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Grin2c (NM_010350) Mouse Untagged Clone
CAT＃: MC224027
Grin2c (untagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c), (10ug)
CNY 15,870.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | GluN2C; NMDAR2C; NR2C |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224027 representing NM_010350
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGTGGAGCCCTGGGGCCCGCCCTGCTTCTCACTTCACTCCTTGGTGCTTGGGCAGGGCTGGGCGCAG GGCAGGGAGAACAGGCCGTGACCGTGGCGGTGGTGTTTGGCAGCTCTGGGCCACTGCAGGCCCAGGCCCG GACTCGTCTCACCCCGCAGAACTTCCTGGACTTGCCTCTGGAGATCCAGCCACTCACCATCGGGGTCAAC AATACCAACCCCAGCAGCATCCTCACCCAAATCTGTGGGCTCCTGGGTGCCGCCCGAGTCCACGGCATCG TCTTTGAGGACAACGTGGACACTGAGGCCGTGGCTCAGCTGCTGGATTTCGTCTCCTCTCAGACCCACGT GCCCATCCTCAGCATCAGTGGAGGTTCTGCTGTGGTCCTCACCCCCAAGGAGCCAGGCTCCGCCTTTCTA CAGCTGGGCGTGTCCCTGGAGCAGCAGCTGCAGGTGCTGTTCAAGGTGCTGGAGGAATACGACTGGAGCG CGTTCGCTGTCATCACCAGCCTGCACCCGGGCCACGCGCTCTTCCTCGAGGGCGTGCGCGCCGTCGCCGA CGCCAGCTACCTGAGCTGGCGGCTGCTGGACGTGCTCACGCTGGAGCTGGGCCCCGGTGGGCCGCGAGCG CGCACTCAGCGCTTACTGCGCCAGGTCGACGCCCCGGTGCTGGTGGCCTACTGCTCCCGTGAAGAGGCGG AGGTGCTCTTCGCGGAGGCTGCACAGGCTGGCTTGGTGGGACCCGGTCACGTGTGGTTAGTACCTAATCT GGCGCTGGGAAGCACCGACGCTCCCCCTGCAGCCTTCCCAGTGGGCCTCATCAGTGTGGTCACCGAGAGT TGGCGCCTTAGCCTACGCCAGAAAGTCCGCGACGGTGTAGCCATTCTGGCCCTCGGTGCCCACAGCTACC GACGCCAGTACGGTACCCTTCCAGCCCCGGCTGGAGACTGCCGAAGCCACCCAGGACCCGTCAGCCCTGC CAGGGAGGCTTTCTACAGGCATCTGCTGAATGTCACCTGGGAAGGCCGAGACTTCTCTTTTAGCCCTGGT GGGTACCTGGTCCAGCCCACAATGGTTGTGATCGCTCTCAACCGGCATCGCCTCTGGGAGATGGTGGGAC GGTGGGATCATGGGGTCCTGTACATGAAGTATCCAGTATGGCCTCGCTACAGCACTTCTCTGCAGCCTGT GGTGGACAGCCGGCACCTGACAGTGGCCACACTGGAAGAAAGGCCTTTTGTCATTGTGGAGAGCCCTGAC CCTGGCACAGGTGGCTGTGTTCCCAACACTGTGCCCTGCCGTAGACAGAGCAACCACACCTTCAGCAGCG GGGATATAACCCCCTACACCAAGCTCTGTTGTAAGGGCTTCTGCATCGACATCCTCAAGAAGCTGGCCAA GGTGGTCAAGTTCTCCTACGACTTGTACCTGGTGACCAACGGCAAGCACGGCAAGAGGGTTCGTGGTGTG TGGAATGGTATGATCGGTGAGGTATACTACAAGCGGGCAGACATGGCCATCGGCTCCCTCACCATCAATG AAGAGCGCTCAGAGATTATAGACTTCTCTGTGCCTTTTGTGGAGACCGGCATCAGTGTGATGGTGGCAAG GAGCAACGGCACCGTCTCCCCCTCGGCTTTTCTGGAGCCCTACAGCCCTGCCGTGTGGGTGATGATGTTT GTAATGTGCCTCACGGTGGTTGCCATCACTGTCTTCATGTTCGAGTATTTCAGCCCTGTCAGCTACAACC AGAATCTCACCAAGGGCAAGAAGTCAGGTGGACCATCCTTCACCATTGGCAAGTCCGTGTGGTTGCTGTG GGCACTGGTCTTCAACAACTCTGTTCCCATCGAGAACCCCCGGGGCACCACCAGCAAGATCATGGTCCTG GTGTGGGCCTTCTTCGCTGTCATCTTCCTCGCTAGCTACACGGCCAATCTGGCAGCCTTCATGATCCAGG AACAATACATCGACACTGTGTCGGGCCTTAGTGACAAGAAGTTTCAGCGGCCTCAAGACCAATACCCACC CTTCCGTTTTGGCACGGTACCTAATGGCAGCACAGAGAGGAACATTCGTAGCAACTATCGTGACATGCAC ACTCACATGGTCAAGTTCAACCAGCGCTCGGTGGAGGATGCTCTCACAAGCCTGAAGATGGGGAAGCTGG ACGCCTTCATCTATGATGCCGCCGTCCTCAACTACATGGCGGGCAAGGACGAAGGCTGCAAGCTGGTCAC CATTGGGTCTGGCAAAGTCTTTGCCACCACTGGCTATGGCATTGCCATGCAGAAAGACTCCCACTGGAAG CGGGCCATAGACCTGGCGCTCCTGCAGTTCCTGGGGGATGGGGAGACACAGAAGTTGGAGACAGTGTGGC TCTCAGGGATCTGCCATAACGAGAAGAACGAGGTGATGAGCAGCAAGCTGGACATTGACAACATGGCGGG CGTCTTCTACATGCTGTTGGTGGCCATGGGGCTGGCCCTTCTGGTCTTTGCCTGGGAGCACCTGGTCTAC TGGAAACTTCGACACTCAGTGCCCAGCTCATCCCAGCTGGACTTCCTGCTGGCTTTCAGCAGGGGCATCT ACAGCTGCTTCAACGGGGTACAGAGCCTTCCGAGCCCTGCGCGGCCGCCCAGCCCGGACCTTACAGCAGG CTCAGCCCAGGCCAATGTGCTGAAGATGCTGCAGGCGGCTCGAGACATGGTGAGCACAGCGGACGTGAGC GGCTCTTTGGACCGCGCCACTCGTACCATCGAGAACTGGGGCAACAATCGCCGCGCGCCTGCTCCCACCA CCTCCGGCCCGCGGTCATGCACCCCGGGTCCTCCGGGACAACCGAGTCCCAGCGGCTGGCGGCCTCCCGG TGGGGGCCGCACCCCGCTAGCGCGCCGGGCCCCGCAGCCTCCCGCTCGCCCCGCGACCTGCGCAGGGTCG CCTCAGCCCGACGTGTCCCGAGCATCCTGCAGGCACGCTTGGGATGCGCGGTGGCCAGTGCGAGTCGGGC ATCAGGGATCGCACCTCTCGGCCTCCGAGCGGCGCGCGCTCCCGGAGCGCTCCCTGTTGCACGCGCACTG CCACTACAGTTCCTTCCCTCGAGCAGAGAGGTCAGGGCGCCCATTTCTCCCGCTATTCCCGGAGCCCCCG GAGCCCGACGACCTGCCGCTGCTCGGGCCGGAACAGCTGGCTCGGCGGGAGGCTCTGCTGCGCGCGGCCT GGGCCAGGGGCCCGCGCCCTCGGCACGCTTCCCTGCCCAGCTCCGTGGCAGAAGCCTTCACTCGATCCAA CCCTCTGCCTGCCAGGTGTACCGGTCACGCCTGCGCTTGCCCATGTCCCCAAAGCCGGCCATCCTGCCGG CACGTGGCTCAAACACAGTCGTTGCGGCTGCCATCCTACCGGGAGGCCTGTGTGGAGGGCGTGCCAGCAG GGGTGGCCGCCACCTGGCAGCCCAGACAGCATGTCTGCCTGCACACCCATACCCACCTGCCGTTCTGCTG GGGGACTGTCTGCCGTCACCCTCCACCCTGTTCCAGCCACAGTCCCTGGCTCATTGGAACTTGGGAGCCT CCATCACACAGAGGCAGGACCCTGGGGCTAGGTACAGGCTACAGGGACAGTGGGGTGCTAGAAGAGGTCA GCAGGGAAGCTTGTGGGACACAAGGGTTTCCAAGGTCCTGCACCTGGAGGCGGATCTCCAGCCTGGAATC AGAAGTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_010350 |
| Insert Size | 3720 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_010350.2, NP_034480.2 |
| RefSeq Size | 4895 bp |
| RefSeq ORF | 3720 bp |
| Locus ID | 14813 |
| UniProt ID | Q01098 |
| Gene Summary | Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:1377365). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:1377365). Plays a role in regulating the balance between excitatory and inhibitory activity of pyramidal neurons in the prefrontal cortex (PubMed:27922130). Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (PubMed:8987814).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG222676 | Grin2c (tGFP-tagged) - Mouse glutamate receptor ionotropic NMDA2C (epsilon 3) (Grin2c), (10ug) |
CNY 10,550.00 |
|
| MR222676 | Grin2c (Myc-DDK-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c) |
CNY 8,632.00 |
|
| MR222676L3 | Lenti ORF clone of Grin2c (Myc-DDK-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c) |
CNY 11,500.00 |
|
| MR222676L4 | Lenti ORF clone of Grin2c (mGFP-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c) |
CNY 11,500.00 |
