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Hcar2 (NM_030701) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR223099L3V
- LentiORF®
-
Lenti ORF particles, Niacr1 (Myc-DDK-tagged) - Mouse niacin receptor 1 (Niacr1), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Hcar2 (NM_030701) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Gpr109a; Gpr109b; HM74; mHM74b; Niacr1; PUMA-G; Pumag |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_030701 |
| ORF Size | 1080 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR223099).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_030701.2 |
| RefSeq Size | 1938 bp |
| RefSeq ORF | 1083 bp |
| Locus ID | 80885 |
| Gene Summary | Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.[UniProtKB/Swiss-Prot Function] |
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