Glra1 (NM_001290821) Mouse Untagged Clone
CAT#: MC227795
Glra1 (untagged) - Mouse glycine receptor, alpha 1 subunit (Glra1), transcript variant 1
CNY 4,370.00
货期*
3周
规格
Product images
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经常一起买 (4)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | nmf11; oscillator; ot; spasmodic; spd |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC227795 representing NM_001290821
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTACAGCTTCAATACTCTGCGATTCTACCTTTGGGAGACCATTGTATTCTTCAGCCTTGCTGCTTCCA AAGAGGCTGAAGCCGCCCGCTCCGCACCCAAGCCTATGTCACCCTCGGACTTCCTGGATAAGCTCATGGG GAGGACTTCTGGGTATGACGCCAGGATCAGGCCCAACTTTAAAGGTCCTCCTGTGAATGTAAGTTGCAAC ATCTTCATCAACAGTTTCGGTTCCATCGCTGAGACAACCATGGACTATAGGGTCAACATCTTCCTGAGGC AGCAGTGGAACGACCCCCGTCTGGCCTACAATGAATACCCTGATGACTCTCTGGACCTTGACCCATCTAT GTTGGATTCCATCTGGAAGCCTGACTTGTTCTTTGCCAATGAGAAGGGGGCCCACTTCCACGAAATCACC ACGGACAACAAACTGCTAAGAATCTCCCGGAATGGCAATGTCCTCTACAGCATCAGAATCACCCTGACGC TGGCCTGCCCCATGGACCTGAAGAATTTCCCGATGGATGTACAGACGTGTATCATGCAACTCGAAAGCTT TGGATATACCATGAACGACCTCATCTTTGAGTGGCAGGAGCAAGGAGCTGTGCAGGTGGCAGACGGACTG ACCCTGCCTCAGTTTATTCTGAAGGAAGAGAAAGACCTGAGATACTGCACCAAGCACTACAACACAGGTA AATTCACCTGCATCGAGGCCCGATTCCACCTGGAGCGGCAGATGGGCTACTACCTGATCCAGATGTACAT CCCCAGCCTGCTCATCGTCATCCTGTCCTGGATCTCCTTCTGGATCAACATGGATGCTGCACCAGCTCGT GTGGGGCTGGGCATCACCACAGTGCTCACCATGACCACACAGAGCTCTGGCTCCCGAGCCTCCCTACCCA AGGTGTCCTACGTGAAAGCTATTGACATTTGGATGGCTGTTTGCCTGCTCTTCGTGTTCTCTGCCCTGCT GGAGTACGCCGCCGTCAACTTTGTGTCTCGGCAACACAAGGAACTGCTTCGATTTAGGAGGAAGAGGCGA CATCACAAGAGCCCCATGCTAAATCTGTTTCAGGATGATGAGGGTGGAGAAGGCCGCTTCAACTTCTCTG CCTATGGGATGGGCCCAGCCTGTCTGCAGGCCAAGGATGGCATCTCTGTCAAGGGTGCCAACAACAACAA CACCACTAACCCGCCTCCTGCGCCATCCAAGTCCCCGGAGGAGATGCGGAAACTCTTCATCCAGAGAGCC AAGAAGATCGACAAGATATCTCGCATCGGTTTCCCCATGGCCTTCCTCATCTTCAACATGTTCTACTGGA TCATCTATAAGATCGTCCGGAGAGAGGATGTCCACAACAAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001290821 |
Insert Size | 1374 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001290821.1, NP_001277750.1 |
RefSeq Size | 2413 bp |
RefSeq ORF | 1374 bp |
Locus ID | 14654 |
UniProt ID | Q64018 |
Gene Summary | Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:16672662, PubMed:17114051, PubMed:24801766). Channel opening is also triggered by taurine and beta-alanine (By similarity). Channel characteristics depend on the subunit composition; heteropentameric channels are activated by lower glycine levels and display faster desensitization (By similarity). Plays an important role in the down-regulation of neuronal excitability (PubMed:9145798). Contributes to the generation of inhibitory postsynaptic currents (PubMed:16672662, PubMed:17114051, PubMed:24801766). Channel activity is potentiated by ethanol. Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol (PubMed:24801766).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MR230006 | Glra1 (myc-DDK-tagged) - Mouse glycine receptor, alpha 1 subunit (Glra1), transcript variant 1 |
CNY 4,560.00 |
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