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Nrxn1 (NM_177284) Mouse Untagged Clone
CAT＃: MC224600
Nrxn1 (untagged) - Mouse neurexin I (Nrxn1), transcript variant 2, (10ug)
CNY 19,190.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1700062G21Rik; 9330127H16Rik; A230068P09Rik; mKIAA0578 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224600 representing NM_177284
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGACGGCGCTGGTCCAGCGCGGGGGCTGCTGTCTCCTCTGCCTGTCGCTGCTGCTGCTGGGCTGCT GGGCAGAGCTGGGCAGCGGGCTGGAGTTCCCGGGCGCCGAGGGCCAGTGGACGCGCTTCCCCAAGTGGAA CGCGTGCTGCGAGAGCGAGATGAGCTTCCAGCTGAAGACGCGCAGTGCCCGCGGCCTCGTGCTCTACTTC GACGACGAGGGCTTCTGCGACTTCCTCGAGCTCATCCTGACGCGCGGCGGCCGCCTGCAGCTCAGCTTCT CCATCTTCTGCGCCGAGCCCGCCACGCTGTTGGCCGACACGCCGGTCAACGACGGCGCCTGGCACAGCGT GCGCATCCGCCGCCAGTTCCGCAACACCACGCTCTACATCGACCGCGCCGAGGCCAAGTGGGTGGAGGTC AAGTCCAAGCGCAGGGACATGACGGTGTTCAGCGGGCTCTTCGTGGGCGGCCTGCCACCCGAACTGCGCG CCGCGGCCCTCAAGCTCACGCTGGCCTCGGTGCGCGAGCGCGAGCCCTTCAAGGGCTGGATCCGTGACGT CCGGGTCAACTCGTCACAGGCCCTGCCGGTGGACGGCGGCGAGGTCAAGCTGGACGACGAGCCTCCCAAC AGCGGTGGCGGGAGCCCATGCGAGGCGGGCGAAGAAGGCGAGGGCGGCGTGTGCCTCAACGGGGGCGTGT GCTCCGTGGTCGACGACCAGGCCGTATGCGACTGCTCGAGGACCGGCTTCCGTGGCAAGGACTGCAGCCA AGAAGACAACAATGTGGAAGGTCTGGCACACCTGATGATGGGCGACCAAGGAAAAGAAGAGTATATTGCC ACGTTCAAGGGATCTGAATACTTCTGCTACGACTTATCTCAAAACCCCATTCAAAGCAGCAGTGATGAAA TAACTCTGTCCTTTAAAACTCTTCAAAGGAACGGACTGATGCTTCACACAGGGAAATCAGCTGATTATGT CAATCTTGCATTGAAAAATGGAGCTGTCTCTCTGGTCATTAATTTGGGATCAGGGGCCTTTGAAGCACTA GTGGAGCCTGTGAATGGAAAGTTTAATGATAATGCCTGGCATGATGTGAAAGTCACCAGGAATCTGCGTC AGGTGACAATATCAGTGGATGGAATTCTTACCACAACGGGCTACACGCAAGAAGATTACACCATGCTGGG GTCTGATGACTTTTTCTATGTTGGAGGCAGCCCCAGCACAGCCGACCTTCCAGGGTCACCAGTCAGTAAC AACTTTATGGGCTGTCTCAAAGAGGTTGTATATAAAAATAATGATGTAAGGCTGGAATTATCGCGACTTG CCAAGCAAGGAGATCCTAAGATGAAGATTCACGGTGTGGTGGCTTTTAAGTGTGAAAATGTGGCAACCTT AGACCCAATAACTTTTGAGACCCCGGAATCTTTCATTTCTTTGCCTAAGTGGAATGCAAAGAAAACAGGC TCAATATCATTTGATTTCCGTACAACGGAGCCAAATGGCCTCATCCTGTTTAGCCATGGCAAGCCAAGAC ATCAGAAGGATGCCAAGCACCCACAGATGATTAAGGTTGACTTTTTTGCTATTGAGATGCTGGATGGCCA CTTGTACCTCCTCTTAGACATGGGATCAGGTACTATAAAAATCAAAGCCCTGCAGAAGAAAGTCAATGAT GGAGAATGGTATCACGTGGATTTCCAACGGGATGGACGGTCAGGTACCATTTCTGTCAACACACTACGCA CTCCCTACACAGCTCCCGGTGAGAGTGAGATCCTGGACCTAGATGATGAGTTGTACCTGGGTGGCTTGCC AGAAAATAAGGCTGGCCTAGTCTTCCCTACCGAGGTGTGGACTGCTCTGCTCAACTACGGCTACGTGGGC TGCATCCGGGACCTATTTATTGATGGCCAGAGCAAAGACATCCGGCAGATGGCGGAAATTCAGAGCACTG CTGGAGTGAAGCCATCCTGCTCAAAAGAGACAGCAAAACCGTGCCTTAGCAATCCTTGCAAAAACAATGG CATGTGCAGAGATGGCTGGAACAGATACGTCTGCGATTGCTCCGGAACAGGCTATCTCGGCAGGTCCTGT GAGAGAGAGGCAACGGTTTTGAGCTACGACGGGAGCATGTTCATGAAAATCCAGCTTCCGGTGGTGATGC ACACTGAGGCTGAGGACGTGTCCTTGCGGTTCCGATCCCAGCGTGCATATGGTATCCTGATGGCGACCAC TTCTAGAGACTCTGCAGACACCCTTCGATTGGAGCTAGATGCAGGACGTGTGAAACTCACGGTCAATCTA GATTGTATCAGGATTAACTGTAATTCCAGCAAAGGTCCTGAGACCCTTTTTGCTGGCTATAACCTCAATG ATAATGAATGGCACACAGTGCGTGTGGTTCGGCGAGGAAAAAGTTTAAAGCTAACCGTGGATGATCAACA AGCCATGACAGGCCAAATGGCAGGTGATCATACAAGGCTGGAGTTTCATAACATAGAGACAGGCATCATC ACCGAACGACGCTACCTTTCTTCTGTCCCCTCCAATTTCATTGGGCACCTGCAAAGCCTGACATTTAATG GAATGGCATACATAGACTTGTGCAAAAATGGTGATATAGATTACTGTGAACTCAATGCCAGGTTTGGATT CAGGAACATCATCGCAGATCCTGTCACCTTCAAGACCAAATCGAGCTATGTTGCCTTAGCTACATTGCAA GCCTACACCTCTATGCATCTATTTTTCCAATTCAAGACAACATCTCTAGATGGACTAATTCTGTATAACA GTGGGGATGGAAATGACTTTATTGTGGTTGAATTAGTTAAAGGGTACTTACATTATGTGTTTGACTTGGG AAACGGTGCTAACCTCATCAAAGGGAGCTCAAACAAACCACTCAACGACAATCAGTGGCACAATGTGATG ATTTCACGGGACACCAGCAATCTCCACACAGTAAAGATCGACACAAAAATCACAACACAAATCACTGCGG GAGCCAGAAATCTAGACCTCAAGAGTGACTTGTATATTGGAGGAGTGGCTAAAGAAACATATAAATCCCT GCCAAAACTGGTCCATGCCAAAGAAGGCTTTCAAGGTTGCCTGGCATCTGTGGACTTGAATGGCAGACTT CCAGATCTCATCTCGGATGCTCTCTTCTGCAATGGGCAAATTGAGAGAGGATGCGAAGGGCCCAGCACAA CCTGCCAAGAGGATTCATGTTCAAATCAAGGCGTTTGCTTGCAGCAATGGGATGGCTTCAGCTGTGACTG TAGCATGACTTCCTTCAGTGGCCCACTCTGCAATGACCCTGGGACAACATATATCTTTAGCAAAGGTGGT GGACAGATTACATATAAGTGGCCTCCCAATGACCGCCCCAGTACACGAGCAGACAGGCTGGCCATCGGAT TTAGCACTGTCCAGAAGGAAGCCGTGTTGGTGCGTGTGGACAGTTCCTCAGGACTGGGTGACTACCTGGA GCTGCACATACACCAAGGAAAAATTGGAGTTAAGTTTAATGTTGGGACAGATGACATCGCCATCGAAGAG TCTAATGCAATCATTAATGATGGGAAATACCATGTAGTACGTTTCACAAGGAGTGGTGGCAATGCCACGT TACAGGTGGACAGCTGGCCAGTTATCGAACGCTACCCTGCAGGAAACAATGATAACGAGCGCCTGGCGAT TGCTAGACAGCGAATTCCATATCGACTTGGTCGAGTAGTTGATGAATGGCTACTCGACAAAGGGCGTCAG CTCACAATCTTCAATAGCCAAGCAACCATAATAATTGGCGGGAAAGAGCAGGGCCAGCCCTTCCAGGGCC AGCTCTCTGGTCTTTACTACAATGGCTTGAAAGTTCTGAATATGGCAGCAGAGAACGATGCCAACATCGC CATAGTGGGGAATGTGAGGCTGGTCGGTGAAGTGCCTTCCTCTATGACAACTGAGTCGACAGCCACTGCC ATGCAGTCTGAGATGTCCACCTCAATCATGGAGACCACCACAACCCTGGCTACCAGCACAGCTAGAAGAG GCAAGCCCCCCACAAAGGAACCCATCAGCCAGACCACAGATGACATCCTTGTGGCCTCGGCAGAGTGTCC CAGTGACGATGAGGACATTGACCCCTGTGAGCCGAGCTCAGGTGGGTTAGCCAACCCCACCAGAGTAGGT GGCCGTGAACCATACCCAGGCTCTGCAGAGGTGATTCGGGAGTCCAGCAGTACCACTGGCATGGTGGTGG GGATTGTCGCAGCAGCCGCTCTGTGCATCCTCATCCTCCTCTATGCCATGTACAAGTACAGGAACCGGGA TGAAGGGTCGTACCACGTGGATGAGAGTCGAAACTACATCAGTAACTCAGCACAGTCCAATGGGGCTGTG GTCAAGGAGAAGCAACCCAGCAGTGCTAAAAGCGCCAACAAAAACAAGAAAAACAAGGATAAGGAGTATT ACGTCTGA AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-RsrII |
| ACCN | NM_177284 |
| Insert Size | 4488 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_177284.2, NP_796258.2 |
| RefSeq Size | 9004 bp |
| RefSeq ORF | 4488 bp |
| Locus ID | 18189 |
| UniProt ID | Q9CS84 |
| Gene Summary | This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are synaptic transmembrane receptors that bind endogenous ligands that include neuroligins, dystroglycan, and neurexophilins. Neurexin complexes are required for efficient neurotransmission and are involved in synaptogenesis. In vertebrates, alternate promoter usage results in multiple isoform classes, of which the alpha and beta classes are the best characterized. In humans, allelic variants in this gene are associated with Pitt-Hopkins-like syndrome-2, while deletions have been associated with autism and schizophrenia. Mouse knockouts display decreased spontaneous and evoked vesicle release resulting in impaired synaptic transmission. In addition, knockout mice show altered social approach, reduced social investigation, reduced locomotor activity, and in males, increased aggression. Alternative splicing and promoter usage result in multiple transcript variants. [provided by RefSeq, Nov 2016] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226544 | Nrxn1 (tGFP-tagged) - Mouse neurexin I (Nrxn1) transcript variant 2, (10ug) |
CNY 16,440.00 |
|
| MR226544 | Nrxn1 (Myc-DDK-tagged) - Mouse neurexin I (Nrxn1), transcript variant 2 |
CNY 14,920.00 |
|
| MR226544L3 | Lenti ORF clone of Nrxn1 (Myc-DDK-tagged) - Mouse neurexin I (Nrxn1), transcript variant 2 |
CNY 16,820.00 |
|
| MR226544L4 | Lenti ORF clone of Nrxn1 (mGFP-tagged) - Mouse neurexin I (Nrxn1), transcript variant 2 |
CNY 16,820.00 |
