Cdk12 (NM_001109628) Mouse Untagged Clone
CAT#: MC224531
Cdk12 (untagged) - Mouse cyclin-dependent kinase 12 (Cdk12), transcript variant 2, (10ug)
CNY 18,910.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | 1810022J16Rik; AI646528; Crk7; Crkrs; D11Ertd752e; Pksc |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC224531 representing NM_001109628
Red=Cloning site Blue=ORF Orange=Stop codon CTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCCGGCGC GCCC ATGCCCAATTCCGAGAGACATGGGGGCAAGAAGGACGGGAGCGGAGGAGCTTCTGGAACTTCGCAGCCGT CATCGGGAGGTGGCAGCTCCAACAGCAGGGAGCGTCACCGCTTGGTGTCGAAGCACAAGCGGCATAAGTC CAAGCACTCCAAAGACGTGGGGCTGGTGACCCCCGAAGCGGCATCTTTGGGTACCATAATCAAACCACTG GTGGAGTACGATGACATCAGCTCTGATTCAGACACCTTCTCCGATGACACGGCCTTCAAATCAGACCGGA GGGAGAACGAGGAACGTCGGGGAACGGATCGGAGCGATCGCCTGCACCGACATCGTCACCACCAGCACCG GCGGTCCCGAGACTTGCTAAAAACTAAACAGACGGAAAAGGAAAAAAATCAGGAAGTCTCCAAATCTGGA TCTATGAAGGACCGGGTATCGGGCAGTTCCAAACGGTCCGTGGAGGGGAGTGATGATTATGGGAAGGCCC AGCTATCCAAAAGCGGCAGCAAGGAATCCAGGTCGTCCAAAATGCACAAGGAGAAGACCCGCAAAGAGCG AGAGTTAAAGTCTGGATACAAGGACCGGAGTAAAAGTCATCGGAAAAGGGAAACACCCAAAAGTTACAAA ACCGTGGCTAGCCCTAAACGGAGATCCAGGAGTCCCCATAGGAAATGGTCTGACAGTTCCAAGCAAGATG ACAGCCCTTCCGGAGCTTCTTATGGCCAAGACTACGATCTTAGCCCCCCAAGGTCTCACACTTCTAGCAA CTATGACTCCTACAAGAAGAGTCCTGGAAGTACCTCAAGAAGGCAGTCAATCAGCCCACCTTACAAAGAG CCTTCTGCTTACCAGTCCAGCACTCGGTCACCCAGTCCTTACAGCCGACGACAGAGGTCTGTGAGTCCCT ATAGCCGGAGACGGTCCTCCAGCTATGAAAGGAGCGGCTCTTACAGCGGGAGATCACCCAGCCCCTATGG CCGAAGGCGATCAAGCAGCCCTTTCCTGAGCAAGAGGTCTCTGAGTCGGAGTCCACTCCCCAGTAGGAAA TCCATGAAGTCCAGAAGTAGAAGTCCTGCATATTCAAGACACTCATCTTCTCATAGTAAAAAGAAGCGAT CCGGGTCACGCAGTCGTCATTCCAGTATCTCACCTGTCAGGCTTCCATTGAATTCCAGCCTGGGAGCTGA ACTCAGTAGAAAAAAGAAGGAAAGAGCAGCAGCTGCTGCAGCAGCAAAAATGGATGGAAAAGAGTCCAAG AGTTCACCTATAATTTTGCCTAAAAAAGAGAAACTTGAGGTGAAGGAGTCAGGGTTAGAGTCTAAAAAGT TACCCAGAAGTATAAAATCAGAAAAATCGACCCCAGATACTGAACTGGTTACTGTAGCACATTCAAACCC AGAGGTAAAACATTGTTTAGACACAGGGAAGGTTAGGTTGGATGAGAACTTGCAGAAGCATCCTGCTAAG GATTTGAAAGCACAGGGAACAAAGGACGTTAAACCTGTAGCACCGAAAGAGGTGATTGTTACTTCAAAGG AGACAGAGACATCAGAAAAGGAGACCCTTCCACCTCTTCCCACAATTACTTCTCCACCCCCTTTACCAGC TACTACCCCTCCACCTCAGACACCCCCTTTGCCACCTTTGCCTCCACTACCAGCTATTCCGCTGCAGCCA CCTCTGCCTCCTCCCCAACCACCATTTAGTCAAGTTCCTGTTTCAAGTACTTCAATTTTACCCTCTTCTC CTCACCCAAGGACATCTACTCTATCCTCTCAGACAAATTCTCAGCCCCCTGTACAGGTTTCTATGAAGAC TCAAGTATCTATAACAGCTGCTATTCCACATCTGAAGACTTCAACATTGCCTCCTCTGCCCCTCCCTCCC CTATTACCTGGAGATGATGACATGGATAGTCCAAAAGAAACACTTCCTTCAAAGCCTGCAAAGAAAGAGA AGGAACAGAGGACTCGCCACTTGCTTACAGACTTGCCTCTTCCTCCTGAGCTACCAGGAGGAGATCCATC GCCTCCAGATTCTCCAGAGCCAAAGGCAATTACACCACCTCAACAACCATATAAAAAGAGACCAAAAATT TGTTGTCCACGTTATGGAGAAAGAAGACAAACAGAAAGTGATTGGGGGAAGCGCTGTGTGGACAAGTTTG ACATTATTGGGATTATTGGAGAGGGGACCTATGGCCAAGTATATAAAGCCAAGGACAAAGACACAGGAGA ACTAGTAGCTCTGAAGAAGGTTCGGCTGGACAATGAGAAAGAGGGCTTCCCAATCACAGCCATCCGGGAG ATCAAGATTCTTCGTCAATTAGTTCACCAGAGTGTTGTAAACATGAAGGAAATTGTCACAGACAAACAAG ATGCACTGGATTTCAAGAAGGACAAAGGTGCCTTTTACCTTGTATTTGAATATATGGACCATGACTTAAT GGGACTGCTTGAATCAGGTTTGGTGCACTTTTCTGAGGACCATATCAAGTCATTTATGAAACAGCTAATG GAAGGACTGGATTACTGTCACAAAAAGAATTTCCTCCATCGGGATATTAAATGTTCTAACATTTTGCTGA ATAACAGCGGGCAAATCAAACTGGCAGATTTTGGACTTGCTCGGCTCTATAACTCTGAAGAGAGTCGCCC TTACACAAACAAAGTCATCACTCTTTGGTATCGACCTCCAGAGCTTCTTCTTGGAGAGGAAAGATACACA CCAGCCATTGATGTTTGGAGCTGTGGGTGCATCCTTGGAGAACTGTTCACAAAGAAACCTATTTTTCAAG CCAATTTAGAACTGGCTCAGCTAGAACTTATCAGTCGTCTCTGTGGTAGTCCTTGTCCAGCAGTGTGGCC TGATGTTATCAAGCTGCCCTACTTCAACACCATGAAACCGAAGAAGCAATACAGGAGACGCCTAAGAGAA GAATTCTCTTTCATTCCTTCAGCGGCACTTGATCTATTGGACCACATGCTGACACTGGATCCTAGCAAGA GGTGCACAGCTGAACAGACCCTACAGAGTGACTTTCTTAAAGATGTGGAACTCAGCAAAATGGCACCTCC AGACCTACCTCACTGGCAGGATTGCCATGAATTGTGGAGTAAGAAACGTCGACGGCAGCGACAGAGTGGT ATTGTGATAGAAGATCCACCTCCGTCCAAAGCTTCTAGAAAAGAAACTACCTCAGGGACAACAGCTGAGC CTGTGAAAAACAATAGCCCAGCACCACCTCAGCCTGCTCCTGTCAAGGCAGAGCCTGGTCCAGGGGATGC AGTAGGCCTTGGTGACATCACACAGCAGTTGAATCAAAGTGAATTGGCAGTGTTATTAAACCTGCTTCAG AGCCAAACTGACCTGAGCATCCCTCAGATGGCACAGCTGCTTAATATCCACTCCAATCCAGAGATGCAAC AGCAGCTTGAAGCCTTGAATCAGTCTATTAGTGCACTGACTGAAGCCAGTTCCCAGCAGCAGGACTCAGA ATCCATAGCCCCTGAAGAATCATTGAAGGAGGTACCTTCTGTACCTGTGGTCCTGCCTCCTGCTGAACAG ACAACTCCTGAAGCTTCAAACACACCAGCTGACATGCAGAATGTGTTGGCAGTTCTCTTGAGTCAGCTGA TGAAAACCCAAGAGCCAGCAGGTAACCTGGAGGAAAACACCAATGACAAGAATAGTGGGCCACAGGGGCC CCGAAGAACTCCTACAATGCCACAGGAGGAGGCAGCAGAGAAGAGGCCCCCTGAGCCCCCTGGACCTCCA CCGCCGCCACCTCCACCCCCTCTGGTTGAAGGCGATCTTTCCAGCGCCCCCCAGGAGTTGAATCCCGCCG TGACAGCCGCCTTGCTGCAACTTTTATCCCAGCCTGAAGCAGAGCCTCCTGGCCACCTGCCACATGAGCA CCAGGCCTTGAGACCAATGGAATACTCCACCCGATCCCATCCAAACAGGACTTACGGAAATACTGATGGG CCTGAGACAGGGTTCAGTTCCGCTGACACTGATGAACGCAGTTCTGGTCCAGCCTTGACAGAATCTTTGG TTCAGACCCCGGTGAAGAACAGGACCTTCTCAGGCTCTGTGAGCCACCTTGGGGAGTCCAACAGCTACCA GGGCACAGGGTCAGTGCAGTTCCCAGGGGACCAGGACCTCCGTTTTACCAGGGTTCCCTTAGCATTACAC TCAGTGGTTGGGCAACCATTCCTCAAGTCTGAGGGAAATAGCAACTCTGTGGTACATGCAGAGACCAAAT TGCAAAACTATGGGGAGCTGGGACCGGGAACCACTGGGGCCAACAGCTCAGGAACAACGCTTCAGTGGGG GGGCCCAGCTCAGTCTTATGGAAAACCCTACAGGGGGGCTGCAAGAGTCCTACCACGAGGGGGAAGAGGG AGAGGAGTTCCTTATTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | AscI-MluI |
ACCN | NM_001109628 |
Insert Size | 4428 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001109628.1, NP_001103098.1 |
RefSeq Size | 7642 bp |
RefSeq ORF | 4428 bp |
Locus ID | 69131 |
UniProt ID | Q14AX6 |
Gene Summary | Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG215624 | Cdk12 (tGFP-tagged) - Mouse cyclin-dependent kinase 12 (Cdk12) transcript variant 2, (10ug) |
CNY 16,250.00 |
|
MR215624 | Cdk12 (Myc-DDK-tagged) - Mouse cyclin-dependent kinase 12 (Cdk12), transcript variant 2 |
CNY 14,730.00 |
|
MR215624L3 | Lenti ORF clone of Cdk12 (Myc-DDK-tagged) - Mouse cyclin-dependent kinase 12 (Cdk12), transcript variant 2 |
CNY 16,630.00 |
|
MR215624L4 | Lenti ORF clone of Cdk12 (mGFP-tagged) - Mouse cyclin-dependent kinase 12 (Cdk12), transcript variant 2 |
CNY 16,630.00 |