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Ptpn11 (NM_001109992) Mouse Untagged Clone
CAT＃: MC219394
Ptpn11 (untagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 2, (10ug)
CNY 4,424.00
CNY 7,510.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2700084A17Rik; AW536184; PTP1D; PTP2C; SAP-2; SH-PTP2; SH-PTP3; SHP-2; Shp2; Syp |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC219394 representing NM_001109992
Red=Cloning site Blue=ORF TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACATCGCGGAGATGGTTTCACCCCAACATCACTGGTGTGGAGGCAGAGAATCTCCTGCTGACCAGAG GAGTCGATGGCAGTTTTTTAGCAAGGCCCAGTAAGAGTAACCCTGGAGACTTCACTCTGTCTGTTAGAAG AAATGGAGCTGTTACCCACATCAAGATTCAGAACACTGGGGACTACTATGACCTCTATGGTGGGGAGAAG TTTGCCACTTTGGCTGAACTGGTTCAGTATTACATGGAACACCATGGGCAGCTGAAAGAGAAGAATGGAG ATGTTATCGAGCTCAAGTACCCGCTGAACTGTGCAGACCCTACCTCTGAAAGGTGGTTCCATGGTCACTT GTCTGGAAAAGAAGCAGAGAAGCTGCTGACGGAGAAGGGCAAGCATGGCAGCTTCCTCGTTCGAGAGAGC CAGAGCCACCCCGGAGACTTCGTTCTCTCCGTGCGCACTGGTGACGACAAAGGGGAGAGCAACGACGGCA AGTCCAAAGTGACCCACGTCATGATCCGCTGTCAGGAGCTGAAATACGACGTTGGTGGGGGAGAGCGCTT TGACTCTCTGACAGACCTGGTGGAGCATTACAAGAAGAACCCCATGGTGGAGACGCTGGGCACAGTCCTG CAGCTCAAGCAGCCCCTCAACACAACTCGTATCAATGCTGCTGAAATTGAAAGCCGGGTTCGAGAGTTAA GCAAGCTGGCTGAGACCACAGATAAAGTCAAGCAGGGCTTTTGGGAAGAGTTTGAGACGCTCCAGCAACA GGAATGCAAACTTCTCTATAGCCGAAAAGAAGGACAGAGACAAGAAAATAAAAACAAAAACAGATACAAA AACATCCTGCCCTTTGATCATACCAGGGTCGTTCTGCATGATGGGGATCCCAATGAGCCTGTTTCTGATT ACATTAATGCAAACATCATCATGCCTGAGTTTGAGACCAAGTGCAACAATTCCAAACCCAAAAAGAGTTA CATTGCCACTCAAGGCTGCCTGCAGAACACGGTGAATGACTTCTGGCGGATGGTGTTCCAGGAGAACTCT CGAGTCATTGTCATGACCACAAAGGAAGTGGAGAGAGGGAAGAGCAAATGTGTCAAGTACTGGCCTGATG AGTATGCGCTCAAAGAATACGGGGTCATGCGTGTTAGGAACGTCAAAGAAAGTGCCGCCCATGACTACAC TTTACGAGAGCTCAAACTCTCTAAGGTCGGACAAGGAAACACAGAGAGAACCGTCTGGCAGTACCACTTT CGGACCTGGCCAGACCATGGCGTGCCTAGTGACCCTGGAGGTGTGCTGGACTTCCTGGAGGAGGTCCACC ACAAGCAGGAGAGCATCGTGGATGCAGGCCCTGTCGTGGTTCACTGCAGCGCTGGGATTGGCCGGACAGG AACCTTCATTGTGATTGACATCCTTATTGACATCATTCGAGAGAAAGGTGTGGACTGTGACATCGACGTT CCTAAAACCATTCAGATGGTGCGGTCCCAGAGGTCGGGGATGGTCCAGACAGAAGCACAGTACCGGTTTA TCTACATGGCTGTCCAGCACTACATAGAGACGCTGCAGCGCCGGATCGAGGAGGAGCAGAAAAGCAAAAG AAAAGGACATGAATATACCAATATTAAGTATTCCTTGGTGGACCAGACAAGTGGTGATCAGAGTCCCCTG CCACCCTGCACCCCAACGCCACCCTGTGCAGAAATGAGGGAGGACAGCGCCCGAGTCTATGAGAACGTGG GCCTCATGCAGCAGCAGAGGAGTTTCAGATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001109992 |
| Insert Size | 1782 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001109992.1, NP_001103462.1 |
| RefSeq Size | 5616 bp |
| RefSeq ORF | 1782 bp |
| Locus ID | 19247 |
| UniProt ID | P35235 |
| Gene Summary | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform b, which is shorter than isoform a. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Melanoma exosomes deliver a complex biological payload that upregulates PTPN11 to suppress T lymphocyte function
,null,
Pigment cell & melanoma research
,PubMed ID 27930879
[Ptpn11]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG225515 | Ptpn11 (tGFP-tagged) - Mouse protein tyrosine phosphatase non-receptor type 11 (Ptpn11) transcript variant 2, (10ug) |
CNY 6,460.00 |
|
| MR225515 | Ptpn11 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 2 |
CNY 5,890.00 |
|
| MR225515L3 | Lenti ORF clone of Ptpn11 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 2 |
CNY 7,790.00 |
|
| MR225515L4 | Lenti ORF clone of Ptpn11 (mGFP-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 2 |
CNY 7,790.00 |
