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Ptpn11 (NM_001109992) Mouse Tagged ORF Clone
CAT＃: MR225515
- TrueORF®
Ptpn11 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 2
ORF Plasmid: tGFP
"NM_001109992" in other vectors (4)
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CNY 5,890.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 2700084A17Rik; AW536184; PTP1D; PTP2C; SAP-2; SH-PTP2; SH-PTP3; SHP-2; Shp2; Syp |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR225515 representing NM_001109992
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACATCGCGGAGATGGTTTCACCCCAACATCACTGGTGTGGAGGCAGAGAATCTCCTGCTGACCAGAG GAGTCGATGGCAGTTTTTTAGCAAGGCCCAGTAAGAGTAACCCTGGAGACTTCACTCTGTCTGTTAGAAG AAATGGAGCTGTTACCCACATCAAGATTCAGAACACTGGGGACTACTATGACCTCTATGGTGGGGAGAAG TTTGCCACTTTGGCTGAACTGGTTCAGTATTACATGGAACACCATGGGCAGCTGAAAGAGAAGAATGGAG ATGTTATCGAGCTCAAGTACCCGCTGAACTGTGCAGACCCTACCTCTGAAAGGTGGTTCCATGGTCACTT GTCTGGAAAAGAAGCAGAGAAGCTGCTGACGGAGAAGGGCAAGCATGGCAGCTTCCTCGTTCGAGAGAGC CAGAGCCACCCCGGAGACTTCGTTCTCTCCGTGCGCACTGGTGACGACAAAGGGGAGAGCAACGACGGCA AGTCCAAAGTGACCCACGTCATGATCCGCTGTCAGGAGCTGAAATACGACGTTGGTGGGGGAGAGCGCTT TGACTCTCTGACAGACCTGGTGGAGCATTACAAGAAGAACCCCATGGTGGAGACGCTGGGCACAGTCCTG CAGCTCAAGCAGCCCCTCAACACAACTCGTATCAATGCTGCTGAAATTGAAAGCCGGGTTCGAGAGTTAA GCAAGCTGGCTGAGACCACAGATAAAGTCAAGCAGGGCTTTTGGGAAGAGTTTGAGACGCTCCAGCAACA GGAATGCAAACTTCTCTATAGCCGAAAAGAAGGACAGAGACAAGAAAATAAAAACAAAAACAGATACAAA AACATCCTGCCCTTTGATCATACCAGGGTCGTTCTGCATGATGGGGATCCCAATGAGCCTGTTTCTGATT ACATTAATGCAAACATCATCATGCCTGAGTTTGAGACCAAGTGCAACAATTCCAAACCCAAAAAGAGTTA CATTGCCACTCAAGGCTGCCTGCAGAACACGGTGAATGACTTCTGGCGGATGGTGTTCCAGGAGAACTCT CGAGTCATTGTCATGACCACAAAGGAAGTGGAGAGAGGGAAGAGCAAATGTGTCAAGTACTGGCCTGATG AGTATGCGCTCAAAGAATACGGGGTCATGCGTGTTAGGAACGTCAAAGAAAGTGCCGCCCATGACTACAC TTTACGAGAGCTCAAACTCTCTAAGGTCGGACAAGGAAACACAGAGAGAACCGTCTGGCAGTACCACTTT CGGACCTGGCCAGACCATGGCGTGCCTAGTGACCCTGGAGGTGTGCTGGACTTCCTGGAGGAGGTCCACC ACAAGCAGGAGAGCATCGTGGATGCAGGCCCTGTCGTGGTTCACTGCAGCGCTGGGATTGGCCGGACAGG AACCTTCATTGTGATTGACATCCTTATTGACATCATTCGAGAGAAAGGTGTGGACTGTGACATCGACGTT CCTAAAACCATTCAGATGGTGCGGTCCCAGAGGTCGGGGATGGTCCAGACAGAAGCACAGTACCGGTTTA TCTACATGGCTGTCCAGCACTACATAGAGACGCTGCAGCGCCGGATCGAGGAGGAGCAGAAAAGCAAAAG AAAAGGACATGAATATACCAATATTAAGTATTCCTTGGTGGACCAGACAAGTGGTGATCAGAGTCCCCTG CCACCCTGCACCCCAACGCCACCCTGTGCAGAAATGAGGGAGGACAGCGCCCGAGTCTATGAGAACGTGG GCCTCATGCAGCAGCAGAGGAGTTTCAGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR225515 representing NM_001109992
Red=Cloning site Green=Tags(s) MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEK FATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRES QSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVL QLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYK NILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENS RVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF RTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDV PKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPL PPCTPTPPCAEMREDSARVYENVGLMQQQRSFR TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001109992 |
| ORF Size | 1779 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001109992.1, NP_001103462.1 |
| RefSeq Size | 5616 bp |
| RefSeq ORF | 1782 bp |
| Locus ID | 19247 |
| UniProt ID | P35235 |
| MW | 68.5 kDa |
| Gene Summary | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC219394 | Ptpn11 (untagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 2, (10ug) |
CNY 4,424.00 |
|
| MG225515 | Ptpn11 (tGFP-tagged) - Mouse protein tyrosine phosphatase non-receptor type 11 (Ptpn11) transcript variant 2, (10ug) |
CNY 6,460.00 |
|
| MR225515L3 | Lenti ORF clone of Ptpn11 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 2 |
CNY 7,790.00 |
|
| MR225515L4 | Lenti ORF clone of Ptpn11 (mGFP-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 2 |
CNY 7,790.00 |
