Kmo (NM_133809) Mouse Tagged ORF Clone
CAT#: MG207671
- TrueORF®
Kmo (tGFP-tagged) - Mouse kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (Kmo)
ORF Plasmid: DDK
"NM_133809" in other vectors (4)
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CNY 5,230.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | AI046660 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MG207671 representing NM_133809
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCATCGTCTGATACTCAGGGGAAAAGAGTGGCTGTTATTGGCGGTGGTTTGGTTGGAGCACTGAATG CCTGCTTTCTTGCAAAGAGGAATTTTCAAGTTGATGTGTACGAAGCTAGGGAAGATATTCGCGTGGCTAA ATCTGCACGTGGAAGGAGCATTAACTTGGCCCTTTCTTATAGAGGACGGCAGGCCTTGAAAGCCATTGGT CTGGAAGATCAGATCGTTTCCAAAGGTGTGCCCATGAAAGCCAGAATGATCCACTCTCTTTCGGGAAAGA AGTCTGCAATTCCCTATGGGAACAAGTCACAGTATATCCTTTCAATAAGCAGAGAAAACTTAAACAAGGA CCTGCTGACTGCCGTGGAGTCCTATGCCAATGCGAAGGTGCACTTTGGCCACAAGCTGTCGAAATGCATT CCGGAGGAAGGGGTACTCACAGTGCTCGGACCTGACAAGGTTCCCCGAGATGTCACATGTGACCTTGTTG TAGGGTGTGATGGAGCCTATTCAACTGTCAGAGCCCACCTCATGAAGAAGCCCCGCTTTGATTACACTCA GCAATATATCCCTCATGGATACATGGAGTTGACAATTCCACCTAAGAATGGGGAGTACGCCATGGAACCT AACTGTCTTCACATTTGGCCTAGAAATGCCTATATGATGATCGCCCTTCCAAACATGGACAAATCTTTCA CATGCACCTTGTTCATGCCCTTTGAGGAGTTTGAAAGACTTCCAACGCGCAGCGATGTGCTGGACTTCTT CCAGAAGAACTTTCCAGATGCTATCCCTCTGATGGGAGAGCAAGCCCTCATGAGAGATTTCTTTCTGTTG CCTGCCCAGCCCATGATATCAGTGAAGTGCTCTCCCTTCCACCTGAAGTCACACTGTGTGCTGATGGGAG ATGCCGCTCATGCCATTGTCCCATTTTTTGGGCAAGGAATGAATGCGGGCTTTGAAGACTGCTTGGTGTT TGATGAATTGATGGACAAATTCAATAATAATCTTAGTATGTGCCTTCCTGAATTCTCAAGATTTAGGATC CCAGATGACCATGCAATTTCAGACCTATCTATGTACAATTACATAGAGATGCGAGCGCATGTCAACTCTA GGTGGTTCCTGTTCCAAAAGCTCCTGGATAAATTTCTTCACGCGATCATGCCCTCTACCTTTATCCCTCT CTATACCATGGTCGCCTTCACCAGAATAAGATACCACGAGGCAGTGCTGCGTTGGCATTGGCAAAAAAAG GTGATAAACAGAGGACTCTTTGTCCTTGGGTCCCTGATAGCCATTGGAGGCACCTACCTACTTGTGCACC ATCTGTCCCTGAGACCTCTGGAGTTCTTGAGAAGACCTGCCTGGATGGGAACCACTGGCTACTGGACTAG GAGTACAGACATTTCTCTGCAAGTTCCATGGAGTTAC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG207671 representing NM_133809
Red=Cloning site Green=Tags(s) MASSDTQGKRVAVIGGGLVGALNACFLAKRNFQVDVYEAREDIRVAKSARGRSINLALSYRGRQALKAIG LEDQIVSKGVPMKARMIHSLSGKKSAIPYGNKSQYILSISRENLNKDLLTAVESYANAKVHFGHKLSKCI PEEGVLTVLGPDKVPRDVTCDLVVGCDGAYSTVRAHLMKKPRFDYTQQYIPHGYMELTIPPKNGEYAMEP NCLHIWPRNAYMMIALPNMDKSFTCTLFMPFEEFERLPTRSDVLDFFQKNFPDAIPLMGEQALMRDFFLL PAQPMISVKCSPFHLKSHCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNNLSMCLPEFSRFRI PDDHAISDLSMYNYIEMRAHVNSRWFLFQKLLDKFLHAIMPSTFIPLYTMVAFTRIRYHEAVLRWHWQKK VINRGLFVLGSLIAIGGTYLLVHHLSLRPLEFLRRPAWMGTTGYWTRSTDISLQVPWSY TRTRPLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_133809 |
ORF Size | 1437 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_133809.1, NP_598570.1 |
RefSeq Size | 2512 bp |
RefSeq ORF | 1440 bp |
Locus ID | 98256 |
UniProt ID | Q91WN4 |
Gene Summary | Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC216699 | Kmo (untagged) - Mouse kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (Kmo), (10ug) |
CNY 5,856.00 |
|
MR207671 | Kmo (Myc-DDK-tagged) - Mouse kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (Kmo) |
CNY 5,488.00 |
|
MR207671L3 | Lenti ORF clone of Kmo (Myc-DDK-tagged) - Mouse kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (Kmo) |
CNY 6,650.00 |
|
MR207671L4 | Lenti ORF clone of Kmo (mGFP-tagged) - Mouse kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (Kmo) |
CNY 6,650.00 |