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Ptprh (NM_207270) Mouse Untagged Clone
CAT＃: MC222937
Ptprh (untagged) - Mouse protein tyrosine phosphatase, receptor type, H (Ptprh), (10ug)
CNY 12,540.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | R-PTP-H; sap-1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222937 representing NM_207270
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCAGAGCTGGTGGGAACTGTGGGGTTTGGAGGAGCTTGGTGCTATTGGGTTTGTATGGTTGTTCTG TGGTCAGGGCAGCTGGTACCAGTGTCACAGTGGACAGGCATGCTCCTGCTTCTTCATACGAGTTTTCCAT GTGGGTAGAGAAAGATGGCGTCAGCAGCTCCCCACAGATTCCTGTAACCACCGCAGCCCCAAACCCAGTG AGAAACCTGAGGGTCGAAGGTCAAAACAACATCTCCATCAGCCTGAGCTGGGAGCCTCCTGATCAGTCCT CCCTGCAGGGCCTCACCTACTGGACCCAGTGCAGTAGACATGGTGGCCAAACTGAGACCCGGAACACAAC AGACACCAGTGTCACCGTGGATGGCCTTGATCCTGGGTCTTCATATGAATGTTCTGTGTGGGTGGAAAAG GATGGACTCTATAGCAAAAATGAGACTCTCAATACCAGCACAGCTCCAAACCCAGTGAGAAACCTGAGGG TCGAAGGTCAAAACAACATCTCCATCAGCCTGAGCTGGGAGCCTCCTGATCAGCCCTCCCTGCAGGGCCT CACCTACTGGGCCCAGTGCAGTAGACATGGTGGCCAAACTGAGACCCGGAACACAGCAGACACCAGTGTC ACCGTGGATGGACTTGATCCTGGGTCTTCATATGAATGTTCTGTGTGGGTGGAAAAGGATGGAGTCTATA GCACCAATGAGACTCTCAATACCAGCACAGCCCCAAACCCAGTGAGAAACCTGAGGGTCGAAGGTCAAAA CAACATCTCCATCAGCCTGAGCTGGGAGCCTCCTGATCAGCCCTCCCTGCAGGGCCTCACCTACTGGGCC CAGTGCAGTAGACATGGTGGCCAAACTGAGACCCGGAACACAACAGACACCAGTATTACCGTGGATGGAC TTGATCCTGGGTCTTCATATGAATGTTCTGTGTGGGTGGAAAAGGATGGAGTCTATAGCACCAATGAGAC TCTCAGTAACACCACAGCCCCAAACCCAGTGAGAAACCTGAGGGTCAAAAGTCAGAACAACTTCTCCATC AGCCTGAGCTGGGAGCCTCCTGATCAGCCCTCCCTGCAGGGCCTCATCTACTGGGCCCAGTGCAGTAGAC ATGGTGGCCAAACTGAGACCCGGAACACAACAGACACCAGTGTCACCGTGGATGGACTTGATCCTGGGTT TTTATATAAATGTTCTGTGTGGGTGGAAAAGGATGGAGTCTATAGCACCAATGAGACTCTCAATACCAGC ACAGTCCCCATTTCAGCCTCAAACCCAGTGAGAAACCTGAGGGTCGAAGGTCAGAACAACTTCTCCATCA GCCTGAGCTGGGAGCCTCCTGATCAGTCCTCCCTGCAGGGCCTCACCTACTGGGCCCAGTGCAGTAGACA TGGTGGCCAAACTGAGACCCGGAACACAGCAGACACCAGTGTCACCGTGGATGGCCTTGATCCTGGGTCT TCATATGAATGTTCTGTGTGGGTGGAAAAGGATGGAGTCTATAGCACCAATGAGACTCTCAATACCAGCA CAGTACCAGCTGCTGTCAACATCACCTCCTGCATCAGCACTTCTGGGGGATATGGGGTCCTCCTGACCTG GTCCTGCCCATCTGGGGGTTATGAGAGCTTTGAGGTAAAAGTGGGTAGGAAATGGCGCTCTGAAAATGGA TCTTTGTGTGGGAAGGGCGTGACCGTGTCAGATCTTGAGCCAGCTCAGTCCTACACAGCCACCGTCACGA CTGTCTTCAAGGACCTGAAGGCCCAGTCTCTCTCTACAACTTGCCACACAGAGAGTGCAGCCATCATTGC TGGAGCCATTGTGGGCATCCTCCTGCTTTTCATCCTGGTGGGTCTGCTGATTGTCTTCCTGAAGAGGAGG AGAAAGAAGAGACAGCCCAAGGAAGTGCCCAAGGATCTGGTGTGCAGCTGCCCAGGGGATATCCTGGCCA AAGACTTTGCTGACCATGTCAGGGAGAATGAGAAGGACAGCAACTGTGGATTTGCTGAGGAGTATCAGCA ACTGGCTCTGGAGGGCCAAGGCCAGTCTCAAATAACGGCATCGGCTCTAGAGAACAGATCCAAGAACCGC TACAGGAATGTACTGCCCTATGACTGGTCCCGGGTTCCCCTGCAGCCCCTCCAAGAGGAACCAGGCTCTG ACTATATCAACGCCAGCTTTATGCCTGGTCTCTGGAGCCCCAAGGAGTTCATTGCAACCCAGGGTCCCCT GCCTAACACTGTGGGTGATTTTTGGAGAATGGTCTGGGAACAGCAGAGCCACACCCTGGTTATGCTGACC AACTGCATGGAGTCTGGACGGGTGAAGTGTGAGCACTACTGGCCCTTGGATGCTCAGCCTTGCATTCATG GGCAGCTGCAGGTAATGTTGATTAGTGAGGAGGCGTCAGAAAACTGGACAGTGAGGCATCTTCAACTCTT CCATATGAAAGAACAGCAGACTCTCTCGTTGCGCCAATTCCACTACCTGGCCTGGCCAGACCATGGAGTT CCTTACTCCCCAGACCCCCTGCTGGCTTTCCGAAAGATGCTTCGGCAATGGATGGATCAGACCACGGATG GAGGTCCACCCATTGTGCATTGCAGTGCTGGTGTGGGCCGGACGGGCACCCTAATTGCACTGGATGTCCT GCTGCGGCAGCTGGAGTGTGAGGGGCTGGTGGGTCCCTTCAGCTTTGTGAAGAAGATGAGAGAGAGCCGG CCACTGATGGTGCAGACAGAGGCCCAGTATGTGTTCCTCCACCAGTGCATCTTGAAATCCCTCCAGAAGC CAGCTCCAGCCCTTGTCCCAGAGGAGGCAATGTATGAGAACGTGGCAAGCTTAGTTTATGAGAATGCATC TGCTATCATGGCCCATGAGTCTGAGTTCTCAGCTTCTGGGTGCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_207270 |
| Insert Size | 2916 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_207270.2, NP_997153.2 |
| RefSeq Size | 4020 bp |
| RefSeq ORF | 2916 bp |
| Locus ID | 545902 |
| UniProt ID | E9Q0N2 |
| Gene Summary | Protein phosphatase that may contribute to contact inhibition of cell growth and motility by mediating the dephosphorylation of focal adhesion-associated substrates and thus negatively regulating integrin-promoted signaling processes. Induces apoptotic cell death by at least two distinct mechanisms: inhibition of cell survival signaling mediated by PI 3-kinase, Akt, and ILK and activation of a caspase-dependent proapoptotic pathway. Inhibits the basal activity of LCK and its activation in response to TCR stimulation and TCR-induced activation of MAP kinase and surface expression of CD69. Inhibits TCR-induced tyrosine phosphorylation of LAT and ZAP70. Inhibits both basal activity of DOK1 and its CD2-induced tyrosine phosphorylation. Induces dephosphorylation of BCAR1, focal adhesion kinase and SRC. Reduces migratory activity of Jurkat cells (By similarity). Reduces tyrosine phosphorylation of CEACAM20 and thereby contributes to suppress the intestinal immune response (PubMed:26195794).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG215480 | Ptprh (tGFP-tagged) - Mouse protein tyrosine phosphatase receptor type H (Ptprh), (10ug) |
CNY 9,410.00 |
|
| MR215480 | Ptprh (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, receptor type, H (Ptprh) |
CNY 7,112.00 |
|
| MR215480L3 | Lenti ORF clone of Ptprh (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, receptor type, H (Ptprh) |
CNY 10,450.00 |
|
| MR215480L4 | Lenti ORF clone of Ptprh (mGFP-tagged) - Mouse protein tyrosine phosphatase, receptor type, H (Ptprh) |
CNY 10,450.00 |
