Notch2 (NM_010928) Mouse Untagged Clone

CAT#: MC225328

Notch2 (untagged) - Mouse Notch gene homolog 2 (Drosophila) (Notch2), (10ug)



  "NM_010928" in other vectors (2)

CNY 24,496.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (2)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms AI853703; N2
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC225328 representing NM_010928
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCCCGCTCTGCGTCCCGCCGCGCTGCGGGCGCTGCTGTGGCTCTGGCTGTGCGGCGCGGGCCCCGCGC
ACGCTTTGCAGTGTCGAGGTGGTCAAGAGCCCTGTGTAAATGAAGGGACCTGTGTTACCTACCACAACGG
CACAGGCTTCTGCCGATGTCCAGAGGGCTTCTTGGGAGAATATTGCCAACATCGAGACCCCTGTGAGAAA
AACCGCTGTCAGAATGGTGGTACTTGTGTGCCGCAGGGCATGTTGGGGAAAGCTACCTGCCGATGTGCTC
CAGGATTCACAGGAGAGGACTGCCAATACTCCACCTCTCACCCCTGCTTTGTGTCCCGCCCTTGTCAGAA
TGGGGGTACCTGTCACATGCTCAGCCGGGACACCTACGAGTGCACCTGCCAAGTCGGCTTCACAGGGAAG
CAGTGTCAGTGGACAGATGCCTGTCTATCTCATCCCTGCGAAAATGGAAGCACCTGTACATCTGTGGCCA
GCCAGTTCTCCTGCAAATGCCCTGCAGGCCTCACAGGGCAGAAGTGTGAAGCTGATATCAATGAGTGTGA
CATTCCAGGACGCTGCCAACATGGTGGCACCTGCCTCAACCTTCCTGGTTCCTACAGATGCCAATGTCCT
CAGGGCTTCACAGGCCAGCACTGTGACAGCCCTTATGTGCCCTGTGCACCCTCGCCCTGCGTCAACGGAG
GCACCTGTCGTCAGACTGGCGACTTCACTTTCGAATGCAACTGCCTGCCAGGTTTTGAAGGGAGCACCTG
TGAGCGGAATATCGACGACTGCCCCAACCACAAGTGTCAGAATGGAGGAGTTTGTGTGGATGGTGTCAAT
ACCTACAATTGCCGCTGTCCCCCTCAGTGGACTGGGCAGTTCTGCACAGAAGATGTGGACGAGTGTCTGT
TGCAGCCCAACGCTTGTCAGAATGGAGGCACCTGCACCAACCGAAACGGAGGCTATGGCTGCGTGTGTGT
GAACGGCTGGAGCGGAGATGACTGCAGCGAGAATATCGATGACTGTGCCTATGCTTCCTGCACGCCAGGG
TCCACCTGCATTGACCGCGTGGCCTCCTTCTCCTGCCTGTGTCCGGAGGGAAAGGCGGGTCTCCTGTGCC
ATCTGGATGATGCCTGTATCAGCAACCCTTGTCACAAGGGGGCGCTGTGTGACACCAACCCCCTGAACGG
GCAGTACATTTGCACCTGCCCACAGGGCTACAAGGGCGCTGACTGCACAGAAGACGTGGATGAGTGTGCT
ATGGCCAACAGTAACCCTTGTGAGCATGCAGGAAAGTGTGTGAATACAGATGGCGCCTTCCACTGTGAGT
GTCTGAAGGGCTACGCAGGGCCTCGCTGTGAGATGGACATCAACGAGTGTCATTCAGACCCCTGCCAGAA
CGACGCCACCTGCCTGGATAAGATCGGAGGCTTCACCTGTCTGTGCATGCCAGGTTTCAAAGGTGTGCAT
TGTGAGCTGGAGGTAAATGAATGCCAGAGCAACCCGTGTGTGAACAACGGGCAGTGTGTGGACAAAGTCA
ACCGCTTCCAGTGTCTGTGTCCCCCTGGCTTCACAGGACCAGTGTGCCAGATCGACATTGATGACTGCTC
CAGTACTCCCTGCCTGAATGGGGCCAAGTGCATCGATCACCCGAATGGCTATGAATGCCAGTGTGCCACA
GGTTTCACTGGCATATTGTGTGATGAGAACATCGACAACTGTGACCCAGATCCTTGCCACCATGGCCAGT
GCCAGGATGGGATCGACTCCTACACCTGCATCTGCAACCCTGGGTACATGGGAGCCATCTGTAGTGACCA
GATTGATGAATGCTACAGCAGCCCTTGCTTGAACGATGGGCGCTGCATTGACCTGGTGAATGGTTACCAG
TGCAACTGCCAACCAGGCACATCAGGCCTTAATTGTGAAATTAATTTTGATGACTGTGCCAGCAACCCTT
GTATGCACGGAGTCTGTGTGGACGGCATCAATCGCTACAGCTGTGTGTGCTCTCCGGGATTCACAGGCCA
GAGGTGCAATATTGACATTGATGAGTGTGCCTCCAACCCCTGTCGCAAGGGTGCGACGTGCATCAATGAT
GTGAATGGTTTCCGGTGTATATGCCCCGAGGGACCGCATCATCCTAGCTGCTACTCACAGGTGAACGAGT
GCCTGAGCAATCCCTGCATCCACGGAAACTGTACTGGAGGTCTCAGTGGCTATAAGTGCCTCTGCGATGC
AGGCTGGGTTGGTGTCAACTGTGAGGTGGACAAAAATGAGTGTCTTTCTAACCCATGCCAGAATGGAGGA
ACGTGCAATAACCTGGTGAATGGCTACAGGTGTACCTGCAAGAAGGGGTTCAAAGGCTACAACTGCCAGG
TGAATATAGATGAGTGTGCCTCCAACCCGTGTCTGAACCAAGGAACCTGCTTTGATGACGTCAGTGGCTA
CACTTGCCACTGCATGTTGCCTTACACAGGCAAGAACTGTCAAACAGTGTTGGCTCCCTGTTCCCCAAAC
CCGTGTGAGAATGCTGCTGTTTGTAAAGAGGCACCCAATTTTGAGAGCTTCAGCTGCTTGTGTGCTCCTG
GCTGGCAAGGTAAACGATGTACAGTTGACGTTGATGAGTGTATCTCCAAGCCGTGTATGAACAATGGTGT
CTGCCACAACACTCAGGGCAGCTACGTGTGTGAGTGTCCTCCCGGCTTCAGTGGGATGGACTGTGAAGAG
GACATCAATGATTGCCTTGCCAACCCCTGCCAGAACGGAGGCTCCTGTGTGGACCATGTGAATACCTTCT
CCTGCCAGTGCCATCCTGGCTTCATAGGGGACAAGTGCCAGACAGACATGAATGAGTGTCTGAGCGAGCC
CTGTAAGAATGGGGGGACCTGCTCCGACTATGTCAACAGTTACACCTGCACATGCCCTGCGGGCTTCCAC
GGAGTCCACTGTGAAAACAACATTGACGAGTGCACTGAGAGCTCCTGCTTCAATGGCGGCACGTGTGTTG
ATGGAATCAACTCTTTCTCTTGCTTGTGCCCCGTGGGTTTCACTGGTCCCTTCTGCCTCCATGATATCAA
TGAGTGCAGCTCTAACCCGTGCCTGAATGCTGGAACGTGTGTTGATGGTCTGGGTACCTACCGATGCATC
TGTCCCTTGGGCTACACCGGGAAAAACTGTCAGACCCTGGTGAACCTCTGCAGCCGGTCTCCGTGTAAAA
ACAAAGGAACTTGTGTTCAGGAAAAGGCAAGGCCCCACTGTCTGTGTCCGCCTGGATGGGATGGTGCATA
CTGTGATGTGCTCAACGTGTCCTGTAAGGCGGCAGCCTTGCAGAAAGGAGTACCTGTTGAACACTTGTGC
CAGCACTCGGGCATCTGTATCAATGCTGGCAACACCCATCACTGCCAGTGCCCCCTGGGCTACACGGGGA
GCTACTGCGAGGAGCAGCTTGATGAGTGTGCATCCAATCCATGCCAGCACGGTGCCACCTGCAATGACTT
CATCGGAGGATACAGATGTGAGTGTGTTCCAGGATATCAGGGTGTCAACTGTGAGTATGAAGTGGACGAG
TGCCAGAACCAACCCTGCCAGAATGGAGGCACCTGCATCGACCTTGTGAACCATTTCAAGTGTTCGTGTC
CCCCAGGCACCCGGGGCCTGCTGTGTGAAGAGAACATCGATGAATGTGCTGGGGGCCCCCACTGCCTTAA
CGGTGGCCAGTGCGTGGACCGGATTGGAGGCTACACTTGTCGCTGTTTGCCTGGCTTTGCTGGGGAGCGG
TGTGAGGGGGACATCAACGAATGCCTGTCCAACCCTTGCAGCTCAGAGGGCAGCCTGGACTGCGTTCAGC
TCAAAAATAACTACAACTGTATCTGCCGCAGCGCCTTCACGGGCCGGCACTGTGAAACCTTCCTAGATGT
GTGTCCCCAGAAGCCTTGCCTGAACGGAGGGACTTGTGCCGTGGCTAGCAACATGCCCGATGGCTTCATC
TGTCGTTGTCCCCCAGGGTTCTCTGGGGCGAGATGCCAGAGCAGCTGTGGACAAGTGAAGTGCAGGAGAG
GGGAGCAGTGTATCCACACTGACTCGGGACCTCGCTGCTTCTGCCTGAACCCCAAGGACTGCGAGTCAGG
ATGTGCCAGTAACCCCTGCCAGCATGGGGGCACCTGCTATCCTCAGCGCCAGCCTCCTCACTATTCCTGC
CGCTGCCCTCCGTCGTTCGGGGGCAGCCACTGCGAACTCTACACAGCCCCCACCAGCACCCCTCCTGCTA
CCTGTCAGAGTCAGTACTGCGCCGACAAGGCTCGGGATGGCATCTGTGACGAGGCCTGCAATAGTCATGC
CTGCCAGTGGGATGGAGGTGACTGTTCCCTCACTATGGAGGACCCCTGGGCCAACTGCACCTCCACTCTT
CGCTGCTGGGAATACATCAACAACCAGTGTGATGAGCAGTGCAACACCGCAGAGTGCCTGTTTGACAACT
TTGAGTGCCAGAGGAATAGCAAGACGTGCAAGTATGACAAATACTGTGCAGACCACTTCAAAGACAACCA
CTGTGATCAGGGATGCAACAGCGAGGAGTGTGGCTGGGATGGGCTGGACTGCGCTTCGGACCAGCCTGAG
AACCTGGCAGAGGGCACCCTGATCATCGTGGTGCTCCTGCCCCCTGAACAGCTGCTGCAGGATTCGCGAA
GCTTCTTGAGGGCCCTGGGCACCCTGCTCCACACCAACTTGCGCATTAAACAAGATTCTCAGGGCGCTCT
CATGGTGTACCCCTACTTTGGGGAGAAGTCAGCTGCCATGAAGAAGCAGAAGATGACACGCAGGTCTCTT
CCTGAGGAGCAGGAGCAGGAGCAGGAGGTGATAGGCTCTAAGATATTTCTGGAGATCGACAACCGACAGT
GTGTTCAAGATTCAGACCAGTGCTTCAAAAACACAGATGCGGCAGCTGCTCTCCTGGCTTCTCATGCCAT
CCAAGGGACCCTATCCTACCCTCTAGTGTCTGTTTTCAGTGAACTGGAGAGTCCAAGAAACGCCCAGCTT
CTCTATCTGCTCGCGGTCGCTGTTGTCATCATCCTGTTCTTCATCCTGCTGGGGGTCATCATGGCCAAGC
GGAAGCGCAAGCATGGCTTCCTCTGGCTGCCGGAAGGGTTCACCCTCCGCCGAGACTCTAGCAATCACAA
GCGCCGTGAACCTGTGGGACAGGATGCCGTGGGGCTGAAAAATCTCTCCGTGCAAGTGTCAGAGGCTAAC
CTGATTGGTTCTGGGACAAGTGAACATTGGGTTGATGATGAAGGACCCCAGCCAAAGAAAGCCAAGGCTG
AGGATGAGGCTTTGCTGTCGGAAGATGACCCCATCGATCGACGGCCCTGGACACAGCAGCACCTTGAAGC
TGCAGACATCCGCCACACTCCATCCCTGGCACTCACTCCTCCTCAGGCAGAACAGGAGGTGGACGTGCTG
GACGTGAATGTCCGAGGCCCAGATGGGTGTACTCCACTGATGCTGGCTTCTCTCCGAGGAGGCAGCTCAG
ACCTGAGTGATGAAGACGAAGATGCTGAGGACTCTTCTGCCAACATCATCACAGACTTGGTCTACCAAGG
TGCCAGCCTTCAAGCACAGACAGACCGCACTGGCGAGATGGCCCTGCACCTTGCAGCCCGCTATTCGAGA
GCTGATGCTGCCAAACGCCTCCTGGATGCTGGTGCGGATGCAAATGCCCAGGACAACATGGGCCGATGTC
CTCTTCACGCTGCGGTGGCAGCAGACGCCCAAGGTGTCTTTCAGATTCTGATCCGCAACCGTGTAACCGA
TCTGGATGCCAGAATGAACGATGGTACTACCCCCCTGATCCTGGCTGCCCGCCTGGCTGTGGAAGGAATG
GTGGCAGAGTTGATCAATTGCCAAGCAGATGTCAATGCAGTGGATGACCATGGAAAATCTGCCCTCCACT
GGGCAGCTGCTGTCAATAATGTGGAGGCGACTCTTCTGCTGTTGAAGAATGGGGCCAACAGAGATATGCA
GGACAATAAGGAAGAGACACCTTTGTTTCTTGCTGCCCGAGAGGGAAGTTATGAAGCGGCCAAAATCCTG
TTAGACCATTTTGCCAACCGGGACATCACTGACCACATGGACCGCCTTCCCCGGGATGTGGCTCGGGACC
GCATGCACCATGACATCGTTCGCCTCCTGGACGAGTATAACGTGACTCCCAGCCCTCCGGGAACGGTCTT
GACTTCTGCGCTCTCACCTGTCCTCTGTGGGCCCAACAGGTCTTTCCTCAGTCTGAAGCACACCCCAATG
GGTAAGAAGGCTAGGCGGCCCAACACCAAGAGCACCATGCCCACGAGCCTGCCTAACCTTGCCAAGGAGG
CCAAGGATGCCAAGGGCAGCAGGAGGAAGAAGTGTCTGAACGAGAAGGTCCAGCTGTCCGAGAGCTCAGT
GACTCTATCCCCCGTCGATTCGCTCGAGTCTCCTCACACGTATGTCTCCGATGCCACATCCTCTCCCATG
ATCACATCCCCTGGAATCTTACAGGCCTCGCCCACCCCCCTGCTGGCTGCTGCCGCCCCGGCTGCCCCAG
TGCACACACAGCATGCGCTGTCTTTCTCTAACCTTCATGACATGCAGCCTTTGGCTCCTGGAGCCAGCAC
CGTGCTCCCCTCGGTCAGCCAGCTGCTATCCCACCACCACATCGCGCCCCCAGGTAGTAGCAGTGCAGGA
AGCTTGGGCAGGTTACATCCAGTTCCTGTCCCAGCAGACTGGATGAACCGTGTGGAGATGAACGAGACCC
AGTACAGTGAAATGTTTGGCATGGTCCTGGCTCCTGCAGAGGGAGCCCACCCTGGCATAGCAGCTCCCCA
GAGCAGACCTCCGGAAGGGAAGCACATGTCCACCCAGCGGGAGCCCTTGCCTCCCATCGTGACTTTCCAG
CTTATCCCAAAAGGCAGCATTGCCCAGGCAGCCGGAGCTCCCCAGACGCAGTCCAGTTGCCCTCCAGCTG
TTGCAGGCCCCTTGCCCTCTATGTACCAGATCCCAGAGATGCCCCGTTTGCCCAGTGTGGCTTTCCCACC
TACCATGATGCCCCAGCAGGAGGGGCAGGTAGCTCAGACCATTGTGCCAACCTATCATCCTTTCCCAGCC
TCTGTGGGCAAGTACCCCACACCCCCTTCCCAACACAGTTACGCCTCCTCAAATGCTGCTGAGCGAACCC
CCAGTCATGGTGGTCACCTCCAGGGCGAGCACCCATACCTGACACCATCCCCAGAGTCTCCTGACCAATG
GTCAAGCTCTTCACCACACTCTGCATCTGACTGGTCAGATGTGACCACCAGCCCAACTCCTGGAGGTGGT
GGAGGCGGTCAGCGGGGACCCGGAACACACATGTCCGAGCCACCACACAGCAACATGCAGGTGTATGCAT
GA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_010928
Insert Size 7422 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_010928.2, NP_035058.2
RefSeq Size 10506 bp
RefSeq ORF 7422 bp
Locus ID 18129
UniProt ID O35516
Gene Summary Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination (PubMed:10393120). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus (PubMed:10393120, PubMed:18710934). Affects the implementation of differentiation, proliferation and apoptotic programs (PubMed:10393120, PubMed:18710934). May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation (By similarity). In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation (PubMed:18710934). Positively regulates self-renewal of liver cancer cells (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Other Versions

Customer Reviews 
Loading...