Bmx (NM_009759) Mouse Untagged Clone
CAT#: MC220149
Bmx (untagged) - Mouse BMX non-receptor tyrosine kinase (Bmx), (10ug)
CNY 8,460.00
Product images
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Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | Etk; Etk/Bmx; Tyro8 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC220149 representing NM_009759
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACGACAATATGGAGAGTAAATCCATTCTGGAAGAACTGCTTCTCAAAAAGTCACAGCAAAAGAAGA AAATGTCACCAAATAATTACAAGGAGCGGCTTTTTGTTCTAACCAAAACAAGCCTTTCCTACTATGAATA CGACAAAATGAAAAGAGGAAGCAGAAAAGGATCAATAGAAATTAAGAAAATCAGATGTGTGGAAAAAGTC AACCTTGAGGAGCAGACACCGGTGGAGAGACAGTACCCATTTCAGATTGTGTATAAAGATGGGCTTCTTT ATGTCTATGCATCGAATGAAGAGAGCCGATGTCAGTGGTTAAAAGCGCTGCAAAAAGAGATACGGGGCAA CCCTCACCTGTTGATCAAGTATCACAGTGGCTTCTTTGTGGATGGAAAGTTCCTGTGTTGCCAGCAGAGC TGCAAAGCAGCCCCAGGATGCACTCTCTGGGAAGCATATGCTGATCTGCACATCGCAATCAGTGATGAGA AACACAGAGCTCCCACTTTCCCAGAGAGGCTACTGAAGATTCCAAGGGCAGTTCCCGTTCTCAAAATGGA TGCATCATCTTCAGGTGCCATTCTACCCCAATATGACAGCTATTCAAAGAAAAGTTGTGGTTCCCAGCCA ACCAGCAACATACGCTATATTCCAAGGGAAGACTGCCCTGACTGGTGGCAAGTAAGAAAACTGAAAAGCG AGGAAGACATTGCATGCAGTAACCAACTGGAAAGAAATATCGCCTCTCACAGCACCTCAAAGATGTCATG GGGATTCCCTGAGTCAAGTTCATCAGAAGAAGAGGAAAATCTGCATGCTTATGACTGGTTTGCTGGGAAT ATCTCCAGGTCACAATCTGAGCAGTTACTGAGACAAAAGGGAAAAGAAGGAGCATTTATGGTTCGGAATT CCAGCCAGATGGGAATGTACACTGTGTCCTTATTTAGTAAGGCTGTAAATGATAAAAAAGGAACTGTCAA GCATTACCACGTGCATACTAATGCTGAAAATAAATTATACCTGGCTGAAAACTACTGCTTTGATTCCATT CCAAAGCTCATTCACTATCACCAACATAATTCAGCAGGCATGATCACACGGCTCCGCCACCCAGTGTCAA CCAAGGCCAACAAGGTCCCGGTGTCTGTGGCTCTGGGAAGTGGAATTTGGGAACTGAAAAGAGAAGAGAT TACCTTGCTGAAGGAGCTGGGCAATGGCCAGTTTGGAGTGGTCCAGCTGGGCCAGTGGAAGGGGCAATAT GATGTGGCTGTAAAGATGATCAAGGAGGGTGCCATGTCAGAAGATGAATTCTTTCAGGAGGCCCAGACCA TGATGAAACTCAGCCATCCCAAGCTGGTGAAGTTCTACGGAGTATGCTCAAAGAAATACCCCATCTATAT AGTAACTGAGTATATAACAAATGGTTGCTTGCTTAATTACCTGAAGAGTCATGGGAAAGGACTAGAAAGT TGCCAGCTCTTAGAAATGTGTTATGATGTCTGTGAAGGCATGGCCTTCTTGGAGAGCCATCAGTTCATAC ATCGAGATTTGGCTGCTCGGAACTGTTTGGTGGACAGTGATCTCTCTGTGAAAGTCTCAGACTTTGGAAT GACGAGATATGTCCTTGATGATCAGTATGTCAGCTCAGTAGGAACCAAGTTTCCAGTCAAGTGGTCAGCT CCAGAGGTGTTTCACTACTTCAAATACAGCAGCAAGTCGGATGTATGGGCATTTGGGATCCTGATGTGGG AGGTGTTTAGTCTAGGGAAGCAGCCCTATGACTTATATGATAACTCCGAGGTGGTTGTGAAGGTCTCCCA GGGCCACAGACTCTACCGGCCCCAACTGGCATCAGACACCATCTACCAGATCATGTACAGCTGCTGGCAT GAGCTTCCAGAAAAGCGCCCCACATTTCAGCAACTCCTGTCTGCCATAGAACCACTTCGGGAACAAGATA AACCATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_009759 |
Insert Size | 1968 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_009759.4, NP_033889.2 |
RefSeq Size | 3005 bp |
RefSeq ORF | 1968 bp |
Locus ID | 12169 |
UniProt ID | P97504 |
Gene Summary | Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility. Plays a critical role in TNF-induced angiogenesis, and implicated in the signaling of TEK and FLT1 receptors, 2 important receptor families essential for angiogenesis. Required for the phosphorylation and activation of STAT3, a transcription factor involved in cell differentiation. Also involved in interleukin-6 (IL6) induced differentiation. Plays also a role in programming adaptive cytoprotection against extracellular stress in different cell systems, salivary epithelial cells, brain endothelial cells, and dermal fibroblasts. May be involved in regulation of endocytosis through its interaction with an endosomal protein RUFY1. May also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells.[UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG226349 | Bmx (tGFP-tagged) - Mouse BMX non-receptor tyrosine kinase (Bmx), (10ug) |
CNY 6,456.00 |
|
MR226349 | Bmx (Myc-DDK-tagged) - Mouse BMX non-receptor tyrosine kinase (Bmx) |
CNY 4,856.00 |
|
MR226349L3 | Lenti ORF clone of Bmx (Myc-DDK-tagged) - Mouse BMX non-receptor tyrosine kinase (Bmx) |
CNY 6,460.00 |
|
MR226349L4 | Lenti ORF clone of Bmx (mGFP-tagged) - Mouse BMX non-receptor tyrosine kinase (Bmx) |
CNY 6,460.00 |