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Taok1 (NM_144825) Mouse Untagged Clone
CAT＃: MC223157
Taok1 (untagged) - Mouse TAO kinase 1 (Taok1), (10ug)
CNY 12,920.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2810468K05Rik; AU020252; D130018F14Rik; Map3k16; Markk; mKIAA1361; Psk2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223157 representing NM_144825
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCATCAACTAACAGAGCAGGCAGTCTAAAGGACCCTGAAATTGCAGAGCTCTTCTTCAAAGAAGATC CGGAAAAGCTCTTCACAGATCTCAGAGAAATCGGCCATGGGAGCTTTGGAGCAGTATATTTTGCACGAGA TGTGCGTACTAATGAAGTGGTGGCCATCAAGAAAATGTCTTATAGTGGAAAGCAGTCTACTGAGAAATGG CAGGATATTATTAAGGAAGTCAAGTTTCTACAAAGAATAAAACATCCCAACAGTATAGAATACAAAGGCT GCTATTTACGTGAACACACAGCATGGCTTGTAATGGAATATTGTTTAGGATCTGCTTCAGATTTATTAGA AGTTCATAAAAAGCCATTACAAGAAGTGGAAATAGCAGCAATTACACATGGTGCTCTCCAGGGACTAGCT TATTTACATTCTCATACCATGATCCATAGAGATATCAAAGCAGGAAATATCCTTCTGACAGAACCAGGCC AAGTGAAACTTGCTGACTTTGGATCTGCTTCCATGGCTTCCCCTGCCAATTCTTTTGTGGGAACACCATA TTGGATGGCCCCAGAAGTAATTTTAGCCATGGATGAAGGACAGTATGATGGCAAAGTTGATGTATGGTCT CTTGGAATAACGTGTATTGAATTAGCCGAGAGGAAGCCTCCTTTATTTAATATGAATGCAATGAGTGCCT TATATCACATAGCCCAAAATGAATCCCCTACACTACAATCTAATGAATGGTCTGATTATTTTCGAAACTT TGTAGATTCTTGCCTCCAGAAAATCCCTCAAGATCGCCCTACATCAGAGGAACTTTTAAAGCACATGTTT GTTCTTCGAGAGCGCCCTGAAACAGTGTTAATAGATCTTATTCAAAGGACAAAGGATGCAGTAAGAGAGC TGGACAATCTGCAGTATCGAAAGATGAAGAAACTCCTTTTCCAGGAGGCACATAATGGGCCAGCGGTAGA AGCACAGGAAGAAGAGGAGGAGCAAGATCATGGTGTTGGCCGAACAGGAACAGTGAATAGTGTTGGAAGC AATCAGTCTATCCCTAGTATGTCTATCAGTGCCAGCAGTCAAAGCAGCAGTGTTAATAGTCTTCCAGATG CATCAGATGACAAGAGTGAGCTAGACATGATGGAGGGAGACCATACAGTGATGTCTAACAGTTCTGTCAT CCACTTAAAACCTGAGGAGGAAAATTACCAGGAAGAAGGAGATCCTAGAACAAGAGCATCAGACCCACAG TCTCCCCCTCAGGTGTCTCGTCACAAGTCACATTATCGTAATAGAGAACACTTTGCAACCATACGAACAG CATCACTGGTTACAAGACAGATGCAAGAACATGAGCAGGACTCTGAACTTAGAGAACAGATGTCTGGTTA TAAGCGGATGAGGCGACAGCATCAAAAGCAGCTGATGACGCTGGAAAATAAACTGAAGGCAGAGATGGAC GAACATCGGCTCAGATTAGACAAAGATCTTGAAACTCAGCGTAACAATTTCGCTGCAGAAATGGAGAAAC TTATTAAGAAACACCAAGCTGCTATGGAAAAAGAGGCTAAAGTGATGGCCAATGAGGAGAAAAAATTCCA GCAACACATTCAGGCTCAACAGAAAAAAGAACTGAATAGCTTTTTGGAGTCTCAAAAAAGAGAATATAAA CTTCGCAAAGAGCAGCTTAAGGAGGAGCTGAATGAAAACCAGAGCACACCTAAAAAAGAAAAGCAGGAAT GGCTTTCAAAGCAGAAGGAGAATATACAGCATTTTCAGGCAGAAGAAGAAGCTAATCTTCTTCGACGTCA AAGGCAGTATCTAGAGCTAGAATGTCGTCGCTTCAAAAGAAGAATGTTACTTGGGCGACATAACTTGGAA CAGGACCTTGTCAGGGAGGAGTTAAACAAAAGGCAGACTCAAAAGGACTTGGAACATGCAATGCTATTGC GACAGCATGAATCAATGCAAGAACTGGAGTTTCGCCATCTCAACACTATTCAGAAGATGCGCTGTGAGTT GATCAGACTGCAGCATCAAACTGAGCTCACTAACCAGCTAGAGTACAATAAGAGAAGGGAACGGGAACTG AGGCGAAAACATGTCATGGAAGTTCGACAACAACCTAAGAGTCTGAAGTCTAAAGAACTCCAAATAAAAA AGCAGTTTCAGGATACCTGCAAAATTCAAACCAGACAGTACAAAGCATTAAGGAATCACCTACTGGAGAC TACACCAAAGAGTGAGCACAAAGCTGTTTTGAAAAGACTCAAGGAGGAACAGACTCGAAAGTTAGCCATC TTGGCTGAGCAGTATGATCATAGCATTAATGAAATGCTCTCCACACAAGCTCTGCGTTTGGATGAAGCAC AGGAAGCAGAATGCCAGGTTCTGAAGATGCAGCTGCAGCAGGAACTGGAGCTGCTGAATGCTTATCAGAG CAAAATAAAGATGCAAGCTGAGGCCCAACATGATCGAGAGCTTCGAGAGCTGGAACAGAGGGTCTCCCTT CGCAGAGCGCTCTTAGAACAAAAGATTGAAGAAGAGATGTTGGCTTTGCAGAATGAACGCACAGAACGAA TACGTAGCCTGCTCGAGCGTCAAGCCAGAGAAATTGAAGCATTTGACTCTGAAAGCATGAGATTAGGTTT TAGTAACATGGTCCTTTCTAATCTCTCCCCTGAGGCATTCAGCCACAGCTACCCAGGAGCTTCTAGTTGG TCTCACAATCCTACTGGGGGTCCAGGACCTCACTGGGGTCATCCCATGGGTGGCACACCACAAGCTTGGG GTCATCCGATGCAAGGTGGACCCCAACCATGGGGTCATCCCTCAGGGCCAATGCAAGGGGTACCTCGAGG TAGCAGTATGGGAGTCCGCAATAGCCCCCAGGCTTTGAGGCGGACAGCTTCTGGGGGACGGACGGAACAG GGCATGAGCAGAAGCACGAGTGTCACTTCACAAATATCCAATGGGTCACACATGTCTTACACATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_144825 |
| Insert Size | 3006 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_144825.2, NP_659074.2 |
| RefSeq Size | 12411 bp |
| RefSeq ORF | 3006 bp |
| Locus ID | 216965 |
| UniProt ID | Q5F2E8 |
| Gene Summary | Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis: regulates apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG218174 | Taok1 (tGFP-tagged) - Mouse TAO kinase 1 (Taok1), (10ug) |
CNY 9,220.00 |
|
| MR218174 | Taok1 (Myc-DDK-tagged) - Mouse TAO kinase 1 (Taok1) |
CNY 6,968.00 |
|
| MR218174L3 | Lenti ORF clone of Taok1 (Myc-DDK-tagged) - Mouse TAO kinase 1 (Taok1) |
CNY 10,260.00 |
|
| MR218174L4 | Lenti ORF clone of Taok1 (mGFP-tagged) - Mouse TAO kinase 1 (Taok1) |
CNY 10,260.00 |
