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Lmtk3 (NM_001005511) Mouse Untagged Clone
CAT＃: MC224432
Lmtk3 (untagged) - Mouse lemur tyrosine kinase 3 (Lmtk3), (10ug)
CNY 18,340.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | aatyk3; BC059845 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224432 representing NM_001005511
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCTGCACCCGGCGCACTCATCCTCCTGGCGGCCGTCTCCGCCTCCGGCTGCCTGGCGTCCCCAGCGC ACCCGGATGGATTCGCTCTGAGCCGGGCCCCTTTGGCTCCGCCCTACGCTGTGGTCCTCATTTCCTGTTC GGGTCTGCTGGCCTTCATCTTTCTCCTCCTTACCTGTCTGTGTTGCAAACGGGGTGATGTTCGTTTCAAG GAGTTTGAGAACCCGGAAGGGGAGGACTGCTCTGGGGAGTACACCCCCCCTGCGGAGGAGACCTCCTCCT CACAGTCGCTGCCTGATGTCTATATTCTGCCGCTGGCAGAGGTCTCACTGCCAATGCCTGCCCCGCAGCC TCCACACTCAGACATCAGCACCCCCCTGGGCCTGAGCCGCCAGCACCTCAGCTACCTGCAGGAGATTGGC AGCGGCTGGTTTGGGAAGGTGATCCTCGGGGAGGTTTTCTCAGACTACTCGCCAGCCCAGGTGGTGGTGA AGGAACTCCGGGCTAGTGCCGGGCCCCTGGAACAGCGCAAGTTCATCTCCGAGGCTCAGCCCTACAGGAG CCTGCAGCATCCCAACGTCCTCCAGTGCCTGGGCGTCTGTGTGGAGACCTTGCCCTTCCTGTTGATCATG GAGTTCTGCCAGCTGGGGGACCTGAAGCGATACCTTCGGGCCCAGCGGCCACCTGAAGGCATGTCCCCTG AACTTCCCCCTCGAGACCTTCGGACACTGCAGAGGATGGGTCTAGAGATTGCCCGAGGACTGGCACACCT GCACTCTCACAACTATGTGCACAGCGATCTGGCGCTGCGCAACTGCCTGCTAACTTCAGACCTGACTGTG CGTATTGGAGACTATGGGCTGGCGCACAGCAACTACAAGGAAGACTACTACCTGACACCCGAGCGCCTAT GGGTGCCGCTGCGCTGGGCAGCGCCCGAGCTGCTGGGCGAGCTGCACGGCAGCTTCGTGCTGGTAGATCA AAGCCGGGAGAGTAATGTCTGGTCCCTGGGGGTGACACTCTGGGAGCTATTCGAGTTCGGGGCACAGCCC TATCGTCACCTATCGGATGAGGAGGTCCTGGCCTTTGTTGTCCGCCAGCAGCACGTGAAGCTGGCCCGGC CCAGGCTCAAGCTGCCCTACGCTGACTATTGGTATGACATTTTGCAGTCTTGCTGGCGGCCGCCAGCCCA GCGCCCCTCAGCTTCTGATCTCCAGCTGCAGCTCACTTACCTGCTGTCTGAGCGGCCCCCCAGGCCCCCT CCTCCACCACCCCCTCCCCGAGATGGGCCCTTCCCCTGGCCCTGGCCCCCCTCGCATAGTGCGCCGCGCC CAGGGACCCTGTCCTCCCAGTTCCCCCTTCTGGATGGCTTCCCCGGGGCTGACCCTGATGATGTACTCAC AGTCACCGAGAGCAGCCGTGGCCTCAACCTTGAGTGCCTGTGGGAGAAGGCCCGCCGTGGGGCAGGCCGG GGTGGGGGTGCACCTCCCTGGCAACCCGCTTCTGCGCCTCCTGCGCCCCATACCAATCCATCCAATCCCT TCTATGAGGCGCTGTCCACCCCTAGCGTGCTTCCGGTCATCAGCGCACGCAGTCCCTCGGTGAGCAGCGA GTACTATATCCGCCTGGAGGAGCACGGTTCTCCACCAGAGCCCCTCTTCCCCAACGACTGGGACCCGCTG GACCCAGGAGTACCCGGTCCCCAGGCCCCCCAGACTCCCTCCGAGGTCCCTCAGCTGGTGTCCGAGACCT GGGCTTCCCCCCTCTTCCCCGCGCCCCGACCCTTCCCGGCCCAGTCCTCGGGATCAGGTGGTTTCCTGCT GAGCGGCTGGGACCCCGAGGGCCGGGGCGCAGGAGAGACCCTGGCAGGAGATCCTGCCGAGGTGCTTGGG GAACAGGGTACCGCACCCTGGGCCGAAGAGGAGGAGGAAGAGAGCTCCCCAGGCGAGGACAGCAGCAGCC TTGGAGGGGGACCCAGCCGCAGGGGACCCCTCCCCTGTCCCTTGTGCAGCCGCGAGGGTCCCTGCTCCTG TCTGCCATTGGAGCGGGGGGACGCTGTGGCCGGCTGGGGGGACCACCCTGCCCTTGGTTGTCCCCACCCC CCAGAGGACGACTCTTCCTTGCGTGCAGAGCGGGGCTCCTTGGCCGACCTGCCTCTGGTCCCCCCTACCT CAGCCCCTCTCGAGTTTCTGGACCCCCTTATGGGGGCCGCAGCGCCCCAGTACCCCGGGCGGGGGCCACC TCCCGCTCCCCCCCCTCCACCGCCCCCTCCCCGGGCCTCCGCGGAACCGGCCGCGTCCCCCGACCCCCCG TCGGCCCTGGCCAGTCCAGGCTCCGGCCTATCGTCTCCGGGCCCCAAGCCGGGGGACAGCGGCTACGAGA CCGAGACCCCTTTTTCCCCCGAGGGAGCCTTCCCAGGTGGGGGGGCGGCCGAGGAGGAAGGGGTCCCTCG GCCACGGGCTCCCCCCGAGCCACCCGACCCAGGAGCGCCCCGGCCACCCCCAGACCCGGGTCCCCTCCCA CTCCCAGGGTCCCAGGAGAAGCCAACCTTTGTAGTTCAGGTGAGCACCGAGCAGCTGCTGATGTCCCTAC GGGAGGATGTGACAAAGAACCTCCTAGGGGACAAGGGGTCGACACCCGGGGAGACAGGACCCAGGAAGGC GGGGAGAAGCCCCGCGAACAGAGAGAAGGGCCCAGGCCCGAACAGGGACCTGACATCCCTGGTCAGCAGG AAGAAAGTCCCCAGCAGGAGCCTTCCAGTGAACGGGGTGACAGTGTTGGAGAACGGGAAGCCAGGAGTCC CGGACATGAAGGAGAAGGTGGCGGAGAATGGCCTGGAATCTCCGGAGAAAGAAGAGAGAGCCCTGGTGAA TGGGGAGCCGATGTCCCCAGAGGCCGGGGAGAAGGTGCTGGCGAATGGGGTTCTGATGTCCCCAAAGAGC GAGGAGAAGGTGGCAGAGAATGGGGTCCTGAGGCTGCCCAGGAACACGGAGAGGCCACCAGAGATTGGAC CTCGGAGAGTCCCAGGGCCCTGGGAGAAGACGCCCGAGACTGGGGGTCTAGCTCCCGAGACCCTGCTGGA TCGAGCCCCTGCGCCCTGCGAGGCAGCCTTGCCCCAGAACGGCTTGGAGATGGCCCCTGGCCAGCTTGGC CCAGCCCCCAAGAGCGGGAACCCAGACCCCGGGACCGAGTGGAGAGTCCACGAGAGTGGGGGGGCACCGA GAGCCCCCGGGGCTGGGAAGCTGGACCTCGGGAGTGGGGGCCGAGCCCTGGGGGGCGTGGGGACGGCCCC CGCCGGCGGCCCCGCAAGCGCCGTGGACGCAAAGGCCGGATGGGTAGACAACTCGAGACCACTGCCACCT CCGCCACAGCCACTGGGGGCCCAACAGAGGAGGCCGGAGCCAGTGCCCCTGAAAGCCAGGCCGGAGGTGG CCCAAGAGGAAGAGCCAGGGGTCCCAGACAACAGGCTCGGCGGAGACATGGCCCCCAGCGTAGACGAGGA CCCCCTCAAGCCGGAGAGGAAGGGCCCCGAGATGCCACGCTTGTTCCTGGACTTGGGACCACCTCAGGGG AACAGCGAGCAGATCAAAGCCAAACTCTCCCGGCTCTCGCTGGCGCTCCCACCGCTCACGCTCACGCCGT TCCCGGGCCCGGGCCCGCGGCGGCCACCTTGGGAGGGCGCGGACGCAGGGGCAGCTGGCGGGGAGGCCGG CGGGGCGGGGGCGCCGGGGCCAGCGGAGGAGGACGGGGAGGACGAGGACGAGGACGAGGAGGACGAGGAG GCAGCGGGCTCTCGGGATCCCGGGAGGACGCGGGAAGCCCCAGTGCCCGTCGTGGTGAGCAGCGCCGACG GGGACACGGTCCGCCCGCTGCGGGGGCTGCTCAAGTCTCCACGCGCGGCCGACGAGCCAGAGGACAGCGA GCTGGAGAGGAAGCGCAAGATGGTCTCCTTCCACGGGGACGTGACCGTCTACCTCTTCGACCAGGAGACT CCAACCAACGAGTTGAGCGTCCAGGGCACCCCCGAGGGGGACACGGAGCCATCAACTCCCCCAGCGCCCC CGACGCCTCCCCACCCCACCACCCCAGGAGATGGGTTTCCCAACAGCGACAGCGGCTTTGGCGGCAGTTT CGAGTGGGCGGAGGATTTCCCCCTCCTCCCCCCGCCAGGCCCCCCCCTGTGCTTCTCCCGCTTCTCCGTC TCACCTGCACTGGAGACCCCGGGGCCTCCCGCCCGGGCTCCCGACGCCCGGCCCGCAGGCCCCGTGGAGA ACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001005511 |
| Insert Size | 4275 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001005511.3, NP_001005511.2 |
| RefSeq Size | 4867 bp |
| RefSeq ORF | 4275 bp |
| Locus ID | 381983 |
| UniProt ID | Q5XJV6 |
| Gene Summary | Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (By similarity). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (PubMed:24760852).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211980 | Lmtk3 (tGFP-tagged) - Mouse lemur tyrosine kinase 3 (Lmtk3) |
CNY 11,880.00 |
|
| MR211980 | Lmtk3 (Myc-DDK-tagged) - Mouse lemur tyrosine kinase 3 (Lmtk3) |
CNY 9,744.00 |
|
| MR211980L3 | Lenti ORF clone of Lmtk3 (Myc-DDK-tagged) - Mouse lemur tyrosine kinase 3 (Lmtk3) |
CNY 12,730.00 |
|
| MR211980L4 | Lenti ORF clone of Lmtk3 (mGFP-tagged) - Mouse lemur tyrosine kinase 3 (Lmtk3) |
CNY 12,730.00 |
