GCATCCCTTGCCGTGTGATGCTCTTCATGTTGGCTATGAACCGACAGGGCAGCATCATCTTCCTCACCGT GGTGGCTGTGGACCGCTACTTCCGGGTGGTCCATCCACACCACTTCTTGAACAAGATCTCCAACCGGACG GCGGCCATCATTTCTTGCTTCTTGTGGGGTCTCACCATCGGCCTGACTGTCCACCTCCTCTATACAAACA TGATGACCAAAAATGGCGAGGCATATCTGTGTAGCAGCTTCAGCATCTGTTACAACTTCAGGTGGCACGA TGCTATGTTCCTCTTGGAATTCTTCTTGCCCCTGGCCATCATCTTGTTCTGCTCAGGCAGGATCATCTGG AGCCTGAGGCAGAGACAGATGGACAGACATGCCAAGATCAAGAGGGCCATCAACTTCATCATGGTGGTGG CTATTGTATTCATCATTTGCTTCCTACCCAGTGTGGCTGTGCGCATCCGCATCTTCTGGCTTCTCTACAA ATATAACGTACGCAACTGTGACATCTACTCCTCGGTGGACCTGGCTTTCTTTACCACCCTTAGCTTTACC TACATGAACAGCATGCTGGACCCTGTGGTCTACTATTTCTCCAGCCCATCTTTCCCCAACTTCTTCTCCA CGTGTATCAACCGCTGCCTTCGAAAGAAAACATTGGGTGAACCCGATAATAACCGAAGCACTAGTGTGGA GCTCACGGGGGACCCCAGCACAACCAGAAGTATTCCAGGGGCGCTAATGGCTGACCCCAGTGAGCCAGGC AGCCCCCCTTATCTGGCTTCCACATCTCGTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_030701 |
| Insert Size | 1083 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC125296, AAI25297 |
| RefSeq Size | 1315 bp |
| RefSeq ORF | 1083 bp |
| Locus ID | 80885 |
| UniProt ID | Q9EP66 |
| Gene Summary | Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Hippuric acid and 3-(3-hydroxyphenyl) propionic acid inhibit murine osteoclastogenesis through RANKL-RANK independent pathway
,Zhao, H;Lazarenko, OP;Chen, JR;,
J. Cell. Physiol.
,PubMed ID 31271661
[HCAR2]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223099 | Niacr1 (tGFP-tagged) - Mouse niacin receptor 1 (Niacr1), (10ug) |
CNY 3,140.00 |
|
| MR223099 | Niacr1 (Myc-DDK-tagged) - Mouse niacin receptor 1 (Niacr1) |
CNY 3,656.00 |
|
| MR223099L3 | Lenti ORF clone of Niacr1 (Myc-DDK-tagged) - Mouse niacin receptor 1 (Niacr1) |
CNY 4,750.00 |
|
| MR223099L4 | Lenti ORF clone of Niacr1 (mGFP-tagged) - Mouse niacin receptor 1 (Niacr1) |
CNY 4,750.00 |
