Grin2c (NM_010350) Mouse Tagged ORF Clone
CAT#: MG222676
- TrueORF®
Grin2c (tGFP-tagged) - Mouse glutamate receptor ionotropic NMDA2C (epsilon 3) (Grin2c), (10ug)
ORF Plasmid: DDK
"NM_010350" in other vectors (4)
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CNY 10,550.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | GluN2C; NMDAR2C; NR2C |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MG222676 representing NM_010350
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGTGGAGCCCTGGGGCCCGCCCTGCTTCTCACTTCACTCCTTGGTGCTTGGGCAGGGCTGGGCGCAG GGCAGGGAGAACAGGCCGTGACCGTGGCGGTGGTGTTTGGCAGCTCTGGGCCACTGCAGGCCCAGGCCCG GACTCGTCTCACCCCGCAGAACTTCCTGGACTTGCCTCTGGAGATCCAGCCACTCACCATCGGGGTCAAC AATACCAACCCCAGCAGCATCCTCACCCAAATCTGTGGGCTCCTGGGTGCCGCCCGAGTCCACGGCATCG TCTTTGAGGACAACGTGGACACTGAGGCCGTGGCTCAGCTGCTGGATTTCGTCTCCTCTCAGACCCACGT GCCCATCCTCAGCATCAGTGGAGGTTCTGCTGTGGTCCTCACCCCCAAGGAGCCAGGCTCCGCCTTTCTA CAGCTGGGCGTGTCCCTGGAGCAGCAGCTGCAGGTGCTGTTCAAGGTGCTGGAGGAATACGACTGGAGCG CGTTCGCTGTCATCACCAGCCTGCACCCGGGCCACGCGCTCTTCCTCGAGGGCGTGCGCGCCGTCGCCGA CGCCAGCTACCTGAGCTGGCGGCTGCTGGACGTGCTCACGCTGGAGCTGGGCCCCGGTGGGCCGCGAGCG CGCACTCAGCGCTTACTGCGCCAGGTCGACGCCCCGGTGCTGGTGGCCTACTGCTCCCGTGAAGAGGCGG AGGTGCTCTTCGCGGAGGCTGCACAGGCTGGCTTGGTGGGACCCGGTCACGTGTGGTTAGTACCTAATCT GGCGCTGGGAAGCACCGACGCTCCCCCTGCAGCCTTCCCAGTGGGCCTCATCAGTGTGGTCACCGAGAGT TGGCGCCTTAGCCTACGCCAGAAAGTCCGCGACGGTGTAGCCATTCTGGCCCTCGGTGCCCACAGCTACC GACGCCAGTACGGTACCCTTCCAGCCCCGGCTGGAGACTGCCGAAGCCACCCAGGACCCGTCAGCCCTGC CAGGGAGGCTTTCTACAGGCATCTGCTGAATGTCACCTGGGAAGGCCGAGACTTCTCTTTTAGCCCTGGT GGGTACCTGGTCCAGCCCACAATGGTTGTGATCGCTCTCAACCGGCATCGCCTCTGGGAGATGGTGGGAC GGTGGGATCATGGGGTCCTGTACATGAAGTATCCAGTATGGCCTCGCTACAGCACTTCTCTGCAGCCTGT GGTGGACAGCCGGCACCTGACAGTGGCCACACTGGAAGAAAGGCCTTTTGTCATTGTGGAGAGCCCTGAC CCTGGCACAGGTGGCTGTGTTCCCAACACTGTGCCCTGCCGTAGACAGAGCAACCACACCTTCAGCAGCG GGGATATAACCCCCTACACCAAGCTCTGTTGTAAGGGCTTCTGCATCGACATCCTCAAGAAGCTGGCCAA GGTGGTCAAGTTCTCCTACGACTTGTACCTGGTGACCAACGGCAAGCACGGCAAGAGGGTTCGTGGTGTG TGGAATGGTATGATCGGTGAGGTATACTACAAGCGGGCAGACATGGCCATCGGCTCCCTCACCATCAATG AAGAGCGCTCAGAGATTATAGACTTCTCTGTGCCTTTTGTGGAGACCGGCATCAGTGTGATGGTGGCAAG GAGCAACGGCACCGTCTCCCCCTCGGCTTTTCTGGAGCCCTACAGCCCTGCCGTGTGGGTGATGATGTTT GTAATGTGCCTCACGGTGGTTGCCATCACTGTCTTCATGTTCGAGTATTTCAGCCCTGTCAGCTACAACC AGAATCTCACCAAGGGCAAGAAGTCAGGTGGACCATCCTTCACCATTGGCAAGTCCGTGTGGTTGCTGTG GGCACTGGTCTTCAACAACTCTGTTCCCATCGAGAACCCCCGGGGCACCACCAGCAAGATCATGGTCCTG GTGTGGGCCTTCTTCGCTGTCATCTTCCTCGCTAGCTACACGGCCAATCTGGCAGCCTTCATGATCCAGG AACAATACATCGACACTGTGTCGGGCCTTAGTGACAAGAAGTTTCAGCGGCCTCAAGACCAATACCCACC CTTCCGTTTTGGCACGGTACCTAATGGCAGCACAGAGAGGAACATTCGTAGCAACTATCGTGACATGCAC ACTCACATGGTCAAGTTCAACCAGCGCTCGGTGGAGGATGCTCTCACAAGCCTGAAGATGGGGAAGCTGG ACGCCTTCATCTATGATGCCGCCGTCCTCAACTACATGGCGGGCAAGGACGAAGGCTGCAAGCTGGTCAC CATTGGGTCTGGCAAAGTCTTTGCCACCACTGGCTATGGCATTGCCATGCAGAAAGACTCCCACTGGAAG CGGGCCATAGACCTGGCGCTCCTGCAGTTCCTGGGGGATGGGGAGACACAGAAGTTGGAGACAGTGTGGC TCTCAGGGATCTGCCATAACGAGAAGAACGAGGTGATGAGCAGCAAGCTGGACATTGACAACATGGCGGG CGTCTTCTACATGCTGTTGGTGGCCATGGGGCTGGCCCTTCTGGTCTTTGCCTGGGAGCACCTGGTCTAC TGGAAACTTCGACACTCAGTGCCCAGCTCATCCCAGCTGGACTTCCTGCTGGCTTTCAGCAGGGGCATCT ACAGCTGCTTCAACGGGGTACAGAGCCTTCCGAGCCCTGCGCGGCCGCCCAGCCCGGACCTTACAGCAGG CTCAGCCCAGGCCAATGTGCTGAAGATGCTGCAGGCGGCTCGAGACATGGTGAGCACAGCGGACGTGAGC GGCTCTTTGGACCGCGCCACTCGTACCATCGAGAACTGGGGCAACAATCGCCGCGCGCCTGCTCCCACCA CCTCCGGCCCGCGGTCATGCACCCCGGGTCCTCCGGGACAACCGAGTCCCAGCGGCTGGCGGCCTCCCGG TGGGGGCCGCACCCCGCTAGCGCGCCGGGCCCCGCAGCCTCCCGCTCGCCCCGCGACCTGCGCAGGGTCG CCTCAGCCCGACGTGTCCCGAGCATCCTGCAGGCACGCTTGGGATGCGCGGTGGCCAGTGCGAGTCGGGC ATCAGGGATCGCACCTCTCGGCCTCCGAGCGGCGCGCGCTCCCGGAGCGCTCCCTGTTGCACGCGCACTG CCACTACAGTTCCTTCCCTCGAGCAGAGAGGTCAGGGCGCCCATTTCTCCCGCTATTCCCGGAGCCCCCG GAGCCCGACGACCTGCCGCTGCTCGGGCCGGAACAGCTGGCTCGGCGGGAGGCTCTGCTGCGCGCGGCCT GGGCCAGGGGCCCGCGCCCTCGGCACGCTTCCCTGCCCAGCTCCGTGGCAGAAGCCTTCACTCGATCCAA CCCTCTGCCTGCCAGGTGTACCGGTCACGCCTGCGCTTGCCCATGTCCCCAAAGCCGGCCATCCTGCCGG CACGTGGCTCAAACACAGTCGTTGCGGCTGCCATCCTACCGGGAGGCCTGTGTGGAGGGCGTGCCAGCAG GGGTGGCCGCCACCTGGCAGCCCAGACAGCATGTCTGCCTGCACACCCATACCCACCTGCCGTTCTGCTG GGGGACTGTCTGCCGTCACCCTCCACCCTGTTCCAGCCACAGTCCCTGGCTCATTGGAACTTGGGAGCCT CCATCACACAGAGGCAGGACCCTGGGGCTAGGTACAGGCTACAGGGACAGTGGGGTGCTAGAAGAGGTCA GCAGGGAAGCTTGTGGGACACAAGGGTTTCCAAGGTCCTGCACCTGGAGGCGGATCTCCAGCCTGGAATC AGAAGTG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG222676 representing NM_010350
Red=Cloning site Green=Tags(s) MGGALGPALLLTSLLGAWAGLGAGQGEQAVTVAVVFGSSGPLQAQARTRLTPQNFLDLPLEIQPLTIGVN NTNPSSILTQICGLLGAARVHGIVFEDNVDTEAVAQLLDFVSSQTHVPILSISGGSAVVLTPKEPGSAFL QLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLEGVRAVADASYLSWRLLDVLTLELGPGGPRA RTQRLLRQVDAPVLVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALGSTDAPPAAFPVGLISVVTES WRLSLRQKVRDGVAILALGAHSYRRQYGTLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWEGRDFSFSPG GYLVQPTMVVIALNRHRLWEMVGRWDHGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPD PGTGGCVPNTVPCRRQSNHTFSSGDITPYTKLCCKGFCIDILKKLAKVVKFSYDLYLVTNGKHGKRVRGV WNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMF VMCLTVVAITVFMFEYFSPVSYNQNLTKGKKSGGPSFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVL VWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMH THMVKFNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWK RAIDLALLQFLGDGETQKLETVWLSGICHNEKNEVMSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVY WKLRHSVPSSSQLDFLLAFSRGIYSCFNGVQSLPSPARPPSPDLTAGSAQANVLKMLQAARDMVSTADVS GSLDRATRTIENWGNNRRAPAPTTSGPRSCTPGPPGQPSPSGWRPPGGGRTPLARRAPQPPARPATCAGS PQPDVSRASCRHAWDARWPVRVGHQGSHLSASERRALPERSLLHAHCHYSSFPRAERSGRPFLPLFPEPP EPDDLPLLGPEQLARREALLRAAWARGPRPRHASLPSSVAEAFTRSNPLPARCTGHACACPCPQSRPSCR HVAQTQSLRLPSYREACVEGVPAGVAATWQPRQHVCLHTHTHLPFCWGTVCRHPPPCSSHSPWLIGTWEP PSHRGRTLGLGTGYRDSGVLEEVSREACGTQGFPRSCTWRRISSLESEV TRTRPLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_010350 |
ORF Size | 3717 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_010350.2, NP_034480.2 |
RefSeq Size | 4895 bp |
RefSeq ORF | 3720 bp |
Locus ID | 14813 |
UniProt ID | Q01098 |
Gene Summary | Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:1377365). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:1377365). Plays a role in regulating the balance between excitatory and inhibitory activity of pyramidal neurons in the prefrontal cortex (PubMed:27922130). Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (PubMed:8987814).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC224027 | Grin2c (untagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c), (10ug) |
CNY 15,870.00 |
|
MR222676 | Grin2c (Myc-DDK-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c) |
CNY 8,632.00 |
|
MR222676L3 | Lenti ORF clone of Grin2c (Myc-DDK-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c) |
CNY 11,500.00 |
|
MR222676L4 | Lenti ORF clone of Grin2c (mGFP-tagged) - Mouse glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Grin2c) |
CNY 11,500.00 |