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Intu (NM_175515) Mouse Untagged Clone
CAT＃: MC222766
Intu (untagged) - Mouse inturned planar cell polarity effector homolog (Drosophila) (Intu), (10ug)
CNY 12,070.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 9230116I04Rik; 9430087H23Rik; mKIAA1284; Pdzd6; Pdzk6 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222766 representing NM_175515
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGGCCTTGCGAGGGGAGACTCGCGTGGGCGCCCGCCCGAGCTCCCTGGAGACCTGTCCTCACAGG AAGAGGAAGAGGAGGAAGGCGACTCCGACGCCGGGGCCAGCAGCTTGGGCTCCTACTCCTCAGCCAGCAG TGACACTGATGTGGAGCCTGAGTGGCTGGACAGTGTGCAGAAGAACGGAGAACTGTTCTACCTGGAGCTG AGTGAGGACGAGGAGGAGAGCCTCCTTCCGGAGACCCAGACAGCGAACCACGTGAACCACGTGAGGTTCA GCGACAAGGAGGTCATCATCGAAGAGGACGATTCCAGAGAGAGGAAGAAGTCCGAGCCCAAGCTCAGGCG CTTCACCAAGATCTTGAAAAGCAAAAGCCTTTTACCCAGGCGTCACCACAAAAAGAGCAGCAGCAACAAT GGGCCCGTGTCCATTCTGAAACATCAGTCCTCCCAGAAGACGGGAGTCACCGTGCAGCAGCGGTACAAGG ATGTGACCGTCTACATCAACCCCAGAAAGCTGACGGCCATCAAGGCCAGGGAGCAGGTCAAACTCCTGGA AGTACTGGTGGGGATCATCCATCAGACCAAGAGGAGCTGGAAAAGGAGCGCGAAGCAGGCAGACGGAGAG AGGCTCGTGGTGCATGGCCTGTTGCCAGGAGGCTCGGCTATGAAGAGCGGTCAGGTCCTGGTTGGCGATG TCCTTGTTGCTGTGAATGATGTAGATGTGACTTCTGAAAACATAGAAAGAGTTCTGTCCTGCATCCCTGG GCCAATGCAGGTGAAGCTGACATTTGAAAACGCATATGCTGTGAAACGGGAAACAGCTCAACCCCAAAAG AAAAAGGCACAGTCGAGCACCCAAGATTTGGTGAAACTCCTCTGCGGGTCAGAGGCTGATGCTGTCCAGC ACAGTACCCTGAGCATCCCACACATCTCCATGTACCTCACACTGCAGCTCCAGTCAGAGGCAGCCAGGGA GGAGCAGGAAATTCTTTACCATTATCCAGTGTCTGAAGCATCTCAGAAACTCAAGAGCGTGAGGGGGATT TTTCTCACGCTCTGTGACATGCTGGAAAGCGTAACGGGGACACAAGTCACTAGCTCATCCCTCCATCTAA ATGGGAAACAAATTCATGTTGCTTACTTGAAAGAGTCTGACAAGTTGCTGTTAATTGGCCTGCCTGCTGA AGAAGTTCCTCTTCCTCAGTTAAGGAACATGATAGAAGATGTGGCCCAAACCCTAAAGTTCATGTATGGT TCTTTAGACAGCGCCTTCTGCCAGGTTGAGAACGCACCTCGTCTGGATCATTTCTTCAGTTTGTTCTTCG AACGAGCTCTTCGGCCCGGCAAGTTGCATCTCAGCGGCAGCCCCAGCGCCCAGCAGTATGCCGCAGCCAG TGCCGTGCTTTTGGACAATCTCCCGGGAGTCCGTTGGCTCGTGCTTCCACAGGAACTCAAGGTGGAACTG GACACAGCACTGAGTGACCTTGAGGCCGCTGACTTCGAAGAACTGTCTGAGGATTATTATGACATGAGAC GGCTGTATACAATTTTGGGTTCTTCTCTGTTTTACAAGGGTTACATGGTGTGCAGCCATCTGCCTAAGGA TGATGTTATTGAGATCGCTGCATACTGTCGCCAGCACTGCCTGCTGCCTTTAGCAGCAAAGCAAAGGATT GGCCAGCTGATAATATGGAGAGAGGTGTTCCCAAGACACCACCTCCAGCCCCCTTCAGACTCAGACCCCG AGGCCTTCCAGGAACCTGAAGGGAGATATTTCTTACTAGTTGTCGGATTGCGACATTATTTGTTGTGCGT GCTGTTAGAAGCTGGAGGCTGTGCATCTAAAGCTACTGGGAACCCTGGTCCCGATTGTATCTATGTAGAT CAGGTCAGAGCGACCCTTCATCAGCTGGAAGGAGTAGACTCCCGCATAGAGGAACAGCTAGCCACATCCC CGGGGCCCTGCTTGTCTTGTGCTGACTGGTTCCTTGCTGCTCCACGTGAAAAGGCAGATAGTTTGACTAC TTCACCTATCCTCAGTCGGCTGCAGGGGCCTTCCAAAACAGCAGCCTCTCCAACATGCAGGAGAACCTTT TTCAGTGACTATTCCTTCAAGGCACGGAAGCCCAGTCCCTCCAGGATCGGTGGAGGACGTGAACCCACTG AAGGGGAAGAAAGTGCTGGTCTGAGCCCACATGCTACCCCAGATGCAGTACGGAAGCAAAGAGAATCCGA AGGCTCGGACGACAATGTGGCCTTGCTTAAGCTTGCTAGAAAGAAGTCAACACTTCCAAATCCGTTTCAT TTGGGAACTTCGAAAAAAGAACTTTCAGAAAAAGAGTTGGAAGTCTATGACATAATGAAATTGACCTCCG GTCCTGAGAATACACTCTTCCACTATGTTGCCTTGGAAACAGTGCAAGGCATCTTCATCACCCCCACCCA TGAAGAGGTGGCTCAGCTAGGTGGTTCCGTTCACTCTCAACTGATAAAGAATTTCCATCAATGTTGTCTC TCTATCCGTGCATTTTTCCAGCAGACGCTGAAGGAAGAGAAAAAGAAAGCGCTAAGTGATGGAGAGCATT CGGAGCCTACAAATTCAGTGTCTTCTCTGAGCCCTGTGAAAGAACATGGTGTGCTGTTTGAATGCTCACC TGAAAACTGGACTGATCAGAAAAAGACTCCACCAGTCATGTCATACTGGGTAGTAGGGCGGCTCTTTCTT AACCCAAAACCTCAGGAACTATATGTCTGTTTTCACGACTCAGTCTCAGAAATTGCCATTGAAATGGCAT TTAAATTGTTCTTTGGGTTAACGTTGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_175515 |
| Insert Size | 2829 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_175515.5, NP_780724.3 |
| RefSeq Size | 6387 bp |
| RefSeq ORF | 2829 bp |
| Locus ID | 380614 |
| UniProt ID | Q059U7 |
| Gene Summary | Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (PubMed:20067783, PubMed:21761479). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223978 | Intu (tGFP-tagged) - Mouse inturned planar cell polarity effector homolog (Drosophila) (Intu), (10ug) |
CNY 7,890.00 |
|
| MR223978 | Intu (Myc-DDK-tagged) - Mouse inturned planar cell polarity effector homolog (Drosophila) (Intu) |
CNY 6,904.00 |
|
| MR223978L3 | Lenti ORF clone of Intu (Myc-DDK-tagged) - Mouse inturned planar cell polarity effector homolog (Drosophila) (Intu) |
CNY 9,030.00 |
|
| MR223978L4 | Lenti ORF clone of Intu (mGFP-tagged) - Mouse inturned planar cell polarity effector homolog (Drosophila) (Intu) |
CNY 9,030.00 |
