United States
Germany
Japan
United Kingdom
China
Pitrm1 (BC006917) Mouse Untagged Clone
CAT＃: MC218111
Pitrm1 (untagged) - Mouse pitrilysin metallepetidase 1 (cDNA clone MGC:11969 IMAGE:3601081), (10ug)
CNY 6,940.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | MP1, mKIAA1104, Ntup1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC006917
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGCCAGACGACAAGTATTATGAAAAGCAAACTCAGATGGAGACAGAAAAGCTGGAGCAAAAGGTGA ATTCTCTCTCCCCGGCGGACAAGCAGCAGATCTACGAGAAAGGTTTAGAACTACAGACGCAGCAAAGTAA ACATCAAGACGCCTCCTGCCTCCCAGCATTGAAAGTCTCGGACATTGAGCCCTCCATGCCTTTCACCAAG CTTGACATCGGCCTTGCAGCTGGAGACATCCCTGTGCAGTACTGCCCACAGCCCACCAACGGCATGGTGT ATTTCCGAGCCTTTTCCAGTTTAAACACGCTGCCGGAGGACCTGAGGCCCATTGTGCCTCTCTTTTGCAG CGTGCTGACCAAGCTGGGTTGTGGCATCCTTAACTACAGAGAGCAAGCCCAACAGATTGAGCTCAAGACA GGAGGCATGAGTGTCACGCCCCATGTGCTCCCTGACGACTCACAGCTGGATACCTACGAGCAGGGTGTGT TATTTTCATCTCTCTGCCTGGAGCGGAACCTGCCAGACATGATGCATCTGTGGAGCGAAATATTTAACAA TCCATGCTTTGAAGAAGAAGAACACTTCAAAGTGTTGGTGAAGATGACCGCTCAGGAGCTCTCCAATGGA ATTTCAGACTCGGGGCATCTCTATGCAGCCCTCAGAGCAAGCAAGACACTGACACCTTCAGGGGACTTGC AGGAGACCTTCAGTGGGATGGATCAGGTGAAGGTGATGAAAAGAATTGCAGAGATGACAGACATCAAGCC CATCCTGAGAAAACTGCCCCGGATCAAGAAGTATCTACTAAACTGTGACAACATGAGATGCTCAGTGAAT GCCACCCCTCAGCAGATGCCTCAGGCAGAAAAAGAGGTGGAAAACTTCCTTAGAAATGTTGGCCGAAGCA AAAAGGAACGGAAGCCTGTCCGCCCGCATATTGTCGAGAAACCCACACCCAGTGGCCCCAGTGGAGCTGC ACATGTCAGTGGGTCCCAGATCGTCAGAAAATTGGTGACAGACCCCACCTTCAAACCCTGCCAGATGAAG ACACATTTTGTGCTGCCCTTCCCTGTGAATTACATTGGCGAGTGTGTCAGGACTGTCCCGTATGCTGATC CAGACCATGCCAGCCTTAAGATCCTTGCCCGTCTAATGACAGCTAAATTCTTGCATACGGAAATTCGAGA GAAGGGGGGTGCTTATGGTGGCGGTGCTAAACTCACCCACAGTGGGATTTTCACGCTTTACTCTTACAGG GATCCCAATTCCATAGAAACACTCCAGTCTTTTGGGAAAGCTGTAGACTGGGCTAAGTCTGGAAAGTTCA CACAGCAGGACATTGATGAAGCCAAGCTGTCTGTTTTCTCTACTGTGGATTCTCCTGTTGCTCCATCCGA TAAAGGAATGGACCACTTCTTGTATGGCCTCTCCGATGAGATGAAGCAGGCATACCGAGAACAGCTCTTT GCTGTCAACCACGACAAACTGACCTCTGTGAGCCATAAATACCTTGGCATCGGGAAGAGCACACACGGCC TGGCTATCCTCGGACCAGAGAACTCAAAAATTGCCAAAGACCCATCATGGATCATAAAATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCTGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | BC006917 |
| Insert Size | 1602 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC006917, AAH06917 |
| RefSeq Size | 2237 bp |
| RefSeq ORF | 1601 bp |
| Locus ID | 69617 |
| Gene Summary | Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing. Has an ATP-independent activity. Specifically cleaves peptides in the range of 5 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. Degrades the transit peptides of mitochondrial proteins after their cleavage. Also degrades other unstructured peptides. It is also able to degrade amyloid-beta protein 40, one of the peptides produced by APP processing, when it accumulates in mitochondrion. It is a highly efficient protease, at least toward amyloid-beta protein 40. Cleaves that peptide at a specific position and is probably not processive, releasing digested peptides intermediates that can be further cleaved subsequently.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG208541 | Pitrm1 (tGFP-tagged) - Mouse pitrilysin metallepetidase 1 (cDNA clone MGC:11969 IMAGE:3601081) |
CNY 5,890.00 |
|
| MR208541 | Pitrm1 (Myc-DDK-tagged) - Mouse pitrilysin metallepetidase 1 (cDNA clone MGC:11969 IMAGE:3601081) |
CNY 3,968.00 |
|
| MR208541L3 | Lenti ORF clone of Pitrm1 (Myc-DDK-tagged) - Mouse pitrilysin metallepetidase 1 (cDNA clone MGC:11969 IMAGE:3601081) |
CNY 7,220.00 |
|
| MR208541L4 | Lenti ORF clone of Pitrm1 (mGFP-tagged) - Mouse pitrilysin metallepetidase 1 (cDNA clone MGC:11969 IMAGE:3601081) |
CNY 7,220.00 |
