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Sppl2b (NM_175195) Mouse Untagged Clone
CAT＃: MC219200
Sppl2b (untagged) - Mouse RIKEN cDNA 3110056O03 gene (3110056O03Rik), (10ug)
CNY 7,320.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 3110056O03Rik; AW550292; PSL1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC219200 representing NM_175195
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCGCGGCGCGGCTGGCCGCAGCTTTGCTGCTACTCGCGGCCCAGGTGGCCTGTGAGTTCGGCGTGC TTCGAGTGGTGTCCCAAACCAGTAGGACTCGGAGCAGGGACTACTGCATCCTCTACAACCCACAGTGGGC CCACTTGCCACATGACCTCAGCAAAGTGTCTCTCCTGAAGCTTCGAGACTTGAGCACCACCCAGCTCTGT TCCTACCTTGACGTCCCTGCAGAAGACTTCACCAACCAAATCGCACTGGTGGCCCGGGGCAACTGTACCT TCTATGAGAAAGTGCGGCTGGCCCAGGGCAGTGGGGCTCACGGGCTGCTGATAGTCAGCAAGGAGAAGCT GGTCCCTCCAGGAGGCAACAAGACACAGTATGAGGAGATAAGCATCCCTGTGGCCCTGCTGAGCCACAGA GACCTTCAAGACATCTTCAGGCGCTTTGGCCGTGAGGTAATGGTGGCACTGTATGCTCCGAGCGAGCCAG TGATGGACTACAACATGGTCATCATCTTTGTCATGGCCGTGGGCACCGTCGCCATCGGTGGCTACTGGGC TGGCAGCCATGATGTGAAGAAGTACATGAAGCATAAGCGAGACGATGGTCCTGAGAAACAGGAGGATGAG GCGGTGGACGTGACGCCAGTCATGATCTGCGTGTTTGTTGTAATGTGCTGCTTCATGCTTGTGCTTCTCT ACTACTTCTATGACCGCCTGGTCTACGTGATCATTGGAATCTTCTGCCTGGCCTCCTCCACCGGTCTCTA CAGCTGTCTGGCACCCTTTGTGCGGAAGCTGCCCTTCTGCACGTGCAGGGTCCCCGACAACAACCTGCCG TACTTCCACAAGCGCCCACAGGCCCGCATGCTGCTGCTGGCACTCTTCTGTGTCACTGTCTCCGTGGTGT GGGGTATCTTCCGAAATGAGGACCAGTGGGCATGGGTCCTGCAAGACACCCTGGGCATTGCCTTCTGCCT GTACATGCTGAAGACCATCCGCCTGCCTACCTTCAAGGCCTGCACGCTGCTGCTGCTGGTGCTCTTCATC TACGACATCTTCTTTGTCTTCATCACCCCCTTCCTGACCAAGAGTGGCAACAGCATCATGGTGGAGGTGG CCACCGGGCCCTCGAACTCATCCACCCATGAGAAGCTGCCCATGGTGCTGAAGGTGCCCAGGCTGAACAC CTCGCCACTCTCCCTGTGTGACCGGCCCTTCTCCCTCCTGGGCTTTGGAGACATCTTGGTGCCAGGGCTG CTGGTGGCCTACTGTCACAGGTTTGATATCCAGGTGCAGTCCTCCAGAATTTACTTTGTGGCCTGTACCA TTGCCTATGGCCTGGGCCTCCTGGTGACCTTCGTGGCTCTTGTCCTCATGCAGCGTGGCCAGCCTGCACT ACTCTACCTGGTCCCTTGCACACTGCTGACCAGCTGCACCGTGGCTCTGTGGCGCCGGGAGCTGGGTGCC TTCTGGACGGGCAGCGGTTTTGCGAAGGATGCACCTCAGACCCCGTGGGCCGCAACCCAGGGACCTGTGC CTCCGAAGGCTGTGGGTTCCTCCCTCTCCGAGCAGCCTCCAAGTGAAGAGCTAGCCAAGAGCCCCCTGTC CACTGAGGAGGCCGGAGCCGCAGACCCTGCCAAGGATCCTGACAACCCTGTGGCCAGTCCCCTCAGCCCC TCAAATGGGGATGAGGCTCAGCCTATCCCTGTGGTGAAGCCAGAGACTTCGGCCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_175195 |
| Insert Size | 1737 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_175195.3, NP_780404.2 |
| RefSeq Size | 2887 bp |
| RefSeq ORF | 1737 bp |
| Locus ID | 73218 |
| UniProt ID | Q3TD49 |
| Gene Summary | Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG220301 | Sppl2b (tGFP-tagged) - Mouse RIKEN cDNA 3110056O03 gene (3110056O03Rik), (10ug) |
CNY 5,040.00 |
|
| MR220301 | Sppl2b (Myc-DDK-tagged) - Mouse RIKEN cDNA 3110056O03 gene (3110056O03Rik) |
CNY 4,304.00 |
|
| MR220301L3 | Lenti ORF clone of Sppl2b (Myc-DDK-tagged) - Mouse RIKEN cDNA 3110056O03 gene (3110056O03Rik) |
CNY 6,460.00 |
|
| MR220301L4 | Lenti ORF clone of Sppl2b (mGFP-tagged) - Mouse RIKEN cDNA 3110056O03 gene (3110056O03Rik) |
CNY 6,460.00 |
