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Afg3l2 (NM_027130) Mouse Untagged Clone
CAT＃: MC221711
Afg3l2 (untagged) - Mouse AFG3(ATPase family gene 3)-like 2 (yeast) (Afg3l2), (10ug)
CNY 10,260.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2310036I02Rik; AW260507; Emv66; par |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221711 representing NM_027130
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCCACCGCTGCCTGCTGCTGTGGAGCCGGGGCGGCTGCCGTCGCGGCCTTCCTCCCCTGCTCGTGC CCAGAGGTTGCCTGGGTCCGGACCGGCGGCCCTGCCTCCGTACGCTCTATCAATATGCTACTGTCCAGAC AGCAAGCAGCAGGCGTTCTCTGCTGAGGGATGTAATTGCTGCTTATCAAAGATTCTGTTCTCGACCTCCC AAAGGATTTGAAAAGTACTTTCCTAATGGGAAAAACGGAAAAAAGGCCAGTGAGCCTAAGGAGGCTGTTG GAGAAAAAAAAGAACCACAGCCCTCGGGCCCCCAGCCTTCTGGAGGTGCAGGTGGTGGGGGAGGGAAGCG CCGTGGCAAGAAAGAAGATTCTCACTGGTGGTCCAGGTTCCAGAAGGGTGACTTCCCATGGGATGACAAG GATTTCAGGATGTACTTTCTCTGGACTGCTCTTTTTTGGGGTGGAGTCATGATTTACTTCGTGTTCAAGA GCTCTGGGAGAGAAATCACGTGGAAAGACTTTGTCAATAACTATCTTTCTAAGGGCGTGGTGGACAGACT AGAAGTTGTCAACAAGCGTTTTGTTCGTGTGACCTTTACACCAGGAAAAACTCCGGTTGATGGGCAATAC GTCTGGTTTAATATTGGCAGTGTTGACACATTTGAGCGGAATCTGGAGACTTTGCAGCAAGAATTGGGCA TAGAAGGGGAGAACCGGGTCCCTGTGGTTTATATTGCTGAGAGCGATGGCTCCTTCCTGCTGAGCATGTT GCCCACCGTACTCATTATCGCTTTTCTACTCTACACCATAAGAAGAGGGCCCGCTGGCATTGGTCGGACC GGCCGGGGAATGGGTGGACTCTTCAGCGTTGGGGAAACCACAGCCAAGGTCTTAAAGGATGAGATAGATG TGAAGTTTAAAGATGTGGCTGGCTGTGAGGAGGCCAAGCTAGAAATAATGGAATTCGTGAATTTCTTGAA AAACCCAAAGCAATATCAAGACCTAGGAGCAAAAATCCCAAAGGGTGCCATTCTCACCGGTCCCCCAGGT ACTGGGAAGACGCTGCTAGCTAAGGCCACAGCTGGAGAAGCCAATGTCCCCTTTATCACTGTGAGCGGAT CTGAGTTTCTGGAGATGTTTGTTGGCGTTGGTCCAGCCAGAGTCCGAGACTTATTTGCCCTTGCTCGGAA GAATGCGCCTTGCATTCTCTTCATTGATGAGATTGATGCTGTGGGAAGGAAGCGCGGCAGAGGCAACTTC GGTGGGCAGAGCGAGCAGGAGAACACACTCAACCAGCTGCTTGTGGAGATGGACGGCTTCAACACAACCA CCAATGTGGTCATCCTGGCAGGCACAAATCGACCAGACATCCTGGATCCAGCTCTGTTGAGACCAGGCCG CTTTGACAGGCAGATTTTTATTGGACCCCCAGACATAAAAGGACGAGCCTCAATCTTCAAAGTTCACCTT CGACCATTGAAGCTGGACAGTGCCTTGGAAAAAGATAAATTGGCCAGAAAACTGGCGTCCTTAACTCCAG GGTTTTCAGGCGCTGATGTTGCCAATGTCTGCAATGAAGCTGCTTTGATTGCTGCAAGACACCTTTCAGA TGCCATTAATGAGAAGCACTTCGAACAAGCGATTGAGCGAGTGATTGGAGGCTTGGAGAAAAAAACCCAA GTTCTGCAGCCTGAGGAGAAGAAGACGGTGGCTTACCACGAAGCAGGCCATGCGGTCGCTGGCTGGTATC TGGAGCATGCAGACCCACTCTTAAAGGTCTCCATCATCCCGCGTGGCAAGGGGCTGGGCTATGCTCAGTA CTTGCCCAAGGAGCAGTATCTGTACACAAAGGAGCAGCTGCTGGACAGGATGTGCATGACTCTGGGCGGC CGTGTCTCCGAGGAGATCTTCTTTGGGAGAATTACAACCGGTGCCCAGGACGACTTGAGGAAGGTTACCC AGAGTGCCTATGCCCAGATCGTTCAGTTTGGCATGAACGAGAAAGTGGGGCAGATCTCCTTTGACCTCCC ACGACAGGGGGACATGGTGTTAGAGAAGCCTTACAGTGAGGCCACTGCGAGGATGATAGACGATGAAGTG AGGATACTCATCAGCGATGCCTACAGAAGGACGGTGGCTCTTCTCACAGAGAAGAAGGCTGACGTGGAGA AGGTCGCTCTCTTACTGTTAGAAAAGGAAGTCCTAGACAAGAATGACATGGTCCAGCTTCTCGGTCCCAG ACCATTTACAGAAAAGTCCACATATGAAGAATTTGTGGAAGGCACTGGCAGCTTAGACGAGGACACTTCT CTTCCTGAAGGCCTTCAGGATTGGAACAAGGAGCGGGAGAAGGAGGAGAAGAAGGAGAAGGAGAAGGAGG AGCCGCTGAATGAGAAGGTTGTCAGCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_027130 |
| Insert Size | 2409 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_027130.1, NP_081406.1 |
| RefSeq Size | 3086 bp |
| RefSeq ORF | 2409 bp |
| Locus ID | 69597 |
| UniProt ID | Q8JZQ2 |
| Gene Summary | ATP-dependent protease which is essential for axonal and neuron development (PubMed:18337413, PubMed:27642048). In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (By similarity). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210733 | Afg3l2 (tGFP-tagged) - Mouse AFG3(ATPase family gene 3)-like 2 (yeast) (Afg3l2) |
CNY 7,700.00 |
|
| MR210733 | Afg3l2 (Myc-DDK-tagged) - Mouse AFG3(ATPase family gene 3)-like 2 (yeast) (Afg3l2) |
CNY 5,888.00 |
|
| MR210733L3 | Lenti ORF clone of Afg3l2 (Myc-DDK-tagged) - Mouse AFG3(ATPase family gene 3)-like 2 (yeast) (Afg3l2) |
CNY 8,930.00 |
|
| MR210733L4 | Lenti ORF clone of Afg3l2 (mGFP-tagged) - Mouse AFG3(ATPase family gene 3)-like 2 (yeast) (Afg3l2) |
CNY 8,930.00 |
