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Abcc4 (NM_001163675) Mouse Untagged Clone
CAT＃: MC224154
Abcc4 (untagged) - Mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), transcript variant 2, (10ug)
CNY 16,530.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABCC4-N1; D630049P08Rik; MOATB; MRP4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224154 representing NM_001163675
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTTCTCAGTGCTTCCAGAAGATCGCTCAAAGCACCTCGGAGAGGAGCTTCAACGGTACTGGGATAAAG AACTTCTGCGAGCCAAGAAGGACTCGAGGAAGCCCTCCTTAACAAAGGCAATCATAAAGTGTTACTGGAA GTCTTACCTGATTTTGGGAATTTTTACGTTAATTGAGGAGGGCACTCGAGTAGTTCAGCCCTTATTTTTA GGGAAAATTATTGAATATTTTGAGAAGTATGACCCCGACGACTCGGTGGCTTTGCATACAGCTTATGGCT ACGCAGCAGTGCTGTCCATGTGCACGCTCATCCTGGCCATACTACATCATTTGTACTTCTACCACGTGCA GTGCGCCGGGATGAGGCTGCGGGTTGCCATGTGCCACATGATTTACCGGAAGGCACTCCGGTTAAGTAAC TCGGCCATGGGGAAGACAACCACAGGCCAGATAGTTAACCTGCTGTCCAACGACGTGAACAAATTCGACC AAGTGACAATCTTCTTGCACTTTCTGTGGGCAGGGCCGCTGCAGGCCATCGCGGTAACCGTCCTCCTCTG GGTGGAGATAGGAATCTCCTGCCTGGCGGGCTTGGCCGTTCTGGTTATTCTTCTGCCTCTGCAAAGCTGC ATCGGGAAGCTGTTCTCGTCACTGCGGAGTAAAACTGCGGCTTTCACGGATGCCAGGATCCGGACCATGA ATGAAGTCATAACAGGCATGAGGATAATAAAGATGTATGCGTGGGAGAAATCGTTTGCTGACCTCATTGC CAATCTGAGAAAGAAGGAGATTTCCAAGATTCTGGGCAGCTCCTACCTCAGAGGGATGAACATGGCGTCG TTTTTCATCGCAAACAAAGTCATCCTGTTCGTGACCTTCACTAGCTACGTGCTGCTTGGCAATGAGATTA CAGCTAGCCACGTGTTTGTGGCCATGACTCTGTACGGTGCCGTTCGGTTGACAGTCACCCTCTTCTTCCC GTCAGCCATTGAGAGAGGGTCAGAGGCCATCGTCAGCATTCGGAGGATCAAGAACTTTCTGTTACTCGAT GAACTACCACAGCGCAAAGCCCATGTACCATCTGATGGCAAAGCCATTGTCCACGTGCAAGATTTCACCG CTTTCTGGGACAAGGCACTAGACAGTCCAACCCTGCAAGGTCTTTCCTTTATTGCCAGGCCTGGTGAGTT GTTAGCCGTGGTTGGCCCAGTTGGAGCAGGCAAGTCGTCGCTGTTGAGCGCAGTGCTGGGTGAGCTGCCT CCTGCCAGCGGGCTGGTCAGCGTGCACGGGAGGATCGCCTACGTTTCTCAGCAGCCCTGGGTGTTCTCGG GCACCGTGAGGAGCAATATTTTATTTGGGAAGAAATATGAGAAGGAGCGATATGAGAAAGTGATCAAGGC CTGTGCTCTGAAGAAGGACCTGCAGCTTCTGGAGGACGGGGATCTGACGGTTATAGGAGACCGGGGAGCC ACGCTGAGTGGAGGCCAGAAAGCTCGGGTGAACCTGGCACGGGCCGTCTACCAGGACGCCGACATCTACC TCCTTGATGATCCGCTCAGCGCTGTCGATGCAGAAGTGGGCAAGCACCTGTTCCAACTGTGTATCTGTCA GGCGTTGCACGAGAAGATCACCATTTTAGTGACTCACCAGTTACAGTACCTCAAAGCTGCAAGCCACATC CTCATACTCAAAGATGGTGAGATGGTGCAGAAGGGGACTTACACGGAGTTTCTGAAATCTGGTGTAGATT TTGGCTCCCTGTTAAAGAAAGAAAACGAGGAAGCAGAGCCCTCCACAGCCCCAGGAACCCCGACACTCAG GAAACGAACCTTCTCCGAGGCCTCAATTTGGTCTCAGCAGTCATCCAGACCCTCGTTGAAAGACGGGGCC CCAGAGGGCCAAGACGCAGAGAACACGCAGGCAGTGCAACCCGAGGAGAGCCGTTCGGAAGGGAGAATCG GCTTCAAGGCCTACAAGAATTACTTCTCGGCGGGCGCATCCTGGTTCTTCATCATTTTCCTTGTGCTGCT TAACATGGTGGGCCAGGTTTTCTATGTTCTTCAGGACTGGTGGCTTTCCCACTGGGCGAACAAGCAAGGT GCACTGAACAACACCAGAAATGCGAATGGAAATATAACGGAGACCCTAGACCTCAGCTGGTACTTAGGAA TTTACGCAGGTCTAACTGCGGTCACCGTCCTTTTTGGCATAGCGAGATCCCTACTGGTGTTCTATATCCT TGTGAACGCTTCCCAGACTTTGCACAACAGGATGTTTGAGTCCATACTGAAGGCTCCCGTGTTGTTCTTC GACAGAAATCCAATCGGGAGGATTTTAAATCGTTTCTCCAAAGACATCGGACACATGGATGATTTGCTTC CCCTGACGTTCCTGGACTTCATCCAGACGTTGCTCCTCGTCGTAAGTGTGATCGCTGTGGCCGCGGCCGT GATCCCTTGGATCCTCATACCATTGGTTCCGCTCTCAGTCGTCTTCCTGGTTCTTCGGAGATACTTCTTA GAGACGTCACGGGATGTCAAGCGCCTGGAATCCACAACACGGAGCCCGGTATTCTCCCATTTATCGTCCT CCCTCCAGGGACTCTGGACCATCCGGGCTTACAAAGCTGAGGAGAGGTGTCAGGAGCTGTTTGATGCACA CCAGGACTTGCATTCAGAGGCTTGGTTCTTGTTCCTGACGACATCGAGATGGTTCGCTGTGCGTCTGGAC GCCATCTGCGCCATCTTTGTAATCGTCGTTGCCTTCGGGTCCCTTGTTCTGGCGAAGACTTTGAATGCTG GGCAGGTTGGCCTGGCCTTGTCCTACGCCCTCACACTCATGGGGATGTTCCAGTGGTCTGTGCGACAGAG CGCCGAAGTAGAGAATATGATGATTTCAGTGGAGAGAGTGATTGAGTACACGGACCTAGAGAAGGAGGCG CCTTGGGAGTGCAAGAAGCGCCCACCCCCAGGCTGGCCCCACGAGGGAGTCATCGTCTTCGACAATGTGA ACTTCACCTACAGCTTAGATGGGCCTCTGGTTCTGAAGCACCTGACTGCGCTCATCAAGTCCAGGGAAAA GGTTGGAATTGTGGGCAGAACCGGAGCTGGGAAAAGCTCCCTCATCTCGGCCCTCTTCAGGCTGTCAGAA CCCGAGGGGAAAATCTGGATCGATAAGATCTTGACAACCGAAATTGGGCTTCACGACTTAAGGAAGAAAA TGTCAATCATACCACAGGAACCTGTTCTGTTCACTGGAACCATGAGGAAAAACCTGGACCCCTTCAATGA GCACACGGACGAGGAGCTGTGGAGGGCCTTGGAGGAGGTACAACTTAAAGAGGCCATTGAAGATCTTCCT GGAAAAATGGATACTGAATTAGCAGAATCTGGATCCAATTTCAGTGTTGGACAGAGACAGTTAGTGTGCC TTGCAAGGGCCATTCTAAAGAATAACCGAATACTGATCATTGATGAAGCAACTGCAAATGTGGACCCAAG AACGGATGAGTTAATACAACAGAAGATCCGGGAGAAGTTTGCCCAGTGCACAGTGCTCACCATTGCTCAC AGACTGAACACCATCATTGACAGTGACAAGATAATGGTTTTGGATTCAGGAAGACTGAAAGAATATGATG AGCCGTATGTCTTGCTGCAGAATCCAGAGAGCCTCTTTTACAAGATGGTTCAGCAACTGGGCAAGGGCGA AGCCGCTGCCCTCACCGAAACAGCAAAACAGGTATACTTCAGACGGAATTACCCAGATATTACATTCACC AGCCCCGCGGTTATGAACACCTCCAATGGACAGCCCTCGGCCTTAACAATATTTGAAACAGCATTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001163675 |
| Insert Size | 3849 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001163675.1, NP_001157147.1 |
| RefSeq Size | 5711 bp |
| RefSeq ORF | 3849 bp |
| Locus ID | 239273 |
| UniProt ID | Q3TZN9 |
| Gene Summary | ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates also the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4). The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotics molecules (Probable). Confers resistance to anticancer agents (Probable).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG215161 | Abcc4 (tGFP-tagged) - Mouse ATP-binding cassette sub-family C (CFTR/MRP) member 4 (Abcc4) transcript variant 2, (10ug) |
CNY 14,540.00 |
|
| MR215161 | Abcc4 (Myc-DDK-tagged) - Mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), transcript variant 2 |
CNY 13,210.00 |
|
| MR215161L3 | Lenti ORF clone of Abcc4 (Myc-DDK-tagged) - Mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), transcript variant 2 |
CNY 15,110.00 |
|
| MR215161L4 | Lenti ORF clone of Abcc4 (mGFP-tagged) - Mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), transcript variant 2 |
CNY 15,110.00 |
