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Scin (NM_009132) Mouse Untagged Clone
CAT＃: MC219710
Scin (untagged) - Mouse scinderin (Scin), transcript variant 2, (10ug)
CNY 7,890.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | adseverin; AW545522 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC219710 representing NM_009132
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGCAGGAGCTGCAGCACCCCGAGTTCGCGCGCGCAGGCCAGCAGGCTGGGCTGCAGGTGTGGAGGG TCGAGAAGCTGGAACTGGTACCGGTGCCCCAGGGTGCCTATGGTGACTTTTACGTCGGAGACGCCTACCT GGTGCTGCACACCACCAAGTCCAGCAGGGGCTTCTCCTACCGCCTGCATTTCTGGCTGGGAAAGGAGTGT TCCCAGGATGAGAGCACAGCGGCTGCCATCTTTACGGTCCAGATGGACGACTATTTGGGTGGCAAGCCAG TCCAGAGCAGAGAGCTTCAAGGCTATGAGTCGACTGATTTTGTGGGCTATTTCAAAGGCGGTCTGAAGTA CAAGGCTGGAGGTGTGGCTTCTGGACTAAACCATGTCCTCACCAATGATCTGACTGCGAAAAGACTTCTG CACGTGAAGGGTCGGAGAGTGGTCAGAGCCACTGAAGTTCCCCTCAGCTGGGAGAGCTTCAACAAGGGCG ACTGCTTCATCATTGACCTTGGCACCGAAATTTACCAGTGGTGTGGTTCCTCCTGCAACAAATATGAGCG TCTGAAAGCAAGCCAGGTGGCCATTGGCATCCGGGACAATGAGAGGAAAGGAAGATCTCAACTCATTGTG GTGGAAGAAGGAAGTGAACCATCAGAGCTCATGAAGGTTTTAGGGAGAAAGCCTGAGCTTCCAGATGGGG ACAATGATGACGATGTCGTAGCAGACATAAGTAACAGGAAGATGGCGAAGCTCTACATGGTTTCAGATGC AAGTGGGTCCATGAAAGTAACACTGGTGGCTGAAGAAAACCCGTTCTCCATGGGAATGTTGCTTTCTGAA GAATGCTTCATTTTGGACCATGGTGCTGCAAAACAAATTTTTGTATGGAAAGGTAAAAATGCTAACCCAC AGGAGAGGAAGACTGCCATGAAGACAGCTGAGGAGTTTTTACAGAAAATGAAGTATTCTACTAATACTCA AATTCAGGTTCTTCCGGAAGGCGGTGAAACACCAATTTTCAAACAGTTCTTTAAGGACTGGAAGGATAAA GACCAGAGTGATGGCTTTGGGAAGGTGTACATCACGGAGAAAGTGGCTCAGATAAAGCAGATTCCGTTTG ATGCCTCAAAACTGCACAGTTCTCCGCAGATGGCAGCCCAGCACAACATGGTGGACGATGGCTCTGGCGG GGTGGAGATCTGGCGTGTAGAGAACAGTGGTAGAGTCCAGATTGACCCAAGCTCCTATGGCGAGTTCTAT GGCGGTGACTGCTACATTATCCTCTACACTTATCCCAGAGGACAGATCATCTACACATGGCAAGGAGCAA ATGCTACCAGAGATGAACTGACCATGTCCGCGTTTCTGACTGTCCAGTTGGACCGGTCCCTTGGAGGGCA GGCTGTGCAGGTCCGTGTCTCTCAAGGCAAAGAGCCTGCTCACCTGCTGAGTTTGTTCAAAGACAAACCA CTCATTATTTATAAGAATGGGACATCCAAGAAAGAAGGGCAGGCACCGGCTCCCCCTACACGCCTTTTTC AAGTCCGGAGGAACCTGGCATCTATCACCAGAATTGTGGAGATTGAAGAAGTTCCGGGAGAGTTCACCCA GGATGACCTGGCAGAAGATGATGTCATGCTACTTGATGCGTGGGAACAGATCTTTATTTGGATTGGCAAA GATGCCAATGAAGTTGAGAAAAAGGAATCAGTGAAGTCTGCCAAAATGTACCTGGAGACAGACCCTTCTG GAAGAGACAAGAGGACACCGATTGTCATCATCAAGCAAGGGCACGAGCCCCCCACATTCACAGGCTGGTT TCTGGGCTGGGACTCCAGCAGGTGGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_009132 |
| Insert Size | 1848 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_009132.2, NP_033158.2 |
| RefSeq Size | 2708 bp |
| RefSeq ORF | 1848 bp |
| Locus ID | 20259 |
| UniProt ID | Q60604 |
| Gene Summary | Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane (PubMed:9671468). Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2) (By similarity). In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+) (PubMed:9671468). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles (By similarity). Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts (PubMed:25275604, PubMed:25681458). Regulates chondrocyte proliferation and differentiation (By similarity). Inhibits cell proliferation and tumorigenesis. Signaling is mediated by MAPK, p38 and JNK pathways (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks two exons in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG218765 | Scin (tGFP-tagged) - Mouse scinderin (Scin) transcript variant 2, (10ug) |
CNY 5,040.00 |
|
| MR218765 | Scin (Myc-DDK-tagged) - Mouse scinderin (Scin), transcript variant 2 |
CNY 4,560.00 |
|
| MR218765L3 | Lenti ORF clone of Scin (Myc-DDK-tagged) - Mouse scinderin (Scin), transcript variant 2 |
CNY 6,460.00 |
|
| MR218765L4 | Lenti ORF clone of Scin (mGFP-tagged) - Mouse scinderin (Scin), transcript variant 2 |
CNY 6,460.00 |
