Slc8a3 (NM_001167920) Mouse Untagged Clone

CAT#: MC220884

Slc8a3 (untagged) - Mouse solute carrier family 8 (sodium/calcium exchanger), member 3 (Slc8a3), transcript variant 1, (10ug)



  "NM_001167920" in other vectors (3)

CNY 9,120.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms AW742262; Ncx3
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC220884 representing NM_001167920
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCGTGGTTACGGCTGCAGCCTCTCACCTCTGCCTTCCTCCATTTTGGGCTGGTTACTTTTGTGCTCT
TCCTGAATTGTCTTCGAGCAGAGGCTGGTGACTCGGGGGATGTGCCCAGTGCAGGGCAGAACAATGAGTC
CTGTTCGGGGTCATCAGACTGCAAGGAGGGTGTCATTTTGCCAATCTGGTATCCAGAGAACCCTTCCCTT
GGGGACAAGATTGCCAGGGTCATTGTCTATTTTGTGGCCCTGATATACATGTTTCTTGGGGTGTCTATCA
TTGCTGACCGATTCATGGCATCTATTGAAGTCATTACTTCCCAAGAGAGGGAAGTGACCATCAAGAAGCC
CAATGGAGAGACCAGCACAACTACAATTCGGGTATGGAATGAAACTGTCTCCAATCTGACCCTGATGGCC
CTGGGCTCTTCTGCTCCAGAGATTCTCCTGTCTTTAATTGAGGTGTGTGGTCACGGGTTCATTGCTGGTG
ATCTGGGACCATCTACCATCGTTGGCAGTGCAGCCTTCAACATGTTCATCATCATTGGCATCTGTGTCTA
TGTGATCCCAGATGGGGAGACTCGAAAGATCAAGCACCTGCGAGTCTTCTTCGTCACGGCTGCTTGGAGC
ATCTTCGCCTACATTTGGCTCTATATGATCCTGGCAGTCTTCTCTCCTGGTGTGGTCCAGGTTTGGGAAG
GCCTCCTTACTCTCTTCTTCTTTCCCGTGTGTGTCCTGCTGGCTTGGGTGGCAGATAAGCGACTGCTCTT
CTACAAATACATGCACAAAAAATACCGCACAGATAAACACCGAGGAATTATCATTGAGACAGAGGGTGAC
CACCCTAAGGGCATTGAGATGGATGGGAAAATGATGAATTCTCACTTTCTAGATGGGAACTTTACACCTT
TGGAAGGAAAGGAGGTAGATGAATCTCGCAGGGAAATGATCCGGATTCTAAAGGATCTGAAACAAAAACA
CCCAGAAAAGGACCTAGATCAGCTGGTGGAGATGGCCAATTACTATGCTCTTTCCCATCAACAGAAGAGC
CGTGCTTTCTACCGCATCCAAGCCACCCGGATGATGACTGGTGCGGGCAATATACTTAAGAAGCATGCAG
CCGAGCAAGCCAAGAAGACCTCCAGCATGAGCGAGGTGCATACCGATGAGCCGGAGGACTTTGCCTCTAA
GGTCTTCTTTGACCCATGTTCTTATCAGTGCCTGGAGAACTGTGGAGCTGTCCTCCTGACCGTGGTGAGG
AAAGGGGGAGATATATCCAAGACCATGTACGTGGACTACAAAACAGAGGACGGCTCCGCCAATGCAGGGG
CAGACTATGAGTTCACAGAGGGCACTGTGGTTCTGAAGCCAGGAGAGACCCAGAAGGAGTTCTCTGTGGG
CATCATTGATGATGACATTTTTGAGGAGGATGAACACTTCTTTGTGAGGCTGAGCAATGTCCGTGTAGAA
GAGGAGCAGCTGGCGGAGGGGATGCTCCCAGCAATACTCAATAGTCTTCCTTTGCCTCGGGCTGTCCTGG
CCTCCCCTTGTGTGGCCACAGTAACCATCTTGGATGATGACCATGCAGGAATTTTCACTTTTGAATGTGA
TACCATTCATGTCAGTGAAAGTATTGGTGTTATGGAAGTCAAGGTTTTGAGGACATCAGGTGCCAGGGGC
ACAGTCATCGTCCCTTTTAGGACAGTAGAAGGGACAGCCAAGGGTGGTGGCGAGGACTTTGAAGATGCAT
ATGGGGAGCTGGAGTTCAAGAATGATGAAACAGTGAAAACCATAAGGGTTAAAATAGTAGATGAGGAGGA
GTACGAGAGGCAAGAGAATTTCTTCATTGCCCTTGGTGAACCGAAATGGATGGAACGTGGAATATCAGAA
GTGACAGACAGGAAGCTGACTGTGGAGGAAGAGGAAGCCAAGAGAATAGCAGAGATGGGAAAGCCAGTAT
TGGGTGAACACCCCAAACTAGAGGTCATCATTGAAGAGTCCTATGAGTTCAAGAGTACAGTGGATAAGCT
GATCAAGAAGACAAACCTGGCATTGGTTGTGGGGACCCATTCCTGGAGGGACCAGTTCATGGAAGCCATC
ACTGTTAGTGCAGGAGGGGATGAGGATGAAGACGAATCTGGAGAGGAGAGGCTGCCATCCTGCTTTGACT
ACGTCATGCACTTCCTGACGGTCTTCTGGAAGGTGCTCTTTGCCTGTGTGCCCCCCACAGAGTACTGCCA
CGGCTGGGCCTGCTTCGTGGTCTCCATCCTCATTATTGGCATGCTCACCGCCATCATCGGGGACCTGGCC
TCTCACTTCGGCTGCACCATCGGGCTCAAGGATTCGGTCACAGCTGTTGTTTTTGTGGCATTCGGCACCT
CTGTGCCAGATACATTTGCCAGCAAAGCCGCTGCCCTGCAGGACGTGTATGCAGATGCTTCCATTGGCAA
CGTCACAGGCAGTAATGCCGTCAATGTCTTCCTGGGTATTGGTTTGGCCTGGTCCGTGGCCGCCATCTAC
TGGGCCATGCAGGGACAGGAGTTCCATGTGTCCGCTGGCACTCTGGCCTTCTCGGTCACTCTTTTCACCA
TCTTTGCATTTGTCTGCCTCAGTGTGCTCTTGTATCGTCGGCGGCCCCATCTGGGCGGGGAGCTCGGAGG
TCCTCGTGGCTGCAAGCTTGCCACGACATGGCTCTTTGTGAGCCTATGGCTCCTCTACATACTATTTGCC
ACGCTGGAGGCCTACTGCTACATCAAGGGGTTCTGA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001167920
Insert Size 2766 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001167920.1, NP_001161392.1
RefSeq Size 4943 bp
RefSeq ORF 2766 bp
Locus ID 110893
UniProt ID S4R2P9
Gene Summary Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells, both in muscle and in brain (PubMed:14722618, PubMed:21593315). In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A3 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline (PubMed:14722618, PubMed:21593315). Contributes to Ca(2+) transport during excitation-contraction coupling in muscle (PubMed:14722618). In neurons, contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory (PubMed:21593315). Required for normal oligodendrocyte differentiation and for normal myelination (PubMed:21959935). Mediates Ca(2+) efflux from mitochondria and contributes to mitochondrial Ca(2+) ion homeostasis (PubMed:24616101). Isoform 1 displays higher calcium exchanger activity than isoform 2, probably because isoform 1 has a lower threshold for activation by cytoplasmic Ca(2+) (PubMed:24616101).[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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